Found 72 hits of Enzyme Inhibition Constant Data
TargetThyrotropin-releasing hormone receptor(MOUSE)
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Displacement of [3H]-1-MeHis-TRH from mouse TRH-R1 expressed in HEK293 cells incubated up to 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(Mus musculus)
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Displacement of [3H]-1-MeHis-TRH from mouse TRH-R2 expressed in HEK293 cells incubated up to 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(Mus musculus)
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of [3H]-1-MeHis-TRH from mouse TRH-R2 expressed in HEK293 cells incubated up to 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(Mus musculus)
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of [3H]-1-MeHis-TRH from mouse TRH-R2 expressed in HEK293 cells incubated up to 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(MOUSE)
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of [3H]-1-MeHis-TRH from mouse TRH-R1 expressed in HEK293 cells incubated up to 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(MOUSE)
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of [3H]-1-MeHis-TRH from mouse TRH-R1 expressed in HEK293 cells incubated up to 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(Mus musculus)
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of [3H]-1-MeHis-TRH from mouse TRH-R2 expressed in HEK293 cells incubated up to 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(Mus musculus)
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of [3H]-1-MeHis-TRH from mouse TRH-R2 expressed in HEK293 cells incubated up to 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(Mus musculus)
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of [3H]-1-MeHis-TRH from mouse TRH-R2 expressed in HEK293 cells incubated up to 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(Mus musculus)
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of [3H]-1-MeHis-TRH from mouse TRH-R2 expressed in HEK293 cells incubated up to 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(Mus musculus)
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of [3H]-1-MeHis-TRH from mouse TRH-R2 expressed in HEK293 cells incubated up to 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(Mus musculus)
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of [3H]-1-MeHis-TRH from mouse TRH-R2 expressed in HEK293 cells incubated up to 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(Mus musculus)
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of [3H]-1-MeHis-TRH from mouse TRH-R2 expressed in HEK293 cells incubated up to 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(MOUSE)
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of [3H]-1-MeHis-TRH from mouse TRH-R1 expressed in HEK293 cells incubated up to 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(MOUSE)
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of [3H]-1-MeHis-TRH from mouse TRH-R1 expressed in HEK293 cells incubated up to 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(Mus musculus)
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of [3H]-1-MeHis-TRH from mouse TRH-R2 expressed in HEK293 cells incubated up to 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(Mus musculus)
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of [3H]-1-MeHis-TRH from mouse TRH-R2 expressed in HEK293 cells incubated up to 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(Mus musculus)
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of [3H]-1-MeHis-TRH from mouse TRH-R2 expressed in HEK293 cells incubated up to 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(Mus musculus)
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of [3H]-1-MeHis-TRH from mouse TRH-R2 expressed in HEK293 cells incubated up to 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(MOUSE)
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of [3H]-1-MeHis-TRH from mouse TRH-R1 expressed in HEK293 cells incubated up to 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(MOUSE)
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of [3H]-1-MeHis-TRH from mouse TRH-R1 expressed in HEK293 cells incubated up to 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(Mus musculus)
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of [3H]-1-MeHis-TRH from mouse TRH-R2 expressed in HEK293 cells incubated up to 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(Mus musculus)
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of [3H]-1-MeHis-TRH from mouse TRH-R2 expressed in HEK293 cells incubated up to 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(Mus musculus)
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of [3H]-1-MeHis-TRH from mouse TRH-R2 expressed in HEK293 cells incubated up to 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(Mus musculus)
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of [3H]-1-MeHis-TRH from mouse TRH-R2 expressed in HEK293 cells incubated up to 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(MOUSE)
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of [3H]-1-MeHis-TRH from mouse TRH-R1 expressed in HEK293 cells incubated up to 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(MOUSE)
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of [3H]-1-MeHis-TRH from mouse TRH-R1 expressed in HEK293 cells incubated up to 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(MOUSE)
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of [3H]-1-MeHis-TRH from mouse TRH-R1 expressed in HEK293 cells incubated up to 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(MOUSE)
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of [3H]-1-MeHis-TRH from mouse TRH-R1 expressed in HEK293 cells incubated up to 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(MOUSE)
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of [3H]-1-MeHis-TRH from mouse TRH-R1 expressed in HEK293 cells incubated up to 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(MOUSE)
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of [3H]-1-MeHis-TRH from mouse TRH-R1 expressed in HEK293 cells incubated up to 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(MOUSE)
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of [3H]-1-MeHis-TRH from mouse TRH-R1 expressed in HEK293 cells incubated up to 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(MOUSE)
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of [3H]-1-MeHis-TRH from mouse TRH-R1 expressed in HEK293 cells incubated up to 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(MOUSE)
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of [3H]-1-MeHis-TRH from mouse TRH-R1 expressed in HEK293 cells incubated up to 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(MOUSE)
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of [3H]-1-MeHis-TRH from mouse TRH-R1 expressed in HEK293 cells incubated up to 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(MOUSE)
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of [3H]-1-MeHis-TRH from mouse TRH-R1 expressed in HEK293 cells incubated up to 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(Mus musculus)
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataEC50: 290nMAssay Description:Agonist activity at mouse TRH-R2 expressed in HEK293 cells assessed as induction of changes in intracellular Ca2+ level by FLIPR methodMore data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(MOUSE)
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Agonist activity at mouse TRH-R1 expressed in HEK293 cells assessed as induction of changes in intracellular Ca2+ level by FLIPR methodMore data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(MOUSE)
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataEC50: 1.00E+3nMAssay Description:Agonist activity at mouse TRH-R1 expressed in HEK293 cells assessed as induction of changes in intracellular Ca2+ level by FLIPR methodMore data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(Mus musculus)
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataEC50: 100nMAssay Description:Agonist activity at mouse TRH-R2 expressed in HEK293 cells assessed as induction of changes in intracellular Ca2+ level by FLIPR methodMore data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(Mus musculus)
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataEC50: 310nMAssay Description:Agonist activity at mouse TRH-R2 expressed in HEK293 cells assessed as induction of changes in intracellular Ca2+ level by FLIPR methodMore data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(Mus musculus)
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataEC50: 4nMAssay Description:Agonist activity at mouse TRH-R2 expressed in HEK293 cells assessed as induction of changes in intracellular Ca2+ level by FLIPR methodMore data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(Mus musculus)
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataEC50: 0.520nMAssay Description:Agonist activity at mouse TRH-R2 expressed in HEK293 cells assessed as induction of changes in intracellular Ca2+ level by FLIPR methodMore data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(MOUSE)
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataEC50: 1.13E+4nMAssay Description:Agonist activity at mouse TRH-R1 expressed in HEK293 cells assessed as induction of changes in intracellular Ca2+ level by FLIPR methodMore data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(Mus musculus)
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataEC50: 530nMAssay Description:Agonist activity at mouse TRH-R2 expressed in HEK293 cells assessed as induction of changes in intracellular Ca2+ level by FLIPR methodMore data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(Mus musculus)
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataEC50: 50nMAssay Description:Agonist activity at mouse TRH-R2 expressed in HEK293 cells assessed as induction of changes in intracellular Ca2+ level by FLIPR methodMore data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(MOUSE)
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataEC50: 2.54E+3nMAssay Description:Agonist activity at mouse TRH-R1 expressed in HEK293 cells assessed as induction of changes in intracellular Ca2+ level by FLIPR methodMore data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(MOUSE)
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataEC50: 1.41E+3nMAssay Description:Agonist activity at mouse TRH-R1 expressed in HEK293 cells assessed as induction of changes in intracellular Ca2+ level by FLIPR methodMore data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(MOUSE)
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataEC50: 7.21E+3nMAssay Description:Agonist activity at mouse TRH-R1 expressed in HEK293 cells assessed as induction of changes in intracellular Ca2+ level by FLIPR methodMore data for this Ligand-Target Pair
TargetThyrotropin-releasing hormone receptor(Mus musculus)
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataEC50: 30nMAssay Description:Agonist activity at mouse TRH-R2 expressed in HEK293 cells assessed as induction of changes in intracellular Ca2+ level by FLIPR methodMore data for this Ligand-Target Pair