Compile Data Set for Download or QSAR

Found 29 hits of Enzyme Inhibition Constant Data   

TargetIntegrase(Human immunodeficiency virus 1)
Universit£ Lille Nord de France

Curated by ChEMBL
LigandPNGBDBM50017359(CHEMBL3288265)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of HIV-1 overall integrase activity using 5'-digoxigenin-labeled GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCAGT-3' as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ6335PubMed
TargetIntegrase(Human immunodeficiency virus 1)
Universit£ Lille Nord de France

Curated by ChEMBL
LigandPNGBDBM50017362(CHEMBL3288268)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of HIV-1 overall integrase activity using 5'-digoxigenin-labeled GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCAGT-3' as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ6335PubMed
TargetIntegrase(Human immunodeficiency virus 1)
Universit£ Lille Nord de France

Curated by ChEMBL
LigandPNGBDBM50017358(CHEMBL3286416)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of HIV-1 overall integrase activity using 5'-digoxigenin-labeled GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCAGT-3' as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ6335PubMed
TargetIntegrase(Human immunodeficiency virus 1)
Universit£ Lille Nord de France

Curated by ChEMBL
LigandPNGBDBM25351(N-[2-(4-{[(4-fluorophenyl)methyl]carbamoyl}-5-hydr...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of HIV-1 overall integrase activity using 5'-digoxigenin-labeled GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCAGT-3' as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ6335PubMedDrugBank
TargetIntegrase(Human immunodeficiency virus 1)
Universit£ Lille Nord de France

Curated by ChEMBL
LigandPNGBDBM50017364(CHEMBL3288273)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of HIV-1 overall integrase activity using 5'-digoxigenin-labeled GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCAGT-3' as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ6335PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Universit£ Lille Nord de France

Curated by ChEMBL
LigandPNGBDBM50410855(CIN-QUIN | QUINIDEX | QUINIDINE SULFATE)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant CYP2D6 (unknown origin) using 7-methoxy-4-trifluoromethylcoumarin as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ6335PubMed
TargetIntegrase(Human immunodeficiency virus 1)
Universit£ Lille Nord de France

Curated by ChEMBL
LigandPNGBDBM50017350(CHEMBL3288281)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of HIV-1 overall integrase activity using 5'-digoxigenin-labeled GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCAGT-3' as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ6335PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Universit£ Lille Nord de France

Curated by ChEMBL
LigandPNGBDBM50117930((4-{1-[2-(6-Methyl-pyridin-2-yl)-ethyl]-piperidine...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of human ERG tail current by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ6335PubMed
TargetIntegrase(Human immunodeficiency virus 1)
Universit£ Lille Nord de France

Curated by ChEMBL
LigandPNGBDBM50017365(CHEMBL3288274)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of HIV-1 overall integrase activity using 5'-digoxigenin-labeled GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCAGT-3' as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ6335PubMed
TargetIntegrase(Human immunodeficiency virus 1)
Universit£ Lille Nord de France

Curated by ChEMBL
LigandPNGBDBM50017360(CHEMBL3288266)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of HIV-1 overall integrase activity using 5'-digoxigenin-labeled GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCAGT-3' as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ6335PubMed
TargetIntegrase(Human immunodeficiency virus 1)
Universit£ Lille Nord de France

Curated by ChEMBL
LigandPNGBDBM50017356(CHEMBL3288263)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of HIV-1 overall integrase activity using 5'-digoxigenin-labeled GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCAGT-3' as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ6335PubMed
TargetIntegrase(Human immunodeficiency virus 1)
Universit£ Lille Nord de France

Curated by ChEMBL
LigandPNGBDBM50017361(CHEMBL3288267)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of HIV-1 overall integrase activity using 5'-digoxigenin-labeled GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCAGT-3' as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ6335PubMed
TargetIntegrase(Human immunodeficiency virus 1)
Universit£ Lille Nord de France

Curated by ChEMBL
LigandPNGBDBM50017357(CHEMBL3288264)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of HIV-1 overall integrase activity using 5'-digoxigenin-labeled GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCAGT-3' as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ6335PubMed
TargetIntegrase(Human immunodeficiency virus 1)
Universit£ Lille Nord de France

Curated by ChEMBL
LigandPNGBDBM50017349(CHEMBL3288280)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of HIV-1 overall integrase activity using 5'-digoxigenin-labeled GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCAGT-3' as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ6335PubMed
TargetIntegrase(Human immunodeficiency virus 1)
Universit£ Lille Nord de France

Curated by ChEMBL
LigandPNGBDBM50017351(CHEMBL3288282)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of HIV-1 overall integrase activity using 5'-digoxigenin-labeled GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCAGT-3' as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ6335PubMed
TargetIntegrase(Human immunodeficiency virus 1)
Universit£ Lille Nord de France

Curated by ChEMBL
LigandPNGBDBM50017353(CHEMBL3288271)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of HIV-1 overall integrase activity using 5'-digoxigenin-labeled GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCAGT-3' as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ6335PubMed
TargetIntegrase(Human immunodeficiency virus 1)
Universit£ Lille Nord de France

Curated by ChEMBL
LigandPNGBDBM50017352(CHEMBL3288270)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of HIV-1 overall integrase activity using 5'-digoxigenin-labeled GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCAGT-3' as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ6335PubMed
TargetIntegrase(Human immunodeficiency virus 1)
Universit£ Lille Nord de France

Curated by ChEMBL
LigandPNGBDBM50017366(CHEMBL3288275)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of HIV-1 overall integrase activity using 5'-digoxigenin-labeled GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCAGT-3' as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ6335PubMed
TargetIntegrase(Human immunodeficiency virus 1)
Universit£ Lille Nord de France

Curated by ChEMBL
LigandPNGBDBM50017348(CHEMBL3288279)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of HIV-1 overall integrase activity using 5'-digoxigenin-labeled GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCAGT-3' as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ6335PubMed
TargetIntegrase(Human immunodeficiency virus 1)
Universit£ Lille Nord de France

Curated by ChEMBL
LigandPNGBDBM50017354(CHEMBL3288261)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of HIV-1 overall integrase activity using 5'-digoxigenin-labeled GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCAGT-3' as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ6335PubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Universit£ Lille Nord de France

Curated by ChEMBL
LigandPNGBDBM50090677(4-Amino-N-(2-phenyl-2H-pyrazol-3-yl)-benzenesulfon...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of recombinant CYP2C9 (unknown origin) using 7-methoxy-4-trifluoromethylcoumarin as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ6335PubMedDrugBank
TargetIntegrase(Human immunodeficiency virus 1)
Universit£ Lille Nord de France

Curated by ChEMBL
LigandPNGBDBM50017355(CHEMBL3288262)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Inhibition of HIV-1 overall integrase activity using 5'-digoxigenin-labeled GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCAGT-3' as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ6335PubMed
TargetIntegrase(Human immunodeficiency virus 1)
Universit£ Lille Nord de France

Curated by ChEMBL
LigandPNGBDBM50017367(CHEMBL3288276)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Inhibition of HIV-1 overall integrase activity using 5'-digoxigenin-labeled GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCAGT-3' as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ6335PubMed
TargetIntegrase(Human immunodeficiency virus 1)
Universit£ Lille Nord de France

Curated by ChEMBL
LigandPNGBDBM50017368(CHEMBL3288277)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Inhibition of HIV-1 overall integrase activity using 5'-digoxigenin-labeled GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCAGT-3' as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ6335PubMed
TargetIntegrase(Human immunodeficiency virus 1)
Universit£ Lille Nord de France

Curated by ChEMBL
LigandPNGBDBM50017363(CHEMBL3288272)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Inhibition of HIV-1 overall integrase activity using 5'-digoxigenin-labeled GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCAGT-3' as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ6335PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Universit£ Lille Nord de France

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Inhibition of recombinant CYP3A4 (unknown origin) using 7-benzyloxy-4-trifluoromethylcoumarin as substrateMore data for this Ligand-Target Pair
TargetIntegrase(Human immunodeficiency virus 1)
Universit£ Lille Nord de France

Curated by ChEMBL
LigandPNGBDBM50017369(CHEMBL3288278)copy SMILEScopy InChI
Affinity DataIC50: 880nMAssay Description:Inhibition of HIV-1 overall integrase activity using 5'-digoxigenin-labeled GACCCTTTTAGTCAGTGTGGAAAATCTCTAGCAGT-3' as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ6335PubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Universit£ Lille Nord de France

Curated by ChEMBL
LigandPNGBDBM50236897(3-(furan-2-ylmethyl)-1,8-dimethyl-1H-purine-2,6(3H...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of recombinant CYP1A2 (unknown origin) using 7-ethoxy-3-cyanocoumarin as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ6335PubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Universit£ Lille Nord de France

Curated by ChEMBL
LigandPNGBDBM50113851((+/-)-Tranylcypromine | 2-PCPA | 2-Phenyl-cyclopro...)copy SMILEScopy InChI
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of recombinant CYP2C19 (unknown origin) using 7-ethoxy-3-cyanocoumarin as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ6335PubMed
* indicates data uncertainty>20%