Compile Data Set for Download or QSAR

Found 30 hits of Enzyme Inhibition Constant Data   

TargetD(1A) dopamine receptor(RAT)
Schering-Plough Corporation

Curated by ChEMBL
LigandPNGBDBM82247(8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-b...)copy SMILEScopy InChI
Affinity DataKi:  0.400nMAssay Description:In vitro affinity of compound towards dopamine (D1) receptor was determined by measuring their ability to displace [3H]-SCH-23,390 from rat striatal ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ31P4PubMed
TargetD(1A) dopamine receptor(RAT)
Schering-Plough Corporation

Curated by ChEMBL
LigandPNGBDBM50004823((6aS,13bR)-11-Chloro-7-methyl-5,6a,7,8,9,13b-hexah...)copy SMILEScopy InChI
Affinity DataKi:  1.90nMAssay Description:Inhibition of [3H]-SCH-23,390 binding to rat striatal homogenate dopamine receptor D1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ31P4PubMed
TargetD(1A) dopamine receptor(RAT)
Schering-Plough Corporation

Curated by ChEMBL
LigandPNGBDBM50017815(11-Chloro-7-methyl-5,6a,7,8,9,13b-hexahydro-6H-7-a...)copy SMILEScopy InChI
Affinity DataKi:  3.30nMAssay Description:Inhibition of [3H]-SCH-23,390 binding to rat striatal homogenate dopamine receptor D1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ31P4PubMed
TargetD(1A) dopamine receptor(RAT)
Schering-Plough Corporation

Curated by ChEMBL
LigandPNGBDBM50017818(7,11-Dimethyl-5,6a,7,8,9,13b-hexahydro-6H-7-aza-be...)copy SMILEScopy InChI
Affinity DataKi:  7.10nMAssay Description:Inhibition of [3H]-SCH-23,390 binding to rat striatal homogenate dopamine receptor D1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ31P4PubMed
TargetD(1A) dopamine receptor(RAT)
Schering-Plough Corporation

Curated by ChEMBL
LigandPNGBDBM50017821(12-Methoxy-7-methyl-5,6a,7,8,9,13b-hexahydro-6H-7-...)copy SMILEScopy InChI
Affinity DataKi:  24nMAssay Description:Inhibition of [3H]-SCH-23,390 binding to rat striatal homogenate dopamine receptor D1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ31P4PubMed
TargetD(1A) dopamine receptor(RAT)
Schering-Plough Corporation

Curated by ChEMBL
LigandPNGBDBM50017816(7-Methyl-5,6a,7,8,9,13b-hexahydro-6H-7-aza-benzo[6...)copy SMILEScopy InChI
Affinity DataKi:  68nMAssay Description:In vitro affinity of compound towards dopamine (D1) receptor was determined by measuring their ability to displace [3H]-SCH-23,390 from rat striatal ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ31P4PubMed
TargetD(1A) dopamine receptor(RAT)
Schering-Plough Corporation

Curated by ChEMBL
LigandPNGBDBM50017820(7-Methyl-5,6a,7,8,9,13b-hexahydro-6H-7-aza-benzo[6...)copy SMILEScopy InChI
Affinity DataKi:  73nMAssay Description:Inhibition of [3H]-SCH-23,390 binding to rat striatal homogenate dopamine receptor D1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ31P4PubMed
TargetD(1A) dopamine receptor(RAT)
Schering-Plough Corporation

Curated by ChEMBL
LigandPNGBDBM50010711((6aR,13bS )11-Chloro-7-methyl-5,6a,7,8,9,13b-hexah...)copy SMILEScopy InChI
Affinity DataKi:  474nMAssay Description:Inhibition of [3H]-SCH-23,390 binding to rat striatal homogenate dopamine receptor D1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ31P4PubMed
TargetD(1A) dopamine receptor(RAT)
Schering-Plough Corporation

Curated by ChEMBL
LigandPNGBDBM50010711((6aR,13bS )11-Chloro-7-methyl-5,6a,7,8,9,13b-hexah...)copy SMILEScopy InChI
Affinity DataKi:  513nMAssay Description:Displacement of [3H]-spiperone from rat striatal homogenate dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ31P4PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Schering-Plough Corporation

Curated by ChEMBL
LigandPNGBDBM50004823((6aS,13bR)-11-Chloro-7-methyl-5,6a,7,8,9,13b-hexah...)copy SMILEScopy InChI
Affinity DataKi:  514nMAssay Description:Displacement of [3H]-spiperone from rat striatal homogenate dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ31P4PubMed
TargetD(1A) dopamine receptor(RAT)
Schering-Plough Corporation

Curated by ChEMBL
LigandPNGBDBM50010715((6aS,13bS)11-Chloro-7-methyl-5,6a,7,8,9,13b-hexahy...)copy SMILEScopy InChI
Affinity DataKi:  531nMAssay Description:Inhibition of [3H]-SCH-23,390 binding to rat striatal homogenate dopamine receptor D1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ31P4PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Schering-Plough Corporation

Curated by ChEMBL
LigandPNGBDBM82247(8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-b...)copy SMILEScopy InChI
Affinity DataKi:  648nMAssay Description:In vitro affinity of compound towards Dopamine receptor D2 was determined by measuring their ability to displace [3H]-spiperone from rat striatal hom...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ31P4PubMed
TargetD(1A) dopamine receptor(RAT)
Schering-Plough Corporation

Curated by ChEMBL
LigandPNGBDBM50010712((6aR,13bR)11-Chloro-7-methyl-5,6a,7,8,9,13b-hexahy...)copy SMILEScopy InChI
Affinity DataKi:  898nMAssay Description:Inhibition of [3H]-SCH-23,390 binding to rat striatal homogenate dopamine receptor D1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ31P4PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Schering-Plough Corporation

Curated by ChEMBL
LigandPNGBDBM50017818(7,11-Dimethyl-5,6a,7,8,9,13b-hexahydro-6H-7-aza-be...)copy SMILEScopy InChI
Affinity DataKi:  1.51E+3nMAssay Description:Displacement of [3H]-spiperone from rat striatal homogenate dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ31P4PubMed
TargetD(1A) dopamine receptor(RAT)
Schering-Plough Corporation

Curated by ChEMBL
LigandPNGBDBM50017817(12-Methoxy-7-methyl-5,6a,7,8,9,13b-hexahydro-6H-7-...)copy SMILEScopy InChI
Affinity DataKi:  1.66E+3nMAssay Description:Inhibition of [3H]-SCH-23,390 binding to rat striatal homogenate dopamine receptor D1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ31P4PubMed
TargetD(1A) dopamine receptor(RAT)
Schering-Plough Corporation

Curated by ChEMBL
LigandPNGBDBM50017819(7-Methyl-5,6a,7,8,9,13b-hexahydro-6H-7-aza-benzo[6...)copy SMILEScopy InChI
Affinity DataKi:  1.73E+3nMAssay Description:In vitro affinity of compound towards dopamine (D1) receptor was determined by measuring their ability to displace [3H]-SCH-23,390 from rat striatal ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ31P4PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Schering-Plough Corporation

Curated by ChEMBL
LigandPNGBDBM50017816(7-Methyl-5,6a,7,8,9,13b-hexahydro-6H-7-aza-benzo[6...)copy SMILEScopy InChI
Affinity DataKi:  2.41E+3nMAssay Description:In vitro affinity of compound towards Dopamine receptor D2 was determined by measuring their ability to displace [3H]-spiperone from rat striatal hom...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ31P4PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Schering-Plough Corporation

Curated by ChEMBL
LigandPNGBDBM50017821(12-Methoxy-7-methyl-5,6a,7,8,9,13b-hexahydro-6H-7-...)copy SMILEScopy InChI
Affinity DataKi:  2.48E+3nMAssay Description:Displacement of [3H]-spiperone from rat striatal homogenate dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ31P4PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Schering-Plough Corporation

Curated by ChEMBL
LigandPNGBDBM50010715((6aS,13bS)11-Chloro-7-methyl-5,6a,7,8,9,13b-hexahy...)copy SMILEScopy InChI
Affinity DataKi:  3.05E+3nMAssay Description:Displacement of [3H]-spiperone from rat striatal homogenate dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ31P4PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Schering-Plough Corporation

Curated by ChEMBL
LigandPNGBDBM50017815(11-Chloro-7-methyl-5,6a,7,8,9,13b-hexahydro-6H-7-a...)copy SMILEScopy InChI
Affinity DataKi:  4.12E+3nMAssay Description:Displacement of [3H]-spiperone from rat striatal homogenate dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ31P4PubMed
TargetD(1A) dopamine receptor(RAT)
Schering-Plough Corporation

Curated by ChEMBL
LigandPNGBDBM50017823(11-Methoxy-7-methyl-5,6a,7,8,9,13b-hexahydro-6H-7-...)copy SMILEScopy InChI
Affinity DataKi:  4.20E+3nMAssay Description:Inhibition of [3H]-SCH-23,390 binding to rat striatal homogenate dopamine receptor D1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ31P4PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Schering-Plough Corporation

Curated by ChEMBL
LigandPNGBDBM50017817(12-Methoxy-7-methyl-5,6a,7,8,9,13b-hexahydro-6H-7-...)copy SMILEScopy InChI
Affinity DataKi:  6.40E+3nMAssay Description:Displacement of [3H]-spiperone from rat striatal homogenate dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ31P4PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Schering-Plough Corporation

Curated by ChEMBL
LigandPNGBDBM50017820(7-Methyl-5,6a,7,8,9,13b-hexahydro-6H-7-aza-benzo[6...)copy SMILEScopy InChI
Affinity DataKi:  7.87E+3nMAssay Description:Displacement of [3H]-spiperone from rat striatal homogenate dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ31P4PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Schering-Plough Corporation

Curated by ChEMBL
LigandPNGBDBM50010711((6aR,13bS )11-Chloro-7-methyl-5,6a,7,8,9,13b-hexah...)copy SMILEScopy InChI
Affinity DataKi:  9.07E+3nMAssay Description:Displacement of [3H]-spiperone from rat striatal homogenate dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ31P4PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Schering-Plough Corporation

Curated by ChEMBL
LigandPNGBDBM50010711((6aR,13bS )11-Chloro-7-methyl-5,6a,7,8,9,13b-hexah...)copy SMILEScopy InChI
Affinity DataKi:  9.07E+3nMAssay Description:Inhibition of [3H]-SCH-23,390 binding to rat striatal homogenate dopamine receptor D1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ31P4PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Schering-Plough Corporation

Curated by ChEMBL
LigandPNGBDBM50010712((6aR,13bR)11-Chloro-7-methyl-5,6a,7,8,9,13b-hexahy...)copy SMILEScopy InChI
Affinity DataKi:  1.63E+4nMAssay Description:Displacement of [3H]-spiperone from rat striatal homogenate dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ31P4PubMed
TargetD(1A) dopamine receptor(RAT)
Schering-Plough Corporation

Curated by ChEMBL
LigandPNGBDBM50017822(12-Methoxy-7-methyl-5,6a,7,8,9,13b-hexahydro-6H-7-...)copy SMILEScopy InChI
Affinity DataKi:  2.44E+4nMAssay Description:Inhibition of [3H]-SCH-23,390 binding to rat striatal homogenate dopamine receptor D1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ31P4PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Schering-Plough Corporation

Curated by ChEMBL
LigandPNGBDBM50017823(11-Methoxy-7-methyl-5,6a,7,8,9,13b-hexahydro-6H-7-...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]-spiperone from rat striatal homogenate dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ31P4PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Schering-Plough Corporation

Curated by ChEMBL
LigandPNGBDBM50017819(7-Methyl-5,6a,7,8,9,13b-hexahydro-6H-7-aza-benzo[6...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nMAssay Description:In vitro affinity of compound towards Dopamine receptor D2 was determined by measuring their ability to displace [3H]-spiperone from rat striatal hom...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ31P4PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Schering-Plough Corporation

Curated by ChEMBL
LigandPNGBDBM50017822(12-Methoxy-7-methyl-5,6a,7,8,9,13b-hexahydro-6H-7-...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]-spiperone from rat striatal homogenate dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ31P4PubMed
* indicates data uncertainty>20%