Compile Data Set for Download or QSAR

Found 64 hits of Enzyme Inhibition Constant Data   

TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121379(CHEMBL3622134)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of JAK2 (unknown origin) using 5-FAMKKKKEEIYFFFG-OH as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121378(CHEMBL3622135)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Inhibition of JAK2 (unknown origin) using 5-FAMKKKKEEIYFFFG-OH as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121377(CHEMBL3622136)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Inhibition of JAK2 (unknown origin) using 5-FAMKKKKEEIYFFFG-OH as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121391(CHEMBL3622137)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of JAK2 (unknown origin) using 5-FAMKKKKEEIYFFFG-OH as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121383(CHEMBL3622130)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Inhibition of JAK2 (unknown origin) using 5-FAMKKKKEEIYFFFG-OH as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121385(CHEMBL3622128)copy SMILEScopy InChI
Affinity DataIC50: 4.5nMAssay Description:Inhibition of JAK2 (unknown origin) using 5-FAMKKKKEEIYFFFG-OH as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121390(CHEMBL3622138)copy SMILEScopy InChI
Affinity DataIC50: 7.80nMAssay Description:Inhibition of JAK2 (unknown origin) using 5-FAMKKKKEEIYFFFG-OH as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121386(CHEMBL3622127)copy SMILEScopy InChI
Affinity DataIC50: 8.20nMAssay Description:Inhibition of JAK2 (unknown origin) using 5-FAMKKKKEEIYFFFG-OH as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121391(CHEMBL3622137)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant Fyn (unknown origin) using fluoresceinated peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121380(CHEMBL3622133)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of JAK2 (unknown origin) using 5-FAMKKKKEEIYFFFG-OH as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121384(CHEMBL3622129)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of JAK2 (unknown origin) using 5-FAMKKKKEEIYFFFG-OH as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121379(CHEMBL3622134)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of JAK2 in human SET2 cells assessed as inhibition of cell proliferation after 72 hrs by [3H]-thymidine incorporation assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121378(CHEMBL3622135)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant JAK3 (unknown origin) using fluoresceinated peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121377(CHEMBL3622136)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of JAK2 in human SET2 cells assessed as inhibition of cell proliferation after 72 hrs by [3H]-thymidine incorporation assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121381(CHEMBL3622132)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of JAK2 (unknown origin) using 5-FAMKKKKEEIYFFFG-OH as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121379(CHEMBL3622134)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of recombinant Tyk2 (unknown origin) using fluoresceinated peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121382(CHEMBL3622131)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of JAK2 (unknown origin) using 5-FAMKKKKEEIYFFFG-OH as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121379(CHEMBL3622134)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant JAK1 (unknown origin) using fluoresceinated peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121388(CHEMBL3622140)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Inhibition of JAK2 (unknown origin) using 5-FAMKKKKEEIYFFFG-OH as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121378(CHEMBL3622135)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Inhibition of recombinant Tyk2 (unknown origin) using fluoresceinated peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121377(CHEMBL3622136)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Inhibition of recombinant Tyk2 (unknown origin) using fluoresceinated peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121378(CHEMBL3622135)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Inhibition of recombinant JAK1 (unknown origin) using fluoresceinated peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121377(CHEMBL3622136)copy SMILEScopy InChI
Affinity DataIC50: 61nMAssay Description:Inhibition of recombinant JAK1 (unknown origin) using fluoresceinated peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121379(CHEMBL3622134)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Inhibition of recombinant JAK3 (unknown origin) using fluoresceinated peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121383(CHEMBL3622130)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:Inhibition of recombinant JAK1 (unknown origin) using fluoresceinated peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121391(CHEMBL3622137)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:Inhibition of JAK2 in human SET2 cells assessed as inhibition of cell proliferation after 72 hrs by [3H]-thymidine incorporation assayMore data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121383(CHEMBL3622130)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant Tyk2 (unknown origin) using fluoresceinated peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121378(CHEMBL3622135)copy SMILEScopy InChI
Affinity DataIC50: 73nMAssay Description:Inhibition of JAK2 in human SET2 cells assessed as inhibition of cell proliferation after 72 hrs by [3H]-thymidine incorporation assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121377(CHEMBL3622136)copy SMILEScopy InChI
Affinity DataIC50: 77nMAssay Description:Inhibition of recombinant JAK3 (unknown origin) using fluoresceinated peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121391(CHEMBL3622137)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant Tyk2 (unknown origin) using fluoresceinated peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121385(CHEMBL3622128)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of recombinant JAK3 (unknown origin) using fluoresceinated peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121391(CHEMBL3622137)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of recombinant JAK3 (unknown origin) using fluoresceinated peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121383(CHEMBL3622130)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Inhibition of recombinant JAK3 (unknown origin) using fluoresceinated peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121390(CHEMBL3622138)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant JAK3 (unknown origin) using fluoresceinated peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121380(CHEMBL3622133)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Inhibition of JAK2 in human SET2 cells assessed as inhibition of cell proliferation after 72 hrs by [3H]-thymidine incorporation assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121380(CHEMBL3622133)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibition of recombinant JAK1 (unknown origin) using fluoresceinated peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121386(CHEMBL3622127)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Inhibition of recombinant JAK3 (unknown origin) using fluoresceinated peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121391(CHEMBL3622137)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:Inhibition of recombinant JAK1 (unknown origin) using fluoresceinated peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121380(CHEMBL3622133)copy SMILEScopy InChI
Affinity DataIC50: 290nMAssay Description:Inhibition of recombinant Tyk2 (unknown origin) using fluoresceinated peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121383(CHEMBL3622130)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Inhibition of JAK2 in human SET2 cells assessed as inhibition of cell proliferation after 72 hrs by [3H]-thymidine incorporation assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121384(CHEMBL3622129)copy SMILEScopy InChI
Affinity DataIC50: 370nMAssay Description:Inhibition of JAK2 in human SET2 cells assessed as inhibition of cell proliferation after 72 hrs by [3H]-thymidine incorporation assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121385(CHEMBL3622128)copy SMILEScopy InChI
Affinity DataIC50: 390nMAssay Description:Inhibition of JAK2 in human SET2 cells assessed as inhibition of cell proliferation after 72 hrs by [3H]-thymidine incorporation assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121387(CHEMBL3622141)copy SMILEScopy InChI
Affinity DataIC50: 450nMAssay Description:Inhibition of JAK2 (unknown origin) using 5-FAMKKKKEEIYFFFG-OH as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121380(CHEMBL3622133)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant JAK3 (unknown origin) using fluoresceinated peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121384(CHEMBL3622129)copy SMILEScopy InChI
Affinity DataIC50: 510nMAssay Description:Inhibition of recombinant JAK3 (unknown origin) using fluoresceinated peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121389(CHEMBL3622139)copy SMILEScopy InChI
Affinity DataIC50: 570nMAssay Description:Inhibition of JAK2 (unknown origin) using 5-FAMKKKKEEIYFFFG-OH as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121381(CHEMBL3622132)copy SMILEScopy InChI
Affinity DataIC50: 580nMAssay Description:Inhibition of JAK2 in human SET2 cells assessed as inhibition of cell proliferation after 72 hrs by [3H]-thymidine incorporation assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121388(CHEMBL3622140)copy SMILEScopy InChI
Affinity DataIC50: 670nMAssay Description:Inhibition of recombinant JAK3 (unknown origin) using fluoresceinated peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121382(CHEMBL3622131)copy SMILEScopy InChI
Affinity DataIC50: 690nMAssay Description:Inhibition of recombinant Tyk2 (unknown origin) using fluoresceinated peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121386(CHEMBL3622127)copy SMILEScopy InChI
Affinity DataIC50: 720nMAssay Description:Inhibition of JAK2 in human SET2 cells assessed as inhibition of cell proliferation after 72 hrs by [3H]-thymidine incorporation assayMore data for this Ligand-Target Pair
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