Compile Data Set for Download or QSAR

Found 10 hits of Enzyme Inhibition Constant Data   

TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50211642(CHEMBL397209 | Methyl(1,2,3,6-tetrahydropyridinium...)copy SMILEScopy InChI
Affinity DataIC50: 2.22E+3nMAssay Description:Antagonist activity at human recombinant GABAc rho-1 receptor expressed in Xenopus laevis oocytes assessed as inhibition of GABA-induced current by t...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50336851(3-(aminomethyl)-1-oxo-1-hydroxy-phospholane | CHEM...)copy SMILEScopy InChI
Affinity DataIC50: 1.99E+4nMAssay Description:Antagonist activity at human recombinant GABAc rho-1 receptor expressed in Xenopus laevis oocytes assessed as inhibition of GABA-induced current by t...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX79QRPubMed
TargetGamma-aminobutyric acid receptor subunit rho-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50211642(CHEMBL397209 | Methyl(1,2,3,6-tetrahydropyridinium...)copy SMILEScopy InChI
Affinity DataIC50: 2.21E+4nMAssay Description:Antagonist activity at human recombinant GABAc rho-2 receptor expressed in Xenopus laevis oocytes assessed as inhibition of GABA-induced current by t...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX79QRPubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50336850(3-(guanido)-1-oxo-1-hydroxy-phospholane | CHEMBL16...)copy SMILEScopy InChI
Affinity DataIC50: 2.97E+4nMAssay Description:Antagonist activity at human recombinant GABAc rho-1 receptor expressed in Xenopus laevis oocytes assessed as inhibition of GABA-induced current by t...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX79QRPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50032982((3-Amino-propyl)-butyl-phosphinic acid | 3-aminopr...)copy SMILEScopy InChI
Affinity DataIC50: 3.80E+4nMAssay Description:Antagonist activity at human recombinant GABAb 1b/2 receptor expressed in Xenopus laevis oocytes co-expressing GIRK1/4 assessed as inhibition of GABA...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX79QRPubMed
TargetGamma-aminobutyric acid receptor subunit rho-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50336850(3-(guanido)-1-oxo-1-hydroxy-phospholane | CHEMBL16...)copy SMILEScopy InChI
Affinity DataIC50: 5.13E+4nMAssay Description:Antagonist activity at human recombinant GABAc rho-2 receptor expressed in Xenopus laevis oocytes assessed as inhibition of GABA-induced current by t...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX79QRPubMed
TargetGamma-aminobutyric acid receptor subunit rho-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50336851(3-(aminomethyl)-1-oxo-1-hydroxy-phospholane | CHEM...)copy SMILEScopy InChI
Affinity DataIC50: 5.71E+4nMAssay Description:Antagonist activity at human recombinant GABAc rho-2 receptor expressed in Xenopus laevis oocytes assessed as inhibition of GABA-induced current by t...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX79QRPubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50032982((3-Amino-propyl)-butyl-phosphinic acid | 3-aminopr...)copy SMILEScopy InChI
Affinity DataIC50: 6.20E+4nMAssay Description:Antagonist activity at human recombinant GABAc rho-1 receptor expressed in Xenopus laevis oocytes assessed as inhibition of GABA-induced current by t...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX79QRPubMed
LigandPNGBDBM50032982((3-Amino-propyl)-butyl-phosphinic acid | 3-aminopr...)copy SMILEScopy InChI
Affinity DataIC50: 5.08E+5nMAssay Description:Antagonist activity at human recombinant GABAA alpha1beta2gamma2L receptor expressed in Xenopus laevis oocytes assessed as inhibition of GABA-induced...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX79QRPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50211642(CHEMBL397209 | Methyl(1,2,3,6-tetrahydropyridinium...)copy SMILEScopy InChI
Affinity DataEC50:  5.00E+5nMAssay Description:Antagonist activity at human recombinant GABAb 1b/2 receptor expressed in Xenopus laevis oocytes co-expressing GIRK1/4 assessed as inhibition of GABA...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX79QRPubMed
* indicates data uncertainty>20%