Compile Data Set for Download or QSAR

Found 20 hits of Enzyme Inhibition Constant Data   

TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Qilu University of Technology

Curated by ChEMBL
LigandPNGBDBM50133021(CHEMBL3634592)copy SMILEScopy InChI
Affinity DataIC50: 222nMAssay Description:Inhibition of recombinant PTP1B (unknown origin) assessed as hydrolysis of pNPP to pNP after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2CTVPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Qilu University of Technology

Curated by ChEMBL
LigandPNGBDBM50133000(CHEMBL3634591)copy SMILEScopy InChI
Affinity DataIC50: 346nMAssay Description:Inhibition of recombinant PTP1B (unknown origin) assessed as hydrolysis of pNPP to pNP after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2CTVPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Qilu University of Technology

Curated by ChEMBL
LigandPNGBDBM50133031(CHEMBL3634683)copy SMILEScopy InChI
Affinity DataIC50: 470nMAssay Description:Inhibition of recombinant PTP1B (unknown origin) assessed as hydrolysis of pNPP to pNP after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2CTVPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Qilu University of Technology

Curated by ChEMBL
LigandPNGBDBM50133030(CHEMBL3634681)copy SMILEScopy InChI
Affinity DataIC50: 492nMAssay Description:Inhibition of recombinant PTP1B (unknown origin) assessed as hydrolysis of pNPP to pNP after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2CTVPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Qilu University of Technology

Curated by ChEMBL
LigandPNGBDBM50133028(CHEMBL3634594)copy SMILEScopy InChI
Affinity DataIC50: 896nMAssay Description:Inhibition of recombinant PTP1B (unknown origin) assessed as hydrolysis of pNPP to pNP after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2CTVPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Qilu University of Technology

Curated by ChEMBL
LigandPNGBDBM50133027(CHEMBL3634593)copy SMILEScopy InChI
Affinity DataIC50: 902nMAssay Description:Inhibition of recombinant PTP1B (unknown origin) assessed as hydrolysis of pNPP to pNP after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2CTVPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Qilu University of Technology

Curated by ChEMBL
LigandPNGBDBM50346601(NSC-114945 | OLEANOLIC_ACID | Oleanolic acid | Ole...)copy SMILEScopy InChI
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibition of recombinant PTP1B (unknown origin) assessed as hydrolysis of pNPP to pNP after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2CTVPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Qilu University of Technology

Curated by ChEMBL
LigandPNGBDBM50133032(CHEMBL3634684)copy SMILEScopy InChI
Affinity DataIC50: 1.71E+3nMAssay Description:Inhibition of recombinant PTP1B (unknown origin) assessed as hydrolysis of pNPP to pNP after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2CTVPubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Qilu University of Technology

Curated by ChEMBL
LigandPNGBDBM50133021(CHEMBL3634592)copy SMILEScopy InChI
Affinity DataIC50: 1.86E+3nMAssay Description:Inhibition of TCPTP (unknown origin) assessed as hydrolysis of pNPP to pNP after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2CTVPubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Qilu University of Technology

Curated by ChEMBL
LigandPNGBDBM50133031(CHEMBL3634683)copy SMILEScopy InChI
Affinity DataIC50: 1.92E+3nMAssay Description:Inhibition of TCPTP (unknown origin) assessed as hydrolysis of pNPP to pNP after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2CTVPubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Qilu University of Technology

Curated by ChEMBL
LigandPNGBDBM50133021(CHEMBL3634592)copy SMILEScopy InChI
Affinity DataIC50: 2.31E+3nMAssay Description:Inhibition of SHP1 (unknown origin) assessed as hydrolysis of pNPP to pNP after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2CTVPubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Qilu University of Technology

Curated by ChEMBL
LigandPNGBDBM50346601(NSC-114945 | OLEANOLIC_ACID | Oleanolic acid | Ole...)copy SMILEScopy InChI
Affinity DataIC50: 5.46E+3nMAssay Description:Inhibition of TCPTP (unknown origin) assessed as hydrolysis of pNPP to pNP after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2CTVPubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Qilu University of Technology

Curated by ChEMBL
LigandPNGBDBM50133030(CHEMBL3634681)copy SMILEScopy InChI
Affinity DataIC50: 9.61E+3nMAssay Description:Inhibition of SHP1 (unknown origin) assessed as hydrolysis of pNPP to pNP after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2CTVPubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Qilu University of Technology

Curated by ChEMBL
LigandPNGBDBM50133031(CHEMBL3634683)copy SMILEScopy InChI
Affinity DataIC50: 1.14E+4nMAssay Description:Inhibition of SHP1 (unknown origin) assessed as hydrolysis of pNPP to pNP after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2CTVPubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Qilu University of Technology

Curated by ChEMBL
LigandPNGBDBM50391109(CHEMBL179166 | Sodium orthovanadate (SOV) | Vanada...)copy SMILEScopy InChI
Affinity DataIC50: 1.16E+4nMAssay Description:Inhibition of SHP2 (unknown origin) assessed as hydrolysis of pNPP to pNP after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2CTVPubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Qilu University of Technology

Curated by ChEMBL
LigandPNGBDBM50133030(CHEMBL3634681)copy SMILEScopy InChI
Affinity DataIC50: 1.16E+4nMAssay Description:Inhibition of SHP2 (unknown origin) assessed as hydrolysis of pNPP to pNP after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2CTVPubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Qilu University of Technology

Curated by ChEMBL
LigandPNGBDBM50391109(CHEMBL179166 | Sodium orthovanadate (SOV) | Vanada...)copy SMILEScopy InChI
Affinity DataIC50: 1.42E+4nMAssay Description:Inhibition of SHP1 (unknown origin) assessed as hydrolysis of pNPP to pNP after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2CTVPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Qilu University of Technology

Curated by ChEMBL
LigandPNGBDBM50132983(CHEMBL3634590)copy SMILEScopy InChI
Affinity DataIC50: 1.61E+4nMAssay Description:Inhibition of recombinant PTP1B (unknown origin) assessed as hydrolysis of pNPP to pNP after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2CTVPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Qilu University of Technology

Curated by ChEMBL
LigandPNGBDBM50133029(CHEMBL3634679)copy SMILEScopy InChI
Affinity DataIC50: 2.03E+4nMAssay Description:Inhibition of recombinant PTP1B (unknown origin) assessed as hydrolysis of pNPP to pNP after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2CTVPubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Qilu University of Technology

Curated by ChEMBL
LigandPNGBDBM50391109(CHEMBL179166 | Sodium orthovanadate (SOV) | Vanada...)copy SMILEScopy InChI
Affinity DataIC50: 2.23E+4nMAssay Description:Inhibition of LAR (unknown origin) assessed as hydrolysis of pNPP to pNP after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2CTVPubMed
* indicates data uncertainty>20%