Compile Data Set for Download or QSAR

Found 42 hits of Enzyme Inhibition Constant Data   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50017008(CHEMBL3287025)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280546BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50016982(CHEMBL3287027)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280546BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50384522(CHEMBL2036234)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280546BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50017007(CHEMBL3287026)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280546BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50384522(CHEMBL2036234)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280546BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50319665((S)-2-((1S,2S,4R)-Bicyclo[2.2.1]heptan-2-ylamino)-...)copy SMILEScopy InChI
Affinity DataIC50: 3.66nMAssay Description:Inhibition of adipose tissue-derived 11beta-HSD1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280546BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50016982(CHEMBL3287027)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280546BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50017010(CHEMBL3287024)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280546BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50016983(CHEMBL3220543)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of N-terminal His-tagged full length human 11beta-HSD1 assessed as inhibition of cortisone to cortisol conversion preincubated for 25 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280546BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50239401(3-Adamantan-1-yl-6,7,8,9-tetrahydro-5H-[1,2,4]tria...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280546BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50017007(CHEMBL3287026)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280546BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50017008(CHEMBL3287025)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280546BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50017005(CHEMBL3287032)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280546BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50309934(2-(3-Benzoyl-4-hydroxy-1,1-dioxo-1H-1lambda*6*-ben...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280546BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50017012(CHEMBL3287034)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280546BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50239276(3-Adamantan-1-yl-4-methyl-5-phenyl-4H-[1,2,4]triaz...)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280546BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50117901(2-(2-(3-chloro-2-methylphenylsulfonamido)thiazol-4...)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280546BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50017014(CHEMBL3287033)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280546BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50017011(CHEMBL3220591)copy SMILEScopy InChI
Affinity DataIC50: 74nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280546BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50016983(CHEMBL3220543)copy SMILEScopy InChI
Affinity DataIC50: 82nMAssay Description:Inhibition of N-terminal His-tagged full length rat 11beta-HSD1 assessed as inhibition of cortisone to cortisol conversion preincubated for 25 mins m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280546BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50117900(3-Chloro-2-methyl-N-{4-[2-(4-methyl-piperazin-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 96nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280546BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50017013(CHEMBL3287028)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280546BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50239276(3-Adamantan-1-yl-4-methyl-5-phenyl-4H-[1,2,4]triaz...)copy SMILEScopy InChI
Affinity DataIC50: 109nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280546BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50017006(CHEMBL3219705)copy SMILEScopy InChI
Affinity DataIC50: 138nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280546BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50394442(CHEMBL2159075)copy SMILEScopy InChI
Affinity DataIC50: 229nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280546BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50117901(2-(2-(3-chloro-2-methylphenylsulfonamido)thiazol-4...)copy SMILEScopy InChI
Affinity DataIC50: 284nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280546BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50016984(CHEMBL3287029)copy SMILEScopy InChI
Affinity DataIC50: 287nMAssay Description:Inhibition of rat 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280546BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50017010(CHEMBL3287024)copy SMILEScopy InChI
Affinity DataIC50: 307nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280546BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50016983(CHEMBL3220543)copy SMILEScopy InChI
Affinity DataIC50: 310nMAssay Description:Inhibition of N-terminal His-tagged full length mouse 11beta-HSD1 assessed as inhibition of cortisone to cortisol conversion preincubated for 25 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280546BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50017011(CHEMBL3220591)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280546BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50016984(CHEMBL3287029)copy SMILEScopy InChI
Affinity DataIC50: 479nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280546BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50016984(CHEMBL3287029)copy SMILEScopy InChI
Affinity DataIC50: 528nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280546BPubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50239401(3-Adamantan-1-yl-6,7,8,9-tetrahydro-5H-[1,2,4]tria...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human 11beta-HSD2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280546BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50017004(CHEMBL3287031)copy SMILEScopy InChI
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280546BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50017003(CHEMBL3287030)copy SMILEScopy InChI
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280546BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50117900(3-Chloro-2-methyl-N-{4-[2-(4-methyl-piperazin-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 3.34E+3nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280546BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50309934(2-(3-Benzoyl-4-hydroxy-1,1-dioxo-1H-1lambda*6*-ben...)copy SMILEScopy InChI
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280546BPubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50117900(3-Chloro-2-methyl-N-{4-[2-(4-methyl-piperazin-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human 11beta-HSD2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280546BPubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Mus musculus (mouse))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50239401(3-Adamantan-1-yl-6,7,8,9-tetrahydro-5H-[1,2,4]tria...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mouse 11beta-HSD2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280546BPubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50117901(2-(2-(3-chloro-2-methylphenylsulfonamido)thiazol-4...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human 11beta-HSD2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280546BPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50384522(CHEMBL2036234)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280546BPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50309934(2-(3-Benzoyl-4-hydroxy-1,1-dioxo-1H-1lambda*6*-ben...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280546BPubMed
* indicates data uncertainty>20%