Compile Data Set for Download or QSAR

Found 26 hits of Enzyme Inhibition Constant Data   

TargetN-glycosylase/DNA lyase(Homo sapiens (Human))
Oregon Health & Science University

LigandPNGBDBM163679(3,4‐Dichloro‐1‐benzothiophene...)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Gel-based assays were performed by combining 4 無 of OGG1 (62.5 nM) with 1 無 of inhibitor or buffer. Substrate (5 無, 50 nM) was added to bring the ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7M6HPubMed
TargetN-glycosylase/DNA lyase(Homo sapiens (Human))
Oregon Health & Science University

LigandPNGBDBM163680(3‐Chloro‐N'‐[(1Z)‐2...)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:Gel-based assays were performed by combining 4 無 of OGG1 (62.5 nM) with 1 無 of inhibitor or buffer. Substrate (5 無, 50 nM) was added to bring the ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7M6HPubMed
TargetN-glycosylase/DNA lyase(Homo sapiens (Human))
Oregon Health & Science University

LigandPNGBDBM163683(N'‐Cyclohexylidene‐3‐hydroxy...)copy SMILEScopy InChI
Affinity DataIC50: 290nMpH: 7.5 T: 2°CAssay Description:A total of 4 無 of OGG1 (125 nM) was mixed with 1 無 of inhibitor. In a separate tube, 1 無 of freshly prepared 10 mM NaBH3CN (diluted in H2O) was mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7M6HPubMed
TargetN-glycosylase/DNA lyase(Homo sapiens (Human))
Oregon Health & Science University

LigandPNGBDBM163694(3‐Chloro‐1‐benzothiophene‐...)copy SMILEScopy InChI
Affinity DataIC50: 300nMpH: 7.5 T: 2°CAssay Description:A total of 4 無 of OGG1 (125 nM) was mixed with 1 無 of inhibitor. In a separate tube, 1 無 of freshly prepared 10 mM NaBH3CN (diluted in H2O) was mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7M6HPubMed
TargetN-glycosylase/DNA lyase(Homo sapiens (Human))
Oregon Health & Science University

LigandPNGBDBM163681(3-Chloro‐N'‐[(1E)‐(4‐f...)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:Gel-based assays were performed by combining 4 無 of OGG1 (62.5 nM) with 1 無 of inhibitor or buffer. Substrate (5 無, 50 nM) was added to bring the ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7M6HPubMed
TargetN-glycosylase/DNA lyase(Homo sapiens (Human))
Oregon Health & Science University

LigandPNGBDBM163683(N'‐Cyclohexylidene‐3‐hydroxy...)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Gel-based assays were performed by combining 4 無 of OGG1 (62.5 nM) with 1 無 of inhibitor or buffer. Substrate (5 無, 50 nM) was added to bring the ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7M6HPubMed
TargetN-glycosylase/DNA lyase(Homo sapiens (Human))
Oregon Health & Science University

LigandPNGBDBM163679(3,4‐Dichloro‐1‐benzothiophene...)copy SMILEScopy InChI
Affinity DataIC50: 350nMpH: 7.5 T: 2°CAssay Description:A total of 4 無 of OGG1 (125 nM) was mixed with 1 無 of inhibitor. In a separate tube, 1 無 of freshly prepared 10 mM NaBH3CN (diluted in H2O) was mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7M6HPubMed
TargetN-glycosylase/DNA lyase(Homo sapiens (Human))
Oregon Health & Science University

LigandPNGBDBM163680(3‐Chloro‐N'‐[(1Z)‐2...)copy SMILEScopy InChI
Affinity DataIC50: 370nMpH: 7.5 T: 2°CAssay Description:A total of 4 無 of OGG1 (125 nM) was mixed with 1 無 of inhibitor. In a separate tube, 1 無 of freshly prepared 10 mM NaBH3CN (diluted in H2O) was mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7M6HPubMed
TargetN-glycosylase/DNA lyase(Homo sapiens (Human))
Oregon Health & Science University

LigandPNGBDBM163695(Benzoylhydrazine, P‐bromo (0151-Hy))copy SMILEScopy InChI
Affinity DataIC50: 390nMpH: 7.5 T: 2°CAssay Description:A total of 4 無 of OGG1 (125 nM) was mixed with 1 無 of inhibitor. In a separate tube, 1 無 of freshly prepared 10 mM NaBH3CN (diluted in H2O) was mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7M6HPubMed
TargetN-glycosylase/DNA lyase(Homo sapiens (Human))
Oregon Health & Science University

LigandPNGBDBM163681(3-Chloro‐N'‐[(1E)‐(4‐f...)copy SMILEScopy InChI
Affinity DataIC50: 420nMpH: 7.5 T: 2°CAssay Description:A total of 4 無 of OGG1 (125 nM) was mixed with 1 無 of inhibitor. In a separate tube, 1 無 of freshly prepared 10 mM NaBH3CN (diluted in H2O) was mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7M6HPubMed
TargetN-glycosylase/DNA lyase(Homo sapiens (Human))
Oregon Health & Science University

LigandPNGBDBM163682(4‐Bromo‐N'‐cyclohexylidenebe...)copy SMILEScopy InChI
Affinity DataIC50: 610nMpH: 7.5 T: 2°CAssay Description:A total of 4 無 of OGG1 (125 nM) was mixed with 1 無 of inhibitor. In a separate tube, 1 無 of freshly prepared 10 mM NaBH3CN (diluted in H2O) was mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7M6HPubMed
TargetN-glycosylase/DNA lyase(Homo sapiens (Human))
Oregon Health & Science University

LigandPNGBDBM163682(4‐Bromo‐N'‐cyclohexylidenebe...)copy SMILEScopy InChI
Affinity DataIC50: 630nMAssay Description:Gel-based assays were performed by combining 4 無 of OGG1 (62.5 nM) with 1 無 of inhibitor or buffer. Substrate (5 無, 50 nM) was added to bring the ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7M6HPubMed
TargetN-glycosylase/DNA lyase(Homo sapiens (Human))
Oregon Health & Science University

LigandPNGBDBM163685(2‐(4‐Chloro‐3,5‐dimethylph...)copy SMILEScopy InChI
Affinity DataIC50: 1.53E+3nMpH: 7.5 T: 2°CAssay Description:A total of 4 無 of OGG1 (125 nM) was mixed with 1 無 of inhibitor. In a separate tube, 1 無 of freshly prepared 10 mM NaBH3CN (diluted in H2O) was mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7M6HPubMed
TargetN-glycosylase/DNA lyase(Homo sapiens (Human))
Oregon Health & Science University

LigandPNGBDBM163686(2‐(Naphthalen‐1‐yloxy)acetohydra...)copy SMILEScopy InChI
Affinity DataIC50: 1.56E+3nMpH: 7.5 T: 2°CAssay Description:A total of 4 無 of OGG1 (125 nM) was mixed with 1 無 of inhibitor. In a separate tube, 1 無 of freshly prepared 10 mM NaBH3CN (diluted in H2O) was mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7M6HPubMed
TargetN-glycosylase/DNA lyase(Homo sapiens (Human))
Oregon Health & Science University

LigandPNGBDBM163690(3‐Bromo‐N'‐[(2Z)‐hexan...)copy SMILEScopy InChI
Affinity DataIC50: 2.13E+3nMpH: 7.5 T: 2°CAssay Description:A total of 4 無 of OGG1 (125 nM) was mixed with 1 無 of inhibitor. In a separate tube, 1 無 of freshly prepared 10 mM NaBH3CN (diluted in H2O) was mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7M6HPubMed
TargetN-glycosylase/DNA lyase(Homo sapiens (Human))
Oregon Health & Science University

LigandPNGBDBM163684(2‐(3‐Chlorophenoxy)propanehydrazide (0...)copy SMILEScopy InChI
Affinity DataIC50: 3.38E+3nMpH: 7.5 T: 2°CAssay Description:A total of 4 無 of OGG1 (125 nM) was mixed with 1 無 of inhibitor. In a separate tube, 1 無 of freshly prepared 10 mM NaBH3CN (diluted in H2O) was mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7M6HPubMed
TargetN-glycosylase/DNA lyase(Homo sapiens (Human))
Oregon Health & Science University

LigandPNGBDBM163689(3‐Bromo‐N'‐[(2Z)‐hex&#...)copy SMILEScopy InChI
Affinity DataIC50: 3.78E+3nMpH: 7.5 T: 2°CAssay Description:A total of 4 無 of OGG1 (125 nM) was mixed with 1 無 of inhibitor. In a separate tube, 1 無 of freshly prepared 10 mM NaBH3CN (diluted in H2O) was mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7M6HPubMed
TargetN-glycosylase/DNA lyase(Homo sapiens (Human))
Oregon Health & Science University

LigandPNGBDBM163691(1‐(4‐Methoxy‐2,5‐dimethylb...)copy SMILEScopy InChI
Affinity DataIC50: 4.15E+3nMpH: 7.5 T: 2°CAssay Description:A total of 4 無 of OGG1 (125 nM) was mixed with 1 無 of inhibitor. In a separate tube, 1 無 of freshly prepared 10 mM NaBH3CN (diluted in H2O) was mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7M6HPubMed
TargetN-glycosylase/DNA lyase(Homo sapiens (Human))
Oregon Health & Science University

LigandPNGBDBM163688(2,4‐Dichloro‐N'‐(1‐pro...)copy SMILEScopy InChI
Affinity DataIC50: 4.56E+3nMpH: 7.5 T: 2°CAssay Description:A total of 4 無 of OGG1 (125 nM) was mixed with 1 無 of inhibitor. In a separate tube, 1 無 of freshly prepared 10 mM NaBH3CN (diluted in H2O) was mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7M6HPubMed
TargetN-glycosylase/DNA lyase(Homo sapiens (Human))
Oregon Health & Science University

LigandPNGBDBM163687(N'‐[(1E)‐1‐(2H‐1,3R...)copy SMILEScopy InChI
Affinity DataIC50: 7.17E+3nMpH: 7.5 T: 2°CAssay Description:A total of 4 無 of OGG1 (125 nM) was mixed with 1 無 of inhibitor. In a separate tube, 1 無 of freshly prepared 10 mM NaBH3CN (diluted in H2O) was mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7M6HPubMed
TargetN-glycosylase/DNA lyase(Homo sapiens (Human))
Oregon Health & Science University

LigandPNGBDBM50336507(4-pyridinecarbohydrazide(Isoniazid) | CHEMBL64 | D...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMpH: 7.5 T: 2°CAssay Description:A total of 4 無 of OGG1 (125 nM) was mixed with 1 無 of inhibitor. In a separate tube, 1 無 of freshly prepared 10 mM NaBH3CN (diluted in H2O) was mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7M6HPubMed
TargetN-glycosylase/DNA lyase(Homo sapiens (Human))
Oregon Health & Science University

LigandPNGBDBM163692(ISOCARBOXAZID | Isocarboxazid (ICD) | Isocarboxazi...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMpH: 7.5 T: 2°CAssay Description:A total of 4 無 of OGG1 (125 nM) was mixed with 1 無 of inhibitor. In a separate tube, 1 無 of freshly prepared 10 mM NaBH3CN (diluted in H2O) was mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7M6HPubMed
TargetN-glycosylase/DNA lyase(Homo sapiens (Human))
Oregon Health & Science University

LigandPNGBDBM50336507(4-pyridinecarbohydrazide(Isoniazid) | CHEMBL64 | D...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Gel-based assays were performed by combining 4 無 of OGG1 (62.5 nM) with 1 無 of inhibitor or buffer. Substrate (5 無, 50 nM) was added to bring the ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7M6HPubMed
TargetN-glycosylase/DNA lyase(Homo sapiens (Human))
Oregon Health & Science University

LigandPNGBDBM81461(CAS_86-54-4 | Hydralazine | Hydralazine (HZN) | NS...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMpH: 7.5 T: 2°CAssay Description:A total of 4 無 of OGG1 (125 nM) was mixed with 1 無 of inhibitor. In a separate tube, 1 無 of freshly prepared 10 mM NaBH3CN (diluted in H2O) was mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7M6HPubMed
TargetN-glycosylase/DNA lyase(Homo sapiens (Human))
Oregon Health & Science University

LigandPNGBDBM50106186(4‐Bromobenzamide (0151-Am) | 4-Bromo-benzami...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMpH: 7.5 T: 2°CAssay Description:A total of 4 無 of OGG1 (125 nM) was mixed with 1 無 of inhibitor. In a separate tube, 1 無 of freshly prepared 10 mM NaBH3CN (diluted in H2O) was mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7M6HPubMed
TargetN-glycosylase/DNA lyase(Homo sapiens (Human))
Oregon Health & Science University

LigandPNGBDBM163693(Nialamide)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMpH: 7.5 T: 2°CAssay Description:A total of 4 無 of OGG1 (125 nM) was mixed with 1 無 of inhibitor. In a separate tube, 1 無 of freshly prepared 10 mM NaBH3CN (diluted in H2O) was mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7M6HPubMed
* indicates data uncertainty>20%