Compile Data Set for Download or QSAR

Found 7 hits of Enzyme Inhibition Constant Data   

TargetFolylpolyglutamate synthase, mitochondrial(Homo sapiens (Human))
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50018235(5-Amino-2-{4-[(2,4-diamino-5-chloro-quinazolin-6-y...)copy SMILEScopy InChI
Affinity DataKi:  1.70nMAssay Description:The apparent Km of compound as a substrate for partially purified mouse liver Folyl-polyglutamate synthaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22806MJPubMed
TargetFolylpolyglutamate synthase, mitochondrial(Homo sapiens (Human))
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50002472(5-Amino-2-{4-[(2-amino-5-chloro-4-oxo-3,4-dihydro-...)copy SMILEScopy InChI
Affinity DataKi:  8.30nMAssay Description:The apparent Km of compound as a substrate for partially purified mouse liver Folyl-polyglutamate synthaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22806MJPubMed
TargetFolylpolyglutamate synthase, mitochondrial(Homo sapiens (Human))
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50018236(5-Amino-2-[4-(4-oxo-3,4-dihydro-quinazolin-6-ylmet...)copy SMILEScopy InChI
Affinity DataKi:  420nMAssay Description:The apparent Km of compound as a substrate for partially purified mouse liver Folyl-polyglutamate synthaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22806MJPubMed
TargetFolylpolyglutamate synthase, mitochondrial(Homo sapiens (Human))
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50018232(5-Amino-2-[4-(4-oxo-3,4-dihydro-quinazolin-6-ylmet...)copy SMILEScopy InChI
Affinity DataKi:  1.20E+3nMAssay Description:The apparent Km of compound as a substrate for partially purified mouse liver Folyl-polyglutamate synthaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22806MJPubMed
TargetFolylpolyglutamate synthase, mitochondrial(Homo sapiens (Human))
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50018234(5-Amino-2-[4-(2-amino-4-oxo-3,4-dihydro-quinazolin...)copy SMILEScopy InChI
Affinity DataKi:  2.80E+3nMAssay Description:The apparent Km of compound as a substrate for partially purified mouse liver Folyl-polyglutamate synthaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22806MJPubMed
TargetFolylpolyglutamate synthase, mitochondrial(Homo sapiens (Human))
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50018233(5-Amino-2-[4-(2-amino-4-oxo-3,4-dihydro-quinazolin...)copy SMILEScopy InChI
Affinity DataKi:  5.90E+3nMAssay Description:The apparent Km of compound as a substrate for partially purified mouse liver Folyl-polyglutamate synthaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22806MJPubMed
TargetFolylpolyglutamate synthase, mitochondrial(Homo sapiens (Human))
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50002473(5-Amino-2-{4-[(2-amino-4-oxo-3,4-dihydro-pteridin-...)copy SMILEScopy InChI
Affinity DataKi:  5.90E+3nMAssay Description:Binding affinity of the compound for hog liver Folyl-polyglutamate synthase was evaluatedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22806MJPubMed
* indicates data uncertainty>20%