Compile Data Set for Download or QSAR

Found 25 hits of Enzyme Inhibition Constant Data   

TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human PDGFRbeta by kinase inhibition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G162MGPubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 4.90nMAssay Description:Inhibition of human CDK1 by kinase inhibition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G162MGPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 9.70nMAssay Description:Inhibition of human Src kinase by kinase inhibition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G162MGPubMed
TargetAurora kinase A(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of human AurA kinase by kinase inhibition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G162MGPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of human Akt1 by kinase inhibition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G162MGPubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of human ROCK1 by kinase inhibition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G162MGPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of EGFR (unknown origin) using omnia tyr peptide 7 substrate by fluorescence assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of human MEK1 by kinase inhibition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G162MGPubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 55nMAssay Description:Inhibition of human FAK by kinase inhibition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G162MGPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of human RAF1 by kinase inhibition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G162MGPubMed
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human ERK1 by kinase inhibition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G162MGPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50126847(CHEMBL3628537)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human KDR incubated for 50 mins by omnia tyr peptide 8 substrate based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G162MGPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50126846(CHEMBL481789)copy SMILEScopy InChI
Affinity DataIC50: 4.72E+3nMAssay Description:Inhibition of EGFR (unknown origin) using omnia tyr peptide 7 substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G162MGPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50126850(CHEMBL3628818)copy SMILEScopy InChI
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human KDR incubated for 50 mins by omnia tyr peptide 8 substrate based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G162MGPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50126851(CHEMBL3628536)copy SMILEScopy InChI
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of human KDR incubated for 50 mins by omnia tyr peptide 8 substrate based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G162MGPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM4810((3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-...)copy SMILEScopy InChI
Affinity DataIC50: 1.29E+4nMAssay Description:Inhibition of human KDR incubated for 50 mins by omnia tyr peptide 8 substrate based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G162MGPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50126845(CHEMBL3628814)copy SMILEScopy InChI
Affinity DataIC50: 1.75E+4nMAssay Description:Inhibition of human KDR incubated for 50 mins by omnia tyr peptide 8 substrate based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G162MGPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50126848(CHEMBL3628816)copy SMILEScopy InChI
Affinity DataIC50: 2.12E+4nMAssay Description:Inhibition of EGFR (unknown origin) using omnia tyr peptide 7 substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G162MGPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50126852(CHEMBL3628817)copy SMILEScopy InChI
Affinity DataIC50: 2.16E+4nMAssay Description:Inhibition of EGFR (unknown origin) using omnia tyr peptide 7 substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G162MGPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50126850(CHEMBL3628818)copy SMILEScopy InChI
Affinity DataIC50: 4.57E+4nMAssay Description:Inhibition of EGFR (unknown origin) using omnia tyr peptide 7 substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G162MGPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50126853(CHEMBL3628815)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human KDR incubated for 50 mins by omnia tyr peptide 8 substrate based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G162MGPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50126848(CHEMBL3628816)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human KDR incubated for 50 mins by omnia tyr peptide 8 substrate based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G162MGPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50126852(CHEMBL3628817)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human KDR incubated for 50 mins by omnia tyr peptide 8 substrate based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G162MGPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50126849(CHEMBL3628813)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human KDR incubated for 50 mins by omnia tyr peptide 8 substrate based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G162MGPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50126854(CHEMBL3628812)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human KDR incubated for 50 mins by omnia tyr peptide 8 substrate based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G162MGPubMed
* indicates data uncertainty>20%