Compile Data Set for Download or QSAR

Found 65 hits of Enzyme Inhibition Constant Data   

TargetPhospholipase D1(Homo sapiens (Human))
University of Massachusetts Boston

LigandPNGBDBM123745(1-(4-methoxyphenyl)-3-(naphthalen-1-yl)-1H-pyrazol...)copy SMILEScopy InChI
Affinity DataIC50: 5nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM123745(1-(4-methoxyphenyl)-3-(naphthalen-1-yl)-1H-pyrazol...)copy SMILEScopy InChI
Affinity DataIC50: 10nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D2(Homo sapiens (Human))
University of Massachusetts Boston

LigandPNGBDBM123746(1-(4-methoxyphenyl)-3-phenyl-1H-pyrazolo[3,4-d]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 15nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D2(Homo sapiens (Human))
University of Massachusetts Boston

LigandPNGBDBM123744(5-Fluoro-N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo[d]imi...)copy SMILEScopy InChI
Affinity DataIC50: 15nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D1(Homo sapiens (Human))
University of Massachusetts Boston

LigandPNGBDBM123754(1-methyl-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 20nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D1(Homo sapiens (Human))
University of Massachusetts Boston

LigandPNGBDBM123744(5-Fluoro-N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo[d]imi...)copy SMILEScopy InChI
Affinity DataIC50: 25nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D1(Homo sapiens (Human))
University of Massachusetts Boston

LigandPNGBDBM50257541((1R,2R)-N-([S]-1-{4-[5-bromo-2-oxo-2,3-dihydro-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 36nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM50257541((1R,2R)-N-([S]-1-{4-[5-bromo-2-oxo-2,3-dihydro-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 50nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM123744(5-Fluoro-N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo[d]imi...)copy SMILEScopy InChI
Affinity DataIC50: 100nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D2(Homo sapiens (Human))
University of Massachusetts Boston

LigandPNGBDBM123753(3-methyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-am...)copy SMILEScopy InChI
Affinity DataIC50: 120nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM87245(CHEMBL492797 | ML272 | N-(2-(4-(2-Oxo-2,3-dihydro-...)copy SMILEScopy InChI
Affinity DataIC50: 125nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D2(Homo sapiens (Human))
University of Massachusetts Boston

LigandPNGBDBM123745(1-(4-methoxyphenyl)-3-(naphthalen-1-yl)-1H-pyrazol...)copy SMILEScopy InChI
Affinity DataIC50: 125nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D2(Homo sapiens (Human))
University of Massachusetts Boston

LigandPNGBDBM50345704(1-(tert-butyl)-3-(naphthalen-2-yl)-1H-pyrazolo[3,4...)copy SMILEScopy InChI
Affinity DataIC50: 150nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D1(Homo sapiens (Human))
University of Massachusetts Boston

LigandPNGBDBM123757(1,3-dimethyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine (...)copy SMILEScopy InChI
Affinity DataIC50: 150nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D2(Homo sapiens (Human))
University of Massachusetts Boston

LigandPNGBDBM123755(1-methyl-3-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-am...)copy SMILEScopy InChI
Affinity DataIC50: 150nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D2(Homo sapiens (Human))
University of Massachusetts Boston

LigandPNGBDBM87245(CHEMBL492797 | ML272 | N-(2-(4-(2-Oxo-2,3-dihydro-...)copy SMILEScopy InChI
Affinity DataIC50: 225nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D1(Homo sapiens (Human))
University of Massachusetts Boston

LigandPNGBDBM123746(1-(4-methoxyphenyl)-3-phenyl-1H-pyrazolo[3,4-d]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 250nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D1(Homo sapiens (Human))
University of Massachusetts Boston

LigandPNGBDBM123756(1-methyl-3-(naphthalen-2-yl)-1H-pyrazolo[3,4-d]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 250nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D1(Homo sapiens (Human))
University of Massachusetts Boston

LigandPNGBDBM87245(CHEMBL492797 | ML272 | N-(2-(4-(2-Oxo-2,3-dihydro-...)copy SMILEScopy InChI
Affinity DataIC50: 255nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM123746(1-(4-methoxyphenyl)-3-phenyl-1H-pyrazolo[3,4-d]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 275nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D2(Homo sapiens (Human))
University of Massachusetts Boston

LigandPNGBDBM123747(1-(tert-butyl)-3-phenyl-1H-pyrazolo[3,4-d]pyrimidi...)copy SMILEScopy InChI
Affinity DataIC50: 290nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D1(Homo sapiens (Human))
University of Massachusetts Boston

LigandPNGBDBM123748(1-(tert-butyl)-3-methyl-1H-pyrazolo[3,4-d]pyrimidi...)copy SMILEScopy InChI
Affinity DataIC50: 350nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D2(Homo sapiens (Human))
University of Massachusetts Boston

LigandPNGBDBM50229961(1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazo...)copy SMILEScopy InChI
Affinity DataIC50: 350nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM123751(1-(2-ethylphenyl)-3-(naphthalen-2-yl)-1H-pyrazolo[...)copy SMILEScopy InChI
Affinity DataIC50: 355nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM50345704(1-(tert-butyl)-3-(naphthalen-2-yl)-1H-pyrazolo[3,4...)copy SMILEScopy InChI
Affinity DataIC50: 375nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM50229961(1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazo...)copy SMILEScopy InChI
Affinity DataIC50: 385nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM123749(1-(2-ethylphenyl)-3-(naphthalen-1-yl)-1H-pyrazolo[...)copy SMILEScopy InChI
Affinity DataIC50: 390nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D1(Homo sapiens (Human))
University of Massachusetts Boston

LigandPNGBDBM50229961(1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazo...)copy SMILEScopy InChI
Affinity DataIC50: 426nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D2(Homo sapiens (Human))
University of Massachusetts Boston

LigandPNGBDBM87231(N-[2-(4-keto-1-phenyl-1,3,8-triazaspiro[4.5]decan-...)copy SMILEScopy InChI
Affinity DataIC50: 450nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM123750(1-(2-ethylphenyl)-3-phenyl-1H-pyrazolo[3,4-d]pyrim...)copy SMILEScopy InChI
Affinity DataIC50: 450nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D1(Homo sapiens (Human))
University of Massachusetts Boston

LigandPNGBDBM123760(3-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine (19))copy SMILEScopy InChI
Affinity DataIC50: 500nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D1(Homo sapiens (Human))
University of Massachusetts Boston

LigandPNGBDBM50345704(1-(tert-butyl)-3-(naphthalen-2-yl)-1H-pyrazolo[3,4...)copy SMILEScopy InChI
Affinity DataIC50: 500nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM123752(3‐(naphthalen‐1‐yl)‐1̴...)copy SMILEScopy InChI
Affinity DataIC50: 545nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D1(Homo sapiens (Human))
University of Massachusetts Boston

LigandPNGBDBM123747(1-(tert-butyl)-3-phenyl-1H-pyrazolo[3,4-d]pyrimidi...)copy SMILEScopy InChI
Affinity DataIC50: 550nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D1(Homo sapiens (Human))
University of Massachusetts Boston

LigandPNGBDBM123755(1-methyl-3-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-am...)copy SMILEScopy InChI
Affinity DataIC50: 620nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM123747(1-(tert-butyl)-3-phenyl-1H-pyrazolo[3,4-d]pyrimidi...)copy SMILEScopy InChI
Affinity DataIC50: 650nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM123756(1-methyl-3-(naphthalen-2-yl)-1H-pyrazolo[3,4-d]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 650nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D2(Homo sapiens (Human))
University of Massachusetts Boston

LigandPNGBDBM123752(3‐(naphthalen‐1‐yl)‐1̴...)copy SMILEScopy InChI
Affinity DataIC50: 675nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM123755(1-methyl-3-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-am...)copy SMILEScopy InChI
Affinity DataIC50: 695nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM3003(1,3-diphenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine |...)copy SMILEScopy InChI
Affinity DataIC50: 700nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM123748(1-(tert-butyl)-3-methyl-1H-pyrazolo[3,4-d]pyrimidi...)copy SMILEScopy InChI
Affinity DataIC50: 790nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM123754(1-methyl-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 800nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D1(Homo sapiens (Human))
University of Massachusetts Boston

LigandPNGBDBM123752(3‐(naphthalen‐1‐yl)‐1̴...)copy SMILEScopy InChI
Affinity DataIC50: 875nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D1(Homo sapiens (Human))
University of Massachusetts Boston

LigandPNGBDBM123753(3-methyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-am...)copy SMILEScopy InChI
Affinity DataIC50: 900nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D1(Homo sapiens (Human))
University of Massachusetts Boston

LigandPNGBDBM87231(N-[2-(4-keto-1-phenyl-1,3,8-triazaspiro[4.5]decan-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D2(Homo sapiens (Human))
University of Massachusetts Boston

LigandPNGBDBM3003(1,3-diphenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine |...)copy SMILEScopy InChI
Affinity DataIC50: 1.05E+3nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D2(Homo sapiens (Human))
University of Massachusetts Boston

LigandPNGBDBM50257541((1R,2R)-N-([S]-1-{4-[5-bromo-2-oxo-2,3-dihydro-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM123757(1,3-dimethyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine (...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D2(Homo sapiens (Human))
University of Massachusetts Boston

LigandPNGBDBM123756(1-methyl-3-(naphthalen-2-yl)-1H-pyrazolo[3,4-d]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D1(Homo sapiens (Human))
University of Massachusetts Boston

LigandPNGBDBM123749(1-(2-ethylphenyl)-3-(naphthalen-1-yl)-1H-pyrazolo[...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
Displayed 1 to 50 (of 65 total ) | Next | Last >>* indicates data uncertainty>20%