Compile Data Set for Download or QSAR

Found 85 hits of Enzyme Inhibition Constant Data   

TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50184767(CHEMBL3824089 | US10294227, Code 506)copy SMILEScopy InChI
Affinity DataKi:  0.800nMAssay Description:Competitive inhibition of C-terminal His-tagged full length human SRC expressed in insect cells preincubated for 20 mins using poly[Glu,Tyr]4:1 as su...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85B2DPubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50184767(CHEMBL3824089 | US10294227, Code 506)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human YES using poly[Glu,Tyr]4:1 as substrate in presence of [gamma-33P] ATPMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human ABL using EAIYAAPFAKKK as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50184776(CHEMBL3824233 | US10294227, Code 518)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of C-terminal His-tagged full length human SRC expressed in insect cells preincubated for 20 mins using poly[Glu,Tyr]4:1 as substrate meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85B2DPubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human YES using poly[Glu,Tyr]4:1 as substrate in presence of [gamma-33P] ATPMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human FYN using poly[Glu,Tyr]4:1 as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85B2DPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50184767(CHEMBL3824089 | US10294227, Code 506)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of C-terminal His-tagged full length human SRC expressed in insect cells preincubated for 20 mins using poly[Glu,Tyr]4:1 as substrate meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85B2DPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of C-terminal His-tagged full length human SRC expressed in insect cells preincubated for 20 mins using poly[Glu,Tyr]4:1 as substrate meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85B2DPubMedDrugBank
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50184777(CHEMBL3823104 | US10294227, Code 519)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of C-terminal His-tagged full length human SRC expressed in insect cells preincubated for 20 mins using poly[Glu,Tyr]4:1 as substrate meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85B2DPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50184785(CHEMBL3823620 | US10294227, Code 553)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of C-terminal His-tagged full length human SRC expressed in insect cells preincubated for 20 mins using poly[Glu,Tyr]4:1 as substrate meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85B2DPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50184786(CHEMBL3824116 | US10294227, Code 565)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of C-terminal His-tagged full length human SRC expressed in insect cells preincubated for 20 mins using poly[Glu,Tyr]4:1 as substrate meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85B2DPubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50184767(CHEMBL3824089 | US10294227, Code 506)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human FYN using poly[Glu,Tyr]4:1 as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85B2DPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50184781(CHEMBL3823543 | US10294227, Code 533)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:Inhibition of C-terminal His-tagged full length human SRC expressed in insect cells preincubated for 20 mins using poly[Glu,Tyr]4:1 as substrate meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85B2DPubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)copy SMILEScopy InChI
Affinity DataIC50: 9.90nMAssay Description:Inhibition of human PDGFRalpha using poly[Glu,Tyr]4:1 as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85B2DPubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM25116(1-tert-butyl-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of human RET using poly[Glu,Tyr]4:1 as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50184766(CHEMBL3823861 | US10294227, Code 221)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of human YES using poly[Glu,Tyr]4:1 as substrate in presence of [gamma-33P] ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85B2DPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM25116(1-tert-butyl-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of C-terminal His-tagged full length human SRC expressed in insect cells preincubated for 20 mins using poly[Glu,Tyr]4:1 as substrate meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85B2DPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50184775(CHEMBL3823451)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of C-terminal His-tagged full length human SRC expressed in insect cells preincubated for 20 mins using poly[Glu,Tyr]4:1 as substrate meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85B2DPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50184766(CHEMBL3823861 | US10294227, Code 221)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of C-terminal His-tagged full length human SRC expressed in insect cells preincubated for 20 mins using poly[Glu,Tyr]4:1 as substrate meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85B2DPubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM25116(1-tert-butyl-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of human FYN using poly[Glu,Tyr]4:1 as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85B2DPubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM25116(1-tert-butyl-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of human YES using poly[Glu,Tyr]4:1 as substrate in presence of [gamma-33P] ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85B2DPubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50184766(CHEMBL3823861 | US10294227, Code 221)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of human FYN using poly[Glu,Tyr]4:1 as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85B2DPubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Inhibition of human KIT using poly[Glu,Tyr]4:1 as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85B2DPubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50184769(CHEMBL3823212 | US10294227, Code 109)copy SMILEScopy InChI
Affinity DataIC50: 71nMAssay Description:Inhibition of human YES using poly[Glu,Tyr]4:1 as substrate in presence of [gamma-33P] ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85B2DPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50184782(CHEMBL3824228 | US10294227, Code 543)copy SMILEScopy InChI
Affinity DataIC50: 71nMAssay Description:Inhibition of C-terminal His-tagged full length human SRC expressed in insect cells preincubated for 20 mins using poly[Glu,Tyr]4:1 as substrate meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85B2DPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50184780(CHEMBL3823255 | US10294227, Code 526)copy SMILEScopy InChI
Affinity DataIC50: 114nMAssay Description:Inhibition of C-terminal His-tagged full length human SRC expressed in insect cells preincubated for 20 mins using poly[Glu,Tyr]4:1 as substrate meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85B2DPubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50184766(CHEMBL3823861 | US10294227, Code 221)copy SMILEScopy InChI
Affinity DataIC50: 116nMAssay Description:Inhibition of human ABL using EAIYAAPFAKKK as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85B2DPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50184769(CHEMBL3823212 | US10294227, Code 109)copy SMILEScopy InChI
Affinity DataIC50: 126nMAssay Description:Inhibition of C-terminal His-tagged full length human SRC expressed in insect cells preincubated for 20 mins using poly[Glu,Tyr]4:1 as substrate meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85B2DPubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM25116(1-tert-butyl-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]...)copy SMILEScopy InChI
Affinity DataIC50: 147nMAssay Description:Inhibition of human ABL using EAIYAAPFAKKK as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85B2DPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50184778(CHEMBL3823711 | US10294227, Code 540)copy SMILEScopy InChI
Affinity DataIC50: 194nMAssay Description:Inhibition of C-terminal His-tagged full length human SRC expressed in insect cells preincubated for 20 mins using poly[Glu,Tyr]4:1 as substrate meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85B2DPubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50184766(CHEMBL3823861 | US10294227, Code 221)copy SMILEScopy InChI
Affinity DataIC50: 289nMAssay Description:Inhibition of human RET using poly[Glu,Tyr]4:1 as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85B2DPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50184770(CHEMBL3823849 | US10294227, Code 112)copy SMILEScopy InChI
Affinity DataIC50: 303nMAssay Description:Inhibition of C-terminal His-tagged full length human SRC expressed in insect cells preincubated for 20 mins using poly[Glu,Tyr]4:1 as substrate meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85B2DPubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50184769(CHEMBL3823212 | US10294227, Code 109)copy SMILEScopy InChI
Affinity DataIC50: 311nMAssay Description:Inhibition of human FYN using poly[Glu,Tyr]4:1 as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85B2DPubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50184774(CHEMBL3799221)copy SMILEScopy InChI
Affinity DataIC50: 328nMAssay Description:Inhibition of human mTOR using poly[Glu,Tyr]4:1 as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85B2DPubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50184770(CHEMBL3823849 | US10294227, Code 112)copy SMILEScopy InChI
Affinity DataIC50: 344nMAssay Description:Inhibition of human YES using poly[Glu,Tyr]4:1 as substrate in presence of [gamma-33P] ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85B2DPubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50184786(CHEMBL3824116 | US10294227, Code 565)copy SMILEScopy InChI
Affinity DataIC50: 370nMAssay Description:Inhibition of human ABL using EAIYAAPFAKKK as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85B2DPubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50184776(CHEMBL3824233 | US10294227, Code 518)copy SMILEScopy InChI
Affinity DataIC50: 407nMAssay Description:Inhibition of human ABL using EAIYAAPFAKKK as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85B2DPubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)copy SMILEScopy InChI
Affinity DataIC50: 433nMAssay Description:Inhibition of human RET using poly[Glu,Tyr]4:1 as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85B2DPubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50184767(CHEMBL3824089 | US10294227, Code 506)copy SMILEScopy InChI
Affinity DataIC50: 479nMAssay Description:Inhibition of human ABL using EAIYAAPFAKKK as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85B2DPubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50184774(CHEMBL3799221)copy SMILEScopy InChI
Affinity DataIC50: 566nMAssay Description:Inhibition of human YES using poly[Glu,Tyr]4:1 as substrate in presence of [gamma-33P] ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85B2DPubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50184774(CHEMBL3799221)copy SMILEScopy InChI
Affinity DataIC50: 598nMAssay Description:Inhibition of human RET using poly[Glu,Tyr]4:1 as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85B2DPubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM25116(1-tert-butyl-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]...)copy SMILEScopy InChI
Affinity DataIC50: 657nMAssay Description:Inhibition of human PDGFRalpha using poly[Glu,Tyr]4:1 as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85B2DPubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50184772(CHEMBL3822591 | US10294227, Code 113)copy SMILEScopy InChI
Affinity DataIC50: 696nMAssay Description:Inhibition of human YES using poly[Glu,Tyr]4:1 as substrate in presence of [gamma-33P] ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85B2DPubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50184777(CHEMBL3823104 | US10294227, Code 519)copy SMILEScopy InChI
Affinity DataIC50: 808nMAssay Description:Inhibition of human ABL using EAIYAAPFAKKK as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85B2DPubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50184770(CHEMBL3823849 | US10294227, Code 112)copy SMILEScopy InChI
Affinity DataIC50: 913nMAssay Description:Inhibition of human FYN using poly[Glu,Tyr]4:1 as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85B2DPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50184772(CHEMBL3822591 | US10294227, Code 113)copy SMILEScopy InChI
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of C-terminal His-tagged full length human SRC expressed in insect cells preincubated for 20 mins using poly[Glu,Tyr]4:1 as substrate meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85B2DPubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50184774(CHEMBL3799221)copy SMILEScopy InChI
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of human ABL using EAIYAAPFAKKK as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85B2DPubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50184774(CHEMBL3799221)copy SMILEScopy InChI
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibition of human FYN using poly[Glu,Tyr]4:1 as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85B2DPubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM25116(1-tert-butyl-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]...)copy SMILEScopy InChI
Affinity DataIC50: 1.32E+3nMAssay Description:Inhibition of human KIT using poly[Glu,Tyr]4:1 as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85B2DPubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50184772(CHEMBL3822591 | US10294227, Code 113)copy SMILEScopy InChI
Affinity DataIC50: 1.96E+3nMAssay Description:Inhibition of human FYN using poly[Glu,Tyr]4:1 as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85B2DPubMed
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