Compile Data Set for Download or QSAR

Found 10 hits of Enzyme Inhibition Constant Data   

TargetSynapsin-1(Bos taurus)
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM23408(2-(3,4-dihydroxyphenyl)-3,5,6,7-tetrahydroxy-4H-ch...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of bovine brain synapsin-1 incubated for 1 hr by ATP-[gamma35S] binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD13MTPubMed
TargetSynapsin-1(Bos taurus)
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM50180856(CHEMBL3818384)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of bovine brain synapsin-1 incubated for 1 hr by ATP-[gamma35S] binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD13MTPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM26474(5-({4-[(2,3-dimethyl-2H-indazol-6-yl)(methyl)amino...)copy SMILEScopy InChI
Affinity DataIC50: 930nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD13MTPubMed
TargetSynapsin-1(Bos taurus)
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM7533((2R)-2-[[6-(benzylamino)-9-isopropyl-purin-2-yl]am...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of bovine brain synapsin-1 incubated for 1 hr by ATP-[gamma35S] binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD13MTPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM4814(CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...)copy SMILEScopy InChI
Affinity DataIC50: 5.87E+3nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD13MTPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD13MTPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM50445351(NAMOLINE)copy SMILEScopy InChI
Affinity DataIC50: 5.10E+4nMAssay Description:Inhibition of GST-tagged LSD1 (2 to 852 residues) (unknown origin) using H3K4me2 substrate assessed as reduction in H2O2 production by fluorescence a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD13MTPubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM26197(CHEMBL112 | N-(4-hydroxyphenyl)acetamide | Norco |...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human recombinant COX1 expressed in Sf9 cell microsomes assessed as reduction in conversion of arachidonic acid to PGE2 incubated for 5...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD13MTPubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM26193(2-Hydroxybenzoate, I | 2-hydroxybenzoic acid | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of human recombinant COX1 expressed in Sf9 cell microsomes assessed as reduction in conversion of arachidonic acid to PGE2 incubated for 5...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM28700(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic a...)copy SMILEScopy InChI
Affinity DataIC50: 9.50E+5nMAssay Description:Inhibition of human recombinant COX1 expressed in Sf9 cell microsomes assessed as reduction in conversion of arachidonic acid to PGE2 incubated for 5...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD13MTPubMed
* indicates data uncertainty>20%