Compile Data Set for Download or QSAR

Found 6 hits of Enzyme Inhibition Constant Data   

TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50017421(CHEMBL3288290)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Displacement of [125I]-hCGRP from CGRP receptor in human SK-N-MC cell membranes after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q241S2PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50017370(CHEMBL3288289)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Displacement of [125I]-hCGRP from CGRP receptor in human SK-N-MC cell membranes after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q241S2PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50017421(CHEMBL3288290)copy SMILEScopy InChI
Affinity DataEC50:  100nMAssay Description:Antagonist activity at CGRP receptor in human SK-N-MC cells assessed as inhibition of alpha-CGRP-induced c-AMP formation after 15 mins by radioimmuno...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q241S2PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50184069(CHEMBL207197 | N-((R)-1-((S)-6-amino-1-oxo-1-(4-(p...)copy SMILEScopy InChI
Affinity DataEC50:  0.0260nMAssay Description:Antagonist activity at CGRP receptor in human SK-N-MC cells assessed as inhibition of alpha-CGRP-induced c-AMP formation after 15 mins by radioimmuno...More data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50017422(CHEMBL3288288)copy SMILEScopy InChI
Affinity DataEC50:  0.150nMAssay Description:Antagonist activity at CGRP receptor in human SK-N-MC cells assessed as inhibition of alpha-CGRP-induced c-AMP formation after 15 mins by radioimmuno...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q241S2PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50017370(CHEMBL3288289)copy SMILEScopy InChI
Affinity DataEC50:  96nMAssay Description:Antagonist activity at CGRP receptor in human SK-N-MC cells assessed as inhibition of alpha-CGRP-induced c-AMP formation after 15 mins by radioimmuno...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q241S2PubMed
* indicates data uncertainty>20%