Compile Data Set for Download or QSAR

Found 12 hits of Enzyme Inhibition Constant Data   

TargetSphingosine kinase 1(Homo sapiens (Human))
500 University Drive

Curated by ChEMBL
LigandPNGBDBM50017018(CHEMBL3183090)copy SMILEScopy InChI
Affinity DataKi:  4.30nMAssay Description:Competitive inhibition of C-terminal His6-tagged human recombinant SphK1 expressed in baculovirus-infected Sf9 cells using sphingosine as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CF5PubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
500 University Drive

Curated by ChEMBL
LigandPNGBDBM50443385(SPC-100270 | Safingol | Safingol HCl)copy SMILEScopy InChI
Affinity DataKi:  3.00E+3nMAssay Description:Competitive inhibition of SphK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CF5PubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
500 University Drive

Curated by ChEMBL
LigandPNGBDBM50017017(CHEMBL3287037)copy SMILEScopy InChI
Affinity DataKi:  3.10E+3nMAssay Description:Competitive inhibition of human recombinant SphK1 using sphingosine and ATP as substrate by ADP-Quest kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CF5PubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
500 University Drive

Curated by ChEMBL
LigandPNGBDBM50017017(CHEMBL3287037)copy SMILEScopy InChI
Affinity DataKi:  4.20E+3nMAssay Description:Competitive inhibition of human recombinant SphK2 using sphingosine and ATP as substrate by ADP-Quest kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CF5PubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
500 University Drive

Curated by ChEMBL
LigandPNGBDBM50017016(CHEMBL3287036)copy SMILEScopy InChI
Affinity DataKi:  4.30E+3nMAssay Description:Inhibition of SphK2 (unknown origin) using sphingosine and [gamma-32P]ATP as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CF5PubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
500 University Drive

Curated by ChEMBL
LigandPNGBDBM50240721((E)-(2S,3R)-2-Dimethylamino-octadec-4-ene-1,3-diol...)copy SMILEScopy InChI
Affinity DataKi:  5.00E+3nMAssay Description:Inhibition of SphK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CF5PubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
500 University Drive

Curated by ChEMBL
LigandPNGBDBM50393642(CHEMBL2158685)copy SMILEScopy InChI
Affinity DataKi:  9.80E+3nMAssay Description:Competitive inhibition of human recombinant SphK2 assessed as NBD-S1P formation using NBD-Sph as substrate by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CF5PubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
500 University Drive

Curated by ChEMBL
LigandPNGBDBM50240721((E)-(2S,3R)-2-Dimethylamino-octadec-4-ene-1,3-diol...)copy SMILEScopy InChI
Affinity DataKi:  1.20E+4nMAssay Description:Inhibition of SphK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CF5PubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
500 University Drive

Curated by ChEMBL
LigandPNGBDBM50393641(CHEMBL2158686)copy SMILEScopy InChI
Affinity DataKi:  2.70E+4nMAssay Description:Inhibition of SphK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CF5PubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
500 University Drive

Curated by ChEMBL
LigandPNGBDBM50017015(CHEMBL3287035)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of SphK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CF5PubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
500 University Drive

Curated by ChEMBL
LigandPNGBDBM50017015(CHEMBL3287035)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of SphK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CF5PubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
500 University Drive

Curated by ChEMBL
LigandPNGBDBM50443389(CHEMBL2376441)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Competitive inhibition of V5-His-tagged human SphK2 expressed in HEK293 cells assessed as S1P production using sphingosine and [gamma-32P]ATP as subs...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CF5PubMed
* indicates data uncertainty>20%