Compile Data Set for Download or QSAR

Found 7 hits of Enzyme Inhibition Constant Data   

TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Washington University in Saint Louis

Curated by ChEMBL
LigandPNGBDBM50446668(CHEMBL3113568)copy SMILEScopy InChI
Affinity DataIC50: 6.30nMAssay Description:Inhibition of PARP-1 (unknown origin) assessed as NAD+ consumption after 20 mins by fluorometric analysis in presence of activated DNAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3GVHPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Washington University in Saint Louis

Curated by ChEMBL
LigandPNGBDBM50446671(CHEMBL3113565)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of PARP-1 (unknown origin) assessed as NAD+ consumption after 20 mins by fluorometric analysis in presence of activated DNAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3GVHPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Washington University in Saint Louis

Curated by ChEMBL
LigandPNGBDBM50446667(CHEMBL3113569)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of PARP-1 (unknown origin) assessed as NAD+ consumption after 20 mins by fluorometric analysis in presence of activated DNAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3GVHPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Washington University in Saint Louis

Curated by ChEMBL
LigandPNGBDBM50446666(CHEMBL3113570)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of PARP-1 (unknown origin) assessed as NAD+ consumption after 20 mins by fluorometric analysis in presence of activated DNAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3GVHPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Washington University in Saint Louis

Curated by ChEMBL
LigandPNGBDBM50446670(CHEMBL3113566)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of PARP-1 (unknown origin) assessed as NAD+ consumption after 20 mins by fluorometric analysis in presence of activated DNAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3GVHPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Washington University in Saint Louis

Curated by ChEMBL
LigandPNGBDBM50446669(CHEMBL3113567)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of PARP-1 (unknown origin) assessed as NAD+ consumption after 20 mins by fluorometric analysis in presence of activated DNAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3GVHPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Washington University in Saint Louis

Curated by ChEMBL
LigandPNGBDBM27497(2-(dimethylamino)-N-(6-oxo-5,6-dihydrophenanthridi...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibition of PARP-1 (unknown origin) assessed as NAD+ consumption after 20 mins by fluorometric analysis in presence of activated DNAMore data for this Ligand-Target Pair
* indicates data uncertainty>20%