Found 35 hits of Enzyme Inhibition Constant Data
TargetCannabinoid receptor 2(Homo sapiens (Human))
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
Affinity DataKi: 0.450nM ΔG°: -54.2kJ/molepH: 7.4 T: 2°CAssay Description:In this assay, 18 ug of crude membrane expressing hCB1 or hCB2 receptors were re-suspended in 300 uL of binding buffer containing 50 mM Tris-HCl, 2.5...More data for this Ligand-Target Pair
3D Structure (crystal)TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
Affinity DataKi: 7.5nM ΔG°: -47.2kJ/molepH: 7.4 T: 2°CAssay Description:In this assay, 18 ug of crude membrane expressing hCB1 or hCB2 receptors were re-suspended in 300 uL of binding buffer containing 50 mM Tris-HCl, 2.5...More data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
Affinity DataKi: 13nM ΔG°: -45.8kJ/molepH: 7.4 T: 2°CAssay Description:In this assay, 18 ug of crude membrane expressing hCB1 or hCB2 receptors were re-suspended in 300 uL of binding buffer containing 50 mM Tris-HCl, 2.5...More data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
Affinity DataKi: 680nM ΔG°: -35.8kJ/molepH: 7.4 T: 2°CAssay Description:In this assay, 18 ug of crude membrane expressing hCB1 or hCB2 receptors were re-suspended in 300 uL of binding buffer containing 50 mM Tris-HCl, 2.5...More data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
Affinity DataKi: 1.01E+3nM ΔG°: -34.8kJ/molepH: 7.4 T: 2°CAssay Description:In this assay, 18 ug of crude membrane expressing hCB1 or hCB2 receptors were re-suspended in 300 uL of binding buffer containing 50 mM Tris-HCl, 2.5...More data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
Affinity DataKi: 1.43E+3nM ΔG°: -33.9kJ/molepH: 7.4 T: 2°CAssay Description:In this assay, 18 ug of crude membrane expressing hCB1 or hCB2 receptors were re-suspended in 300 uL of binding buffer containing 50 mM Tris-HCl, 2.5...More data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
Affinity DataKi: 3.66E+3nM ΔG°: -31.6kJ/molepH: 7.4 T: 2°CAssay Description:In this assay, 18 ug of crude membrane expressing hCB1 or hCB2 receptors were re-suspended in 300 uL of binding buffer containing 50 mM Tris-HCl, 2.5...More data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
Affinity DataKi: 3.83E+3nM ΔG°: -31.4kJ/molepH: 7.4 T: 2°CAssay Description:In this assay, 18 ug of crude membrane expressing hCB1 or hCB2 receptors were re-suspended in 300 uL of binding buffer containing 50 mM Tris-HCl, 2.5...More data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
Affinity DataKi: 6.50E+3nM ΔG°: -30.1kJ/molepH: 7.4 T: 2°CAssay Description:In this assay, 18 ug of crude membrane expressing hCB1 or hCB2 receptors were re-suspended in 300 uL of binding buffer containing 50 mM Tris-HCl, 2.5...More data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
Affinity DataKi: 8.64E+3nM ΔG°: -29.4kJ/molepH: 7.4 T: 2°CAssay Description:In this assay, 18 ug of crude membrane expressing hCB1 or hCB2 receptors were re-suspended in 300 uL of binding buffer containing 50 mM Tris-HCl, 2.5...More data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
Affinity DataKi: >1.00E+4nM ΔG°: >-29.0kJ/molepH: 7.4 T: 2°CAssay Description:In this assay, 18 ug of crude membrane expressing hCB1 or hCB2 receptors were re-suspended in 300 uL of binding buffer containing 50 mM Tris-HCl, 2.5...More data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
Affinity DataKi: >1.00E+4nM ΔG°: >-29.0kJ/molepH: 7.4 T: 2°CAssay Description:In this assay, 18 ug of crude membrane expressing hCB1 or hCB2 receptors were re-suspended in 300 uL of binding buffer containing 50 mM Tris-HCl, 2.5...More data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
Affinity DataKi: >1.00E+4nM ΔG°: >-29.0kJ/molepH: 7.4 T: 2°CAssay Description:In this assay, 18 ug of crude membrane expressing hCB1 or hCB2 receptors were re-suspended in 300 uL of binding buffer containing 50 mM Tris-HCl, 2.5...More data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
Affinity DataKi: >1.00E+4nM ΔG°: >-29.0kJ/molepH: 7.4 T: 2°CAssay Description:In this assay, 18 ug of crude membrane expressing hCB1 or hCB2 receptors were re-suspended in 300 uL of binding buffer containing 50 mM Tris-HCl, 2.5...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
Affinity DataIC50: 1.20nMpH: 7.6 T: 2°CAssay Description:In this assay, 0.05 Units of hFAAH was pre-incubated for 30 min at 37 C with 2 uL of 11a, 11b, 11f at different concentrations (0.01 - 100 uM) or veh...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
Affinity DataIC50: 68nMpH: 8.0 T: 2°CAssay Description:Tested compounds (50 uM), DuP-597 (0.5 uM; positive control), 11f and 11eie(1 nM - 200 uM ) or vehicle were pre-incubated with COX-FIS assay buffer (...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
Affinity DataIC50: 71nMpH: 8.0 T: 2°CAssay Description:Tested compounds (50 uM), DuP-597 (0.5 uM; positive control), 11f and 11eie(1 nM - 200 uM ) or vehicle were pre-incubated with COX-FIS assay buffer (...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
Affinity DataIC50: 800nMpH: 8.0 T: 2°CAssay Description:Tested compounds (50 uM), DuP-597 (0.5 uM; positive control), 11f and 11eie(1 nM - 200 uM ) or vehicle were pre-incubated with COX-FIS assay buffer (...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
Affinity DataIC50: 2.20E+3nMpH: 8.0 T: 2°CAssay Description:Tested compounds (50 uM), DuP-597 (0.5 uM; positive control), 11f and 11eie(1 nM - 200 uM ) or vehicle were pre-incubated with COX-FIS assay buffer (...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
Affinity DataIC50: 2.70E+3nMpH: 7.6 T: 2°CAssay Description:In this assay, 0.05 Units of hFAAH was pre-incubated for 30 min at 37 C with 2 uL of 11a, 11b, 11f at different concentrations (0.01 - 100 uM) or veh...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
Affinity DataIC50: 6.30E+3nMpH: 7.6 T: 2°CAssay Description:In this assay, 0.05 Units of hFAAH was pre-incubated for 30 min at 37 C with 2 uL of 11a, 11b, 11f at different concentrations (0.01 - 100 uM) or veh...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
Affinity DataIC50: 7.10E+3nMpH: 7.6 T: 2°CAssay Description:In this assay, 0.05 Units of hFAAH was pre-incubated for 30 min at 37 C with 2 uL of 11a, 11b, 11f at different concentrations (0.01 - 100 uM) or veh...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
Affinity DataIC50: 8.90E+3nMpH: 8.0 T: 2°CAssay Description:Tested compounds (50 uM), DuP-597 (0.5 uM; positive control), 11f and 11eie(1 nM - 200 uM ) or vehicle were pre-incubated with COX-FIS assay buffer (...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
Affinity DataIC50: 1.00E+4nMpH: 7.6 T: 2°CAssay Description:In this assay, 0.05 Units of hFAAH was pre-incubated for 30 min at 37 C with 2 uL of 11a, 11b, 11f at different concentrations (0.01 - 100 uM) or veh...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
Affinity DataIC50: 1.00E+4nMpH: 7.6 T: 2°CAssay Description:In this assay, 0.05 Units of hFAAH was pre-incubated for 30 min at 37 C with 2 uL of 11a, 11b, 11f at different concentrations (0.01 - 100 uM) or veh...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
Affinity DataIC50: 1.00E+4nMpH: 7.6 T: 2°CAssay Description:In this assay, 0.05 Units of hFAAH was pre-incubated for 30 min at 37 C with 2 uL of 11a, 11b, 11f at different concentrations (0.01 - 100 uM) or veh...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
Affinity DataIC50: 1.45E+4nMpH: 8.0 T: 2°CAssay Description:Tested compounds (50 uM), DuP-597 (0.5 uM; positive control), 11f and 11eie(1 nM - 200 uM ) or vehicle were pre-incubated with COX-FIS assay buffer (...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
Affinity DataIC50: 5.00E+4nMpH: 8.0 T: 2°CAssay Description:Tested compounds (50 uM), DuP-597 (0.5 uM; positive control), 11f and 11eie(1 nM - 200 uM ) or vehicle were pre-incubated with COX-FIS assay buffer (...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
Affinity DataIC50: 5.00E+4nMpH: 8.0 T: 2°CAssay Description:Tested compounds (50 uM), DuP-597 (0.5 uM; positive control), 11f and 11eie(1 nM - 200 uM ) or vehicle were pre-incubated with COX-FIS assay buffer (...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
Affinity DataIC50: 5.00E+4nMpH: 8.0 T: 2°CAssay Description:Tested compounds (50 uM), DuP-597 (0.5 uM; positive control), 11f and 11eie(1 nM - 200 uM ) or vehicle were pre-incubated with COX-FIS assay buffer (...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
Affinity DataIC50: 5.00E+4nMpH: 8.0 T: 2°CAssay Description:Tested compounds (50 uM), DuP-597 (0.5 uM; positive control), 11f and 11eie(1 nM - 200 uM ) or vehicle were pre-incubated with COX-FIS assay buffer (...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
Affinity DataIC50: 5.00E+4nMpH: 8.0 T: 2°CAssay Description:Tested compounds (50 uM), DuP-597 (0.5 uM; positive control), 11f and 11eie(1 nM - 200 uM ) or vehicle were pre-incubated with COX-FIS assay buffer (...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
Affinity DataIC50: 5.00E+4nMpH: 8.0 T: 2°CAssay Description:Tested compounds (50 uM), DuP-597 (0.5 uM; positive control), 11f and 11eie(1 nM - 200 uM ) or vehicle were pre-incubated with COX-FIS assay buffer (...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
Affinity DataIC50: 5.00E+4nMpH: 8.0 T: 2°CAssay Description:Tested compounds (50 uM), DuP-597 (0.5 uM; positive control), 11f and 11eie(1 nM - 200 uM ) or vehicle were pre-incubated with COX-FIS assay buffer (...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.
Affinity DataIC50: 5.00E+4nMpH: 8.0 T: 2°CAssay Description:Tested compounds (50 uM), DuP-597 (0.5 uM; positive control), 11f and 11eie(1 nM - 200 uM ) or vehicle were pre-incubated with COX-FIS assay buffer (...More data for this Ligand-Target Pair
