Compile Data Set for Download or QSAR

Found 24 hits of Enzyme Inhibition Constant Data   

TargetHistone deacetylase 1(Homo sapiens (Human))
University of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50051031(CHEMBL2158745)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human HDAC1 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93953PubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
University of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50051031(CHEMBL2158745)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human HDAC4 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93953PubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
University of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50309930(6-((1S,7R,10S,13R)-2,8,11,25-Tetraoxo-3,9,12,24-te...)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:Inhibition of human HDAC4 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93953PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50309930(6-((1S,7R,10S,13R)-2,8,11,25-Tetraoxo-3,9,12,24-te...)copy SMILEScopy InChI
Affinity DataIC50: 9.10nMAssay Description:Inhibition of human HDAC1 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93953PubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
University of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50309933(6-((5S,8R,11S,13aR)-4,7,10,13-Tetraoxo-5,8-dipenty...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of human HDAC4 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93953PubMed
TargetHistone deacetylase 6(Mus musculus)
University of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50051031(CHEMBL2158745)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of mouse HDAC6 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93953PubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
University of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50051035(CHEMBL3309858)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of human HDAC4 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93953PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50309933(6-((5S,8R,11S,13aR)-4,7,10,13-Tetraoxo-5,8-dipenty...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of human HDAC1 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93953PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50051033(CHEMBL3309856)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of human HDAC1 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93953PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50051034(CHEMBL3309857)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of human HDAC1 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93953PubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
University of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50051033(CHEMBL3309856)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of human HDAC4 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93953PubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
University of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50051034(CHEMBL3309857)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of human HDAC4 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93953PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50051032(CHEMBL3309855)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of human HDAC1 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93953PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50051035(CHEMBL3309858)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Inhibition of human HDAC1 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93953PubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
University of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50051032(CHEMBL3309855)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of human HDAC4 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93953PubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
University of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50051036(CHEMBL3356087)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Inhibition of human HDAC4 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93953PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50051036(CHEMBL3356087)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Inhibition of human HDAC1 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93953PubMed
TargetHistone deacetylase 6(Mus musculus)
University of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50051035(CHEMBL3309858)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of mouse HDAC6 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93953PubMed
TargetHistone deacetylase 6(Mus musculus)
University of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50051033(CHEMBL3309856)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Inhibition of mouse HDAC6 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93953PubMed
TargetHistone deacetylase 6(Mus musculus)
University of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50051032(CHEMBL3309855)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Inhibition of mouse HDAC6 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93953PubMed
TargetHistone deacetylase 6(Mus musculus)
University of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50309933(6-((5S,8R,11S,13aR)-4,7,10,13-Tetraoxo-5,8-dipenty...)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Inhibition of mouse HDAC6 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93953PubMed
TargetHistone deacetylase 6(Mus musculus)
University of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50309930(6-((1S,7R,10S,13R)-2,8,11,25-Tetraoxo-3,9,12,24-te...)copy SMILEScopy InChI
Affinity DataIC50: 410nMAssay Description:Inhibition of mouse HDAC6 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93953PubMed
TargetHistone deacetylase 6(Mus musculus)
University of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50051034(CHEMBL3309857)copy SMILEScopy InChI
Affinity DataIC50: 490nMAssay Description:Inhibition of mouse HDAC6 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93953PubMed
TargetHistone deacetylase 6(Mus musculus)
University of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50051036(CHEMBL3356087)copy SMILEScopy InChI
Affinity DataIC50: 570nMAssay Description:Inhibition of mouse HDAC6 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93953PubMed
* indicates data uncertainty>20%