Compile Data Set for Download or QSAR

Found 28 hits of Enzyme Inhibition Constant Data   

TargetBombesin receptor subtype-3(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50336889((2S)-1,1,1-trifluoro-2-[4-(1H-pyrazol-1-yl)phenyl]...)copy SMILEScopy InChI
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]Bag-3 from rat BRS-3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5T81PubMed
TargetBombesin receptor subtype-3(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50336889((2S)-1,1,1-trifluoro-2-[4-(1H-pyrazol-1-yl)phenyl]...)copy SMILEScopy InChI
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]Bag-3 from rat BRS-3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5T81PubMed
TargetBombesin receptor subtype-3(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50336889((2S)-1,1,1-trifluoro-2-[4-(1H-pyrazol-1-yl)phenyl]...)copy SMILEScopy InChI
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]Bag-3 from mouse BRS-3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5T81PubMed
TargetBombesin receptor subtype-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50336889((2S)-1,1,1-trifluoro-2-[4-(1H-pyrazol-1-yl)phenyl]...)copy SMILEScopy InChI
Affinity DataKi:  3.70nMAssay Description:Displacement of [125I]-[D-Tyr6,beta-Ala11,Phe13,Nle14]-Bombesin (6-14) from human BRS-3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5T81PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50336886(1-[4-(2,2-dimethylpropyl)-1H-imidazol-2-yl]-2-[4-(...)copy SMILEScopy InChI
Affinity DataKi:  4.20E+3nMAssay Description:Binding affinity to human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5T81PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50336885(2-[4-(2,2-dimethylpropyl)-1H-imidazol-2-yl]-1-[4-(...)copy SMILEScopy InChI
Affinity DataKi:  5.90E+3nMAssay Description:Binding affinity to human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5T81PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50336889((2S)-1,1,1-trifluoro-2-[4-(1H-pyrazol-1-yl)phenyl]...)copy SMILEScopy InChI
Affinity DataKi: >8.00E+3nMAssay Description:Binding affinity to human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5T81PubMed
TargetBombesin receptor subtype-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50336887(1-[4-(2,2-dimethylpropyl)-1H-imidazol-2-yl]-2-[4-(...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Displacement of [125I]-[D-Tyr6,beta-Ala11,Phe13,Nle14]-Bombesin (6-14) from human BRS-3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5T81PubMed
TargetBombesin receptor subtype-3(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50336889((2S)-1,1,1-trifluoro-2-[4-(1H-pyrazol-1-yl)phenyl]...)copy SMILEScopy InChI
Affinity DataIC50: 5.40nMAssay Description:Displacement of [3H]Bag-3 from mouse BRS-3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5T81PubMed
TargetBombesin receptor subtype-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50336888(2-[4-(1H-pyrazol-1-yl)phenyl]-1-(4-{[1-(trifluorom...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Displacement of [125I]-[D-Tyr6,beta-Ala11,Phe13,Nle14]-Bombesin (6-14) from human BRS-3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5T81PubMed
TargetBombesin receptor subtype-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50314976(2-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)et...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Displacement of [125I]-[D-Tyr6,beta-Ala11,Phe13,Nle14]-Bombesin (6-14) from human BRS-3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5T81PubMed
TargetBombesin receptor subtype-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50336886(1-[4-(2,2-dimethylpropyl)-1H-imidazol-2-yl]-2-[4-(...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Displacement of [125I]-[D-Tyr6,beta-Ala11,Phe13,Nle14]-Bombesin (6-14) from human BRS-3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5T81PubMed
TargetBombesin receptor subtype-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50336885(2-[4-(2,2-dimethylpropyl)-1H-imidazol-2-yl]-1-[4-(...)copy SMILEScopy InChI
Affinity DataIC50: 82nMAssay Description:Displacement of [125I]-[D-Tyr6,beta-Ala11,Phe13,Nle14]-Bombesin (6-14) from human BRS-3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5T81PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50314969(2-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)et...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5T81PubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50314969(2-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)et...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+3nMAssay Description:Activation of human PXRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5T81PubMed
TargetGastrin-releasing peptide receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50336886(1-[4-(2,2-dimethylpropyl)-1H-imidazol-2-yl]-2-[4-(...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human GRPRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5T81PubMed
TargetNeuromedin-B receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50336886(1-[4-(2,2-dimethylpropyl)-1H-imidazol-2-yl]-2-[4-(...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human NMBRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5T81PubMed
TargetBombesin receptor subtype-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50313710(4'-(2-(5-butyl-1H-imidazol-2-yl)-5-hydroxypentyl)b...)copy SMILEScopy InChI
Affinity DataEC50:  1.90E+3nMAssay Description:Agonist activity at human BRS-3 expressed in HEK293AEQ cells assessed as induction of intracellular calcium mobilization by aequorin bioluminescence ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5T81PubMed
TargetBombesin receptor subtype-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50336888(2-[4-(1H-pyrazol-1-yl)phenyl]-1-(4-{[1-(trifluorom...)copy SMILEScopy InChI
Affinity DataEC50:  14nMAssay Description:Agonist activity at human BRS-3 expressed in HEK293AEQ cells assessed as induction of intracellular calcium mobilization by aequorin bioluminescence ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5T81PubMed
TargetBombesin receptor subtype-3(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50336889((2S)-1,1,1-trifluoro-2-[4-(1H-pyrazol-1-yl)phenyl]...)copy SMILEScopy InChI
Affinity DataEC50:  2.20nMAssay Description:Agonist activity at rat BRS-3 expressed in HEK293AEQ cells assessed as induction of intracellular calcium mobilization by aequorin bioluminescence as...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5T81PubMed
TargetBombesin receptor subtype-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50336889((2S)-1,1,1-trifluoro-2-[4-(1H-pyrazol-1-yl)phenyl]...)copy SMILEScopy InChI
Affinity DataEC50:  14nMAssay Description:Agonist activity at human BRS-3 expressed in HEK293AEQ cells assessed as induction of intracellular calcium mobilization by aequorin bioluminescence ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5T81PubMed
TargetBombesin receptor subtype-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50336887(1-[4-(2,2-dimethylpropyl)-1H-imidazol-2-yl]-2-[4-(...)copy SMILEScopy InChI
Affinity DataEC50:  16nMAssay Description:Agonist activity at human BRS-3 expressed in HEK293AEQ cells assessed as induction of intracellular calcium mobilization by aequorin bioluminescence ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5T81PubMed
TargetBombesin receptor subtype-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50314976(2-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)et...)copy SMILEScopy InChI
Affinity DataEC50:  66nMAssay Description:Agonist activity at human BRS-3 expressed in HEK293AEQ cells assessed as induction of intracellular calcium mobilization by aequorin bioluminescence ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5T81PubMed
TargetBombesin receptor subtype-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50336885(2-[4-(2,2-dimethylpropyl)-1H-imidazol-2-yl]-1-[4-(...)copy SMILEScopy InChI
Affinity DataEC50:  220nMAssay Description:Agonist activity at human BRS-3 expressed in HEK293AEQ cells assessed as induction of intracellular calcium mobilization by aequorin bioluminescence ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5T81PubMed
TargetBombesin receptor subtype-3(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50336889((2S)-1,1,1-trifluoro-2-[4-(1H-pyrazol-1-yl)phenyl]...)copy SMILEScopy InChI
Affinity DataEC50:  21nMAssay Description:Agonist activity at mouse BRS-3 expressed in HEK293AEQ cells assessed as induction of intracellular calcium mobilization by aequorin bioluminescence ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5T81PubMed
TargetBombesin receptor subtype-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50314969(2-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)et...)copy SMILEScopy InChI
Affinity DataEC50:  47nMAssay Description:Agonist activity at human BRS-3 expressed in HEK293AEQ cells assessed as induction of intracellular calcium mobilization by aequorin bioluminescence ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5T81PubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50336886(1-[4-(2,2-dimethylpropyl)-1H-imidazol-2-yl]-2-[4-(...)copy SMILEScopy InChI
Affinity DataEC50: >2.50E+4nMAssay Description:Activation of human PXRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5T81PubMed
TargetBombesin receptor subtype-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50336886(1-[4-(2,2-dimethylpropyl)-1H-imidazol-2-yl]-2-[4-(...)copy SMILEScopy InChI
Affinity DataEC50:  67nMAssay Description:Agonist activity at human BRS-3 expressed in HEK293AEQ cells assessed as induction of intracellular calcium mobilization by aequorin bioluminescence ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5T81PubMed
* indicates data uncertainty>20%