Compile Data Set for Download or QSAR

Found 18 hits of Enzyme Inhibition Constant Data   

TargetHistone deacetylase 4(Homo sapiens (Human))
Kyushu Institute of Technology

LigandPNGBDBM152481(Z-L-Am7(betaMe)-QA (3))copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:For the enzyme assay, 10 無 of the enzyme fraction was added to 1 無 of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 無 of histone deacetylase...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T152C2PubMed
TargetHistone deacetylase 6(Mus musculus)
Kyushu Institute of Technology

LigandPNGBDBM152481(Z-L-Am7(betaMe)-QA (3))copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:For the enzyme assay, 10 無 of the enzyme fraction was added to 1 無 of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 無 of histone deacetylase...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T152C2PubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Kyushu Institute of Technology

LigandPNGBDBM152482((Z-L-Am7(S-)-QA)2 (4))copy SMILEScopy InChI
Affinity DataIC50: 3.40nMAssay Description:For the enzyme assay, 10 無 of the enzyme fraction was added to 1 無 of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 無 of histone deacetylase...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T152C2PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Kyushu Institute of Technology

LigandPNGBDBM152481(Z-L-Am7(betaMe)-QA (3))copy SMILEScopy InChI
Affinity DataIC50: 4.90nMAssay Description:For the enzyme assay, 10 無 of the enzyme fraction was added to 1 無 of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 無 of histone deacetylase...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T152C2PubMed
TargetHistone deacetylase 6(Mus musculus)
Kyushu Institute of Technology

LigandPNGBDBM152482((Z-L-Am7(S-)-QA)2 (4))copy SMILEScopy InChI
Affinity DataIC50: 7.5nMAssay Description:For the enzyme assay, 10 無 of the enzyme fraction was added to 1 無 of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 無 of histone deacetylase...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T152C2PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Kyushu Institute of Technology

LigandPNGBDBM152482((Z-L-Am7(S-)-QA)2 (4))copy SMILEScopy InChI
Affinity DataIC50: 8.20nMAssay Description:For the enzyme assay, 10 無 of the enzyme fraction was added to 1 無 of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 無 of histone deacetylase...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T152C2PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Kyushu Institute of Technology

LigandPNGBDBM50200895((S)-benzyl 8-(hydroxyamino)-1,8-dioxo-1-(quinolin-...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:For the enzyme assay, 10 無 of the enzyme fraction was added to 1 無 of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 無 of histone deacetylase...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T152C2PubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Kyushu Institute of Technology

LigandPNGBDBM50200895((S)-benzyl 8-(hydroxyamino)-1,8-dioxo-1-(quinolin-...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:For the enzyme assay, 10 無 of the enzyme fraction was added to 1 無 of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 無 of histone deacetylase...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T152C2PubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Kyushu Institute of Technology

LigandPNGBDBM152480(Z-L-Am7(AcEtMe)-QA (2))copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:For the enzyme assay, 10 無 of the enzyme fraction was added to 1 無 of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 無 of histone deacetylase...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T152C2PubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Kyushu Institute of Technology

LigandPNGBDBM152479(Z-L-Am7(Ac)-QA (1))copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:For the enzyme assay, 10 無 of the enzyme fraction was added to 1 無 of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 無 of histone deacetylase...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T152C2PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Kyushu Institute of Technology

LigandPNGBDBM152480(Z-L-Am7(AcEtMe)-QA (2))copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:For the enzyme assay, 10 無 of the enzyme fraction was added to 1 無 of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 無 of histone deacetylase...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T152C2PubMed
TargetHistone deacetylase 6(Mus musculus)
Kyushu Institute of Technology

LigandPNGBDBM152480(Z-L-Am7(AcEtMe)-QA (2))copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:For the enzyme assay, 10 無 of the enzyme fraction was added to 1 無 of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 無 of histone deacetylase...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T152C2PubMed
TargetHistone deacetylase 6(Mus musculus)
Kyushu Institute of Technology

LigandPNGBDBM152479(Z-L-Am7(Ac)-QA (1))copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:For the enzyme assay, 10 無 of the enzyme fraction was added to 1 無 of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 無 of histone deacetylase...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T152C2PubMed
TargetHistone deacetylase 6(Mus musculus)
Kyushu Institute of Technology

LigandPNGBDBM50200895((S)-benzyl 8-(hydroxyamino)-1,8-dioxo-1-(quinolin-...)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:For the enzyme assay, 10 無 of the enzyme fraction was added to 1 無 of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 無 of histone deacetylase...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T152C2PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Kyushu Institute of Technology

LigandPNGBDBM152479(Z-L-Am7(Ac)-QA (1))copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:For the enzyme assay, 10 無 of the enzyme fraction was added to 1 無 of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 無 of histone deacetylase...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T152C2PubMed
TargetHistone deacetylase 6(Mus musculus)
Kyushu Institute of Technology

LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:For the enzyme assay, 10 無 of the enzyme fraction was added to 1 無 of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 無 of histone deacetylase...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T152C2PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Kyushu Institute of Technology

LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 290nMAssay Description:For the enzyme assay, 10 無 of the enzyme fraction was added to 1 無 of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 無 of histone deacetylase...More data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Kyushu Institute of Technology

LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:For the enzyme assay, 10 無 of the enzyme fraction was added to 1 無 of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 無 of histone deacetylase...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T152C2PubMed
* indicates data uncertainty>20%