Compile Data Set for Download or QSAR

Found 11 hits of Enzyme Inhibition Constant Data   

TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Imperial College London

Curated by ChEMBL
LigandPNGBDBM50008859(CHEMBL3222141)copy SMILEScopy InChI
Affinity DataIC50: 1.55E+4nMAssay Description:Inhibition of recombinant human full length SIRT2 using fluorescent ZMAL as substrate after 4 hrs by homogeneous fluorescent deacetylase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN4815PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Imperial College London

Curated by ChEMBL
LigandPNGBDBM50496762(CHEMBL3222144)copy SMILEScopy InChI
Affinity DataIC50: 1.76E+4nMAssay Description:Inhibition of recombinant human full length SIRT2 using fluorescent ZMAL as substrate after 4 hrs by homogeneous fluorescent deacetylase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN4815PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Imperial College London

Curated by ChEMBL
LigandPNGBDBM50178769((+/-)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-c...)copy SMILEScopy InChI
Affinity DataIC50: 1.96E+4nMAssay Description:Inhibition of recombinant human full length SIRT2 using fluorescent ZMAL as substrate after 4 hrs by homogeneous fluorescent deacetylase assayMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Imperial College London

Curated by ChEMBL
LigandPNGBDBM50496763(CHEMBL3222149)copy SMILEScopy InChI
Affinity DataIC50: 2.98E+4nMAssay Description:Inhibition of recombinant human full length SIRT2 using fluorescent ZMAL as substrate after 4 hrs by homogeneous fluorescent deacetylase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN4815PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Imperial College London

Curated by ChEMBL
LigandPNGBDBM50156760((E)-2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N...)copy SMILEScopy InChI
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of recombinant human N-tagged GST-SIRT1 fusion protein using fluorescent ZMAL as substrate after 4 hrs by homogeneous fluorescent deacetyl...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN4815PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Imperial College London

Curated by ChEMBL
LigandPNGBDBM50309827(CHEMBL597845 | Salermide)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of recombinant human full length SIRT2 using fluorescent ZMAL as substrate after 4 hrs by homogeneous fluorescent deacetylase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN4815PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Imperial College London

Curated by ChEMBL
LigandPNGBDBM50309827(CHEMBL597845 | Salermide)copy SMILEScopy InChI
Affinity DataIC50: 7.60E+4nMAssay Description:Inhibition of recombinant human N-tagged GST-SIRT1 fusion protein using fluorescent ZMAL as substrate after 4 hrs by homogeneous fluorescent deacetyl...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN4815PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Imperial College London

Curated by ChEMBL
LigandPNGBDBM50496765(CHEMBL3222156)copy SMILEScopy InChI
Affinity DataIC50: 7.75E+4nMAssay Description:Inhibition of recombinant human full length SIRT2 using fluorescent ZMAL as substrate after 4 hrs by homogeneous fluorescent deacetylase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN4815PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Imperial College London

Curated by ChEMBL
LigandPNGBDBM50178769((+/-)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-c...)copy SMILEScopy InChI
Affinity DataIC50: 9.80E+4nMAssay Description:Inhibition of recombinant human N-tagged GST-SIRT1 fusion protein using fluorescent ZMAL as substrate after 4 hrs by homogeneous fluorescent deacetyl...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN4815PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Imperial College London

Curated by ChEMBL
LigandPNGBDBM50496764(CHEMBL3222152)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human full length SIRT2 using fluorescent ZMAL as substrate after 4 hrs by homogeneous fluorescent deacetylase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN4815PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Imperial College London

Curated by ChEMBL
LigandPNGBDBM50156760((E)-2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N...)copy SMILEScopy InChI
Affinity DataIC50: 1.03E+5nMAssay Description:Inhibition of recombinant human full length SIRT2 using fluorescent ZMAL as substrate after 4 hrs by homogeneous fluorescent deacetylase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN4815PubMed
* indicates data uncertainty>20%