Compile Data Set for Download or QSAR

Found 11 hits of Enzyme Inhibition Constant Data   

TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Hunan University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50188961(CHEMBL3622533)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Inhibition of HDAC10 (unknown origin) using Color de lys as substrate by HTS assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79DX7PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Hunan University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50188961(CHEMBL3622533)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of HDAC2 (unknown origin) using Color de lys as substrate by HTS assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79DX7PubMed
LigandPNGBDBM25028(4-[2-(1H-indazol-4-yl)-6-[(4-methanesulfonylpipera...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged PI3K p110alpha/untagged p85alpha expressed in baculovirus infected insect Sf9 cells...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79DX7PubMed
LigandPNGBDBM50188961(CHEMBL3622533)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged PI3K p110alpha/untagged p85alpha expressed in baculovirus infected insect Sf9 cells...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79DX7PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Hunan University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50188961(CHEMBL3622533)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of HDAC6 (unknown origin) using Color de lys as substrate by HTS assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79DX7PubMed
LigandPNGBDBM25028(4-[2-(1H-indazol-4-yl)-6-[(4-methanesulfonylpipera...)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged PI3K p110delta/untagged p85alpha expressed in baculovirus infected insect Sf9 cells...More data for this Ligand-Target Pair
LigandPNGBDBM50188961(CHEMBL3622533)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged PI3K p110delta/untagged p85alpha expressed in baculovirus infected insect Sf9 cells...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79DX7PubMed
LigandPNGBDBM25028(4-[2-(1H-indazol-4-yl)-6-[(4-methanesulfonylpipera...)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged PI3K p110beta/untagged p85alpha expressed in baculovirus infected insect Sf9 cells ...More data for this Ligand-Target Pair
LigandPNGBDBM50188961(CHEMBL3622533)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged PI3K p110beta/untagged p85alpha expressed in baculovirus infected insect Sf9 cells ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79DX7PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hunan University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50282192(CHEMBL4163321)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:Inhibition of human A431 cells derived EGFR by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79DX7PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Hunan University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50282192(CHEMBL4163321)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of Src kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79DX7PubMed
* indicates data uncertainty>20%