Compile Data Set for Download or QSAR

Found 186 hits of Enzyme Inhibition Constant Data   

TargetHistone deacetylase 1(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188891(CHEMBL3828518)copy SMILEScopy InChI
Affinity DataIC50: 0.450nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188898(CHEMBL3828636)copy SMILEScopy InChI
Affinity DataIC50: 0.490nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188899(CHEMBL3827517)copy SMILEScopy InChI
Affinity DataIC50: 0.550nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188892(CHEMBL3828492)copy SMILEScopy InChI
Affinity DataIC50: 0.550nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188637(CHEMBL3827814)copy SMILEScopy InChI
Affinity DataIC50: 0.650nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188636(CHEMBL3827296)copy SMILEScopy InChI
Affinity DataIC50: 0.810nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM29589(Faridak | LBH-589 | LBH-589B | Panobinostat | US10...)copy SMILEScopy InChI
Affinity DataIC50: 0.830nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract using Ac-Leu-Gly-Lys (Ac)-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188726(CHEMBL3827865)copy SMILEScopy InChI
Affinity DataIC50: 0.850nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188899(CHEMBL3827517)copy SMILEScopy InChI
Affinity DataIC50: 0.860nMAssay Description:Inhibition of human recombinant HDAC10 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC as substrate assessed as release of AM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188729(CHEMBL3828180)copy SMILEScopy InChI
Affinity DataIC50: 0.970nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188900(CHEMBL3827738)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188897(CHEMBL3827281)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188959(CHEMBL3827894)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188758(CHEMBL3828408)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188890(CHEMBL3827794)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188725(CHEMBL3827650)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188894(CHEMBL3827004)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188895(CHEMBL3827660)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50189006(CHEMBL3826997)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188893(CHEMBL3828747)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188959(CHEMBL3827894)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of full length recombinant human His-tagged p110 alpha/p85 alpha expressed in baculovirus expression system incubated for 1 hr by kinase-g...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM29589(Faridak | LBH-589 | LBH-589B | Panobinostat | US10...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188903(CHEMBL3827612)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188889(CHEMBL3828289)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188909(CHEMBL3827317)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188896(CHEMBL3828628)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188961(CHEMBL3622533)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human recombinant HDAC1 (482 residues) by Color-de-Lys assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188961(CHEMBL3622533)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of full length C-terminal His-tagged human recombinant HDAC3/NCOR2 (395 to 489 residues) expressed in baculovirus infected insect Sf9 cell...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188640(CHEMBL3827780)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM29589(Faridak | LBH-589 | LBH-589B | Panobinostat | US10...)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Inhibition of full length C-terminal His-tagged human recombinant HDAC3/NCOR2 (395 to 489 residues) expressed in baculovirus infected insect Sf9 cell...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188891(CHEMBL3828518)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Inhibition of full length C-terminal His-tagged human recombinant HDAC3/NCOR2 (395 to 489 residues) expressed in baculovirus infected insect Sf9 cell...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188959(CHEMBL3827894)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Inhibition of full length human recombinant HDAC2 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC as substrate assessed as re...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188906(CHEMBL3828482)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188899(CHEMBL3827517)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Inhibition of full length C-terminal His-tagged human recombinant HDAC3/NCOR2 (395 to 489 residues) expressed in baculovirus infected insect Sf9 cell...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188899(CHEMBL3827517)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Inhibition of full length human recombinant HDAC6 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC as substrate assessed as re...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188637(CHEMBL3827814)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human recombinant HDAC10 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC as substrate assessed as release of AM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188961(CHEMBL3622533)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human recombinant HDAC10 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC as substrate assessed as release of AM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188899(CHEMBL3827517)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Inhibition of full length human recombinant HDAC2 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC as substrate assessed as re...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188959(CHEMBL3827894)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human recombinant HDAC10 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC as substrate assessed as release of AM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188637(CHEMBL3827814)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Inhibition of full length human recombinant HDAC2 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC as substrate assessed as re...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188637(CHEMBL3827814)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract using Ac-Leu-Gly-Lys (Ac)-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188959(CHEMBL3827894)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract using Ac-Leu-Gly-Lys (Ac)-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM29589(Faridak | LBH-589 | LBH-589B | Panobinostat | US10...)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Inhibition of full length human recombinant HDAC2 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC as substrate assessed as re...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188959(CHEMBL3827894)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Inhibition of full length C-terminal His-tagged human recombinant HDAC3/NCOR2 (395 to 489 residues) expressed in baculovirus infected insect Sf9 cell...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188891(CHEMBL3828518)copy SMILEScopy InChI
Affinity DataIC50: 3.40nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract using Ac-Leu-Gly-Lys (Ac)-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188637(CHEMBL3827814)copy SMILEScopy InChI
Affinity DataIC50: 3.40nMAssay Description:Inhibition of full length C-terminal His-tagged human recombinant HDAC3/NCOR2 (395 to 489 residues) expressed in baculovirus infected insect Sf9 cell...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188891(CHEMBL3828518)copy SMILEScopy InChI
Affinity DataIC50: 3.90nMAssay Description:Inhibition of full length human recombinant HDAC2 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC as substrate assessed as re...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM29589(Faridak | LBH-589 | LBH-589B | Panobinostat | US10...)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Inhibition of full length human recombinant HDAC6 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC as substrate assessed as re...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM29589(Faridak | LBH-589 | LBH-589B | Panobinostat | US10...)copy SMILEScopy InChI
Affinity DataIC50: 4.5nMAssay Description:Inhibition of human recombinant HDAC10 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC as substrate assessed as release of AM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188897(CHEMBL3827281)copy SMILEScopy InChI
Affinity DataIC50: 4.70nMAssay Description:Inhibition of full length C-terminal His-tagged human recombinant HDAC3/NCOR2 (395 to 489 residues) expressed in baculovirus infected insect Sf9 cell...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
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