Compile Data Set for Download or QSAR

Found 39 hits of Enzyme Inhibition Constant Data   

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50049950(CHEMBL3317704)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in CHO cells after 45 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CF9PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50049938(CHEMBL3317701)copy SMILEScopy InChI
Affinity DataIC50: 7.70nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in CHO cells after 45 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CF9PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50049939(CHEMBL3317700)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in CHO cells after 45 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CF9PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50049936(CHEMBL3317703)copy SMILEScopy InChI
Affinity DataIC50: 9.20nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in CHO cells after 45 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CF9PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50049946(CHEMBL3317694)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in CHO cells after 45 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CF9PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50049937(CHEMBL3317702)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in CHO cells after 45 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CF9PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50049946(CHEMBL3317694)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in CHO cells after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CF9PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50049947(CHEMBL3353960)copy SMILEScopy InChI
Affinity DataIC50: 82nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in CHO cells after 45 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CF9PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50049950(CHEMBL3317704)copy SMILEScopy InChI
Affinity DataIC50: 83nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in CHO cells after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CF9PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50049936(CHEMBL3317703)copy SMILEScopy InChI
Affinity DataIC50: 88nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in CHO cells after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CF9PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50049947(CHEMBL3353960)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CF9PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50049936(CHEMBL3317703)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CF9PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50049950(CHEMBL3317704)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CF9PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50049938(CHEMBL3317701)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CF9PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50049937(CHEMBL3317702)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in CHO cells after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CF9PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50049945(CHEMBL3317695)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in CHO cells after 45 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CF9PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50049948(CHEMBL3317705)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in CHO cells after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CF9PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50049937(CHEMBL3317702)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CF9PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50049946(CHEMBL3317694)copy SMILEScopy InChI
Affinity DataIC50: 420nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CF9PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50049939(CHEMBL3317700)copy SMILEScopy InChI
Affinity DataIC50: 470nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CF9PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50049939(CHEMBL3317700)copy SMILEScopy InChI
Affinity DataIC50: 530nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in CHO cells after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CF9PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50049948(CHEMBL3317705)copy SMILEScopy InChI
Affinity DataIC50: 570nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in CHO cells after 45 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CF9PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50049938(CHEMBL3317701)copy SMILEScopy InChI
Affinity DataIC50: 570nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in CHO cells after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CF9PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50049943(CHEMBL3317697)copy SMILEScopy InChI
Affinity DataIC50: 660nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in CHO cells after 45 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CF9PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50049944(CHEMBL3317696)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in CHO cells after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CF9PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50049942(CHEMBL3317698)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in CHO cells after 45 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CF9PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50049943(CHEMBL3317697)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in CHO cells after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CF9PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50049944(CHEMBL3317696)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in CHO cells after 45 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CF9PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50049947(CHEMBL3353960)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in CHO cells after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CF9PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50049945(CHEMBL3317695)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in CHO cells after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CF9PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50049940(CHEMBL3317699)copy SMILEScopy InChI
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in CHO cells after 45 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CF9PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50049945(CHEMBL3317695)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CF9PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50049942(CHEMBL3317698)copy SMILEScopy InChI
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in CHO cells after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CF9PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50049943(CHEMBL3317697)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CF9PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50049940(CHEMBL3317699)copy SMILEScopy InChI
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in CHO cells after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CF9PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50049944(CHEMBL3317696)copy SMILEScopy InChI
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CF9PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50049940(CHEMBL3317699)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CF9PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50049942(CHEMBL3317698)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CF9PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50049948(CHEMBL3317705)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CF9PubMed
* indicates data uncertainty>20%