Compile Data Set for Download or QSAR

Found 22 hits of Enzyme Inhibition Constant Data   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50382388(CHEMBL2023973)copy SMILEScopy InChI
Affinity DataKi:  6nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N539ZPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50319665((S)-2-((1S,2S,4R)-Bicyclo[2.2.1]heptan-2-ylamino)-...)copy SMILEScopy InChI
Affinity DataKi:  12.8nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N539ZPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50382382(CHEMBL2023966)copy SMILEScopy InChI
Affinity DataKi:  16.5nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N539ZPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50382387(CHEMBL2023972)copy SMILEScopy InChI
Affinity DataKi:  17.5nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N539ZPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50382383(CHEMBL2023967)copy SMILEScopy InChI
Affinity DataKi:  17.9nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N539ZPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50382389(CHEMBL2023968)copy SMILEScopy InChI
Affinity DataKi:  23.5nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N539ZPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50382386(CHEMBL2023971)copy SMILEScopy InChI
Affinity DataKi:  27nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N539ZPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50382385(CHEMBL2023970)copy SMILEScopy InChI
Affinity DataKi:  37.3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N539ZPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50319665((S)-2-((1S,2S,4R)-Bicyclo[2.2.1]heptan-2-ylamino)-...)copy SMILEScopy InChI
Affinity DataKi:  70.8nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N539ZPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50382382(CHEMBL2023966)copy SMILEScopy InChI
Affinity DataKi:  152nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N539ZPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50382383(CHEMBL2023967)copy SMILEScopy InChI
Affinity DataKi:  181nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N539ZPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50382389(CHEMBL2023968)copy SMILEScopy InChI
Affinity DataKi:  230nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N539ZPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50382384(CHEMBL2023969)copy SMILEScopy InChI
Affinity DataKi:  449nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N539ZPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50319665((S)-2-((1S,2S,4R)-Bicyclo[2.2.1]heptan-2-ylamino)-...)copy SMILEScopy InChI
Affinity DataIC50: 10.1nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N539ZPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50382389(CHEMBL2023968)copy SMILEScopy InChI
Affinity DataIC50: 10.2nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N539ZPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50382382(CHEMBL2023966)copy SMILEScopy InChI
Affinity DataIC50: 12.7nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N539ZPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50382383(CHEMBL2023967)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N539ZPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50382388(CHEMBL2023973)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N539ZPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50382387(CHEMBL2023972)copy SMILEScopy InChI
Affinity DataIC50: 21.3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N539ZPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50382385(CHEMBL2023970)copy SMILEScopy InChI
Affinity DataIC50: 71.6nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N539ZPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50382386(CHEMBL2023971)copy SMILEScopy InChI
Affinity DataIC50: 87nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N539ZPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50382384(CHEMBL2023969)copy SMILEScopy InChI
Affinity DataIC50: 237nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N539ZPubMed
* indicates data uncertainty>20%