Compile Data Set for Download or QSAR

Found 121 hits of Enzyme Inhibition Constant Data   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452781(CHEMBL4203724)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Inverse agonist activity at Gal4-tagged human RORgammat ligand binding domain expressed in human Jurkat cells by native IL17 promoter driven lucifera...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862K0ZPubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452785(CHEMBL4213493)copy SMILEScopy InChI
Affinity DataEC50:  970nMAssay Description:Agonist activity at GAL4-tagged human LXRalpha assessed as receptor activation expressed in African green monkey CV1 cells by luciferase reporter gen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862K0ZPubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452790(CHEMBL4209091)copy SMILEScopy InChI
Affinity DataEC50:  342nMAssay Description:Agonist activity at GAL4-tagged human LXRalpha assessed as receptor activation expressed in African green monkey CV1 cells by luciferase reporter gen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862K0ZPubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452785(CHEMBL4213493)copy SMILEScopy InChI
Affinity DataEC50:  2.82E+3nMAssay Description:Agonist activity at GAL4-tagged human LXRbeta assessed as receptor activation expressed in African green monkey CV1 cells by luciferase reporter gene...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862K0ZPubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452800(CHEMBL4210530)copy SMILEScopy InChI
Affinity DataEC50:  530nMAssay Description:Inverse agonist activity at Gal4-tagged human RORgammat ligand binding domain expressed in human Jurkat cells by native IL17 promoter driven lucifera...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862K0ZPubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452801(CHEMBL4210034)copy SMILEScopy InChI
Affinity DataEC50:  165nMAssay Description:Inverse agonist activity at Gal4-tagged human RORgammat ligand binding domain expressed in human Jurkat cells by native IL17 promoter driven lucifera...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862K0ZPubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452802(CHEMBL4211266)copy SMILEScopy InChI
Affinity DataEC50:  2.04E+3nMAssay Description:Inverse agonist activity at Gal4-tagged human RORgammat ligand binding domain expressed in human Jurkat cells by native IL17 promoter driven lucifera...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862K0ZPubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452795(CHEMBL4208087)copy SMILEScopy InChI
Affinity DataEC50:  600nMAssay Description:Inverse agonist activity at Gal4-tagged human RORgammat ligand binding domain expressed in human Jurkat cells by native IL17 promoter driven lucifera...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862K0ZPubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM327745((�) 2-(4-((4-fluorophenyl)sulfonyl)-7-(1,1,...)copy SMILEScopy InChI
Affinity DataEC50:  1.51E+3nMAssay Description:Transactivation of PXR in human HepG2 cells by receptor transactivation assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862K0ZPubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM327745((�) 2-(4-((4-fluorophenyl)sulfonyl)-7-(1,1,...)copy SMILEScopy InChI
Affinity DataEC50:  1.51E+3nMAssay Description:Transactivation of PXR in human HepG2 cells by receptor transactivation assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862K0ZPubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452789(CHEMBL4214020)copy SMILEScopy InChI
Affinity DataEC50:  225nMAssay Description:Inverse agonist activity at Gal4-tagged human RORgammat ligand binding domain expressed in human Jurkat cells by native IL17 promoter driven lucifera...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862K0ZPubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452783(CHEMBL4212458)copy SMILEScopy InChI
Affinity DataEC50:  280nMAssay Description:Inverse agonist activity at Gal4-tagged human RORgammat ligand binding domain expressed in human Jurkat cells by native IL17 promoter driven lucifera...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862K0ZPubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452808(CHEMBL4216643)copy SMILEScopy InChI
Affinity DataEC50:  2.07E+3nMAssay Description:Agonist activity at GAL4-tagged human LXRalpha assessed as receptor activation expressed in African green monkey CV1 cells by luciferase reporter gen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862K0ZPubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452811(CHEMBL4208603)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Inverse agonist activity at Gal4-tagged human RORgammat ligand binding domain expressed in human Jurkat cells by native IL17 promoter driven lucifera...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862K0ZPubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM327532((�) 2-(1-((4-fluorophenyl)sulfonyl)-6-(1,1,...)copy SMILEScopy InChI
Affinity DataEC50:  47nMAssay Description:Inverse agonist activity at Gal4-tagged human RORgammat ligand binding domain expressed in human Jurkat cells by native IL17 promoter driven lucifera...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862K0ZPubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452797(CHEMBL4213534)copy SMILEScopy InChI
Affinity DataEC50:  1.64E+3nMAssay Description:Inverse agonist activity at Gal4-tagged human RORgammat ligand binding domain expressed in human Jurkat cells by native IL17 promoter driven lucifera...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862K0ZPubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM19993(CHEMBL62136 | N-[4-(1,1,1,3,3,3-hexafluoro-2-hydro...)copy SMILEScopy InChI
Affinity DataEC50:  359nMAssay Description:Agonist activity at GAL4-tagged human LXRalpha assessed as receptor activation expressed in African green monkey CV1 cells by luciferase reporter gen...More data for this Ligand-Target Pair
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452789(CHEMBL4214020)copy SMILEScopy InChI
Affinity DataEC50:  2.40E+3nMAssay Description:Agonist activity at GAL4-tagged human LXRalpha assessed as receptor activation expressed in African green monkey CV1 cells by luciferase reporter gen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862K0ZPubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452782(CHEMBL4210791)copy SMILEScopy InChI
Affinity DataEC50:  185nMAssay Description:Agonist activity at GAL4-tagged human LXRbeta assessed as receptor activation expressed in African green monkey CV1 cells by luciferase reporter gene...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862K0ZPubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452788(CHEMBL4206412)copy SMILEScopy InChI
Affinity DataEC50:  815nMAssay Description:Inverse agonist activity at Gal4-tagged human RORgammat ligand binding domain expressed in human Jurkat cells by native IL17 promoter driven lucifera...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862K0ZPubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM19993(CHEMBL62136 | N-[4-(1,1,1,3,3,3-hexafluoro-2-hydro...)copy SMILEScopy InChI
Affinity DataEC50:  333nMAssay Description:Inverse agonist activity at Gal4-tagged human RORgammat ligand binding domain expressed in human Jurkat cells by native IL17 promoter driven lucifera...More data for this Ligand-Target Pair
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452794(CHEMBL4215334)copy SMILEScopy InChI
Affinity DataEC50:  15nMAssay Description:Inverse agonist activity at Gal4-tagged human RORgammat ligand binding domain expressed in human Jurkat cells by native IL17 promoter driven lucifera...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862K0ZPubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452785(CHEMBL4213493)copy SMILEScopy InChI
Affinity DataEC50:  190nMAssay Description:Transactivation of PXR in human HepG2 cells by receptor transactivation assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862K0ZPubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452794(CHEMBL4215334)copy SMILEScopy InChI
Affinity DataEC50:  1.83E+3nMAssay Description:Transactivation of PXR in human HepG2 cells by receptor transactivation assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862K0ZPubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452806(CHEMBL4218423)copy SMILEScopy InChI
Affinity DataEC50:  2.78E+3nMAssay Description:Inverse agonist activity at Gal4-tagged human RORgammat ligand binding domain expressed in human Jurkat cells by native IL17 promoter driven lucifera...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862K0ZPubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452805(CHEMBL4211051)copy SMILEScopy InChI
Affinity DataEC50:  300nMAssay Description:Transactivation of PXR in human HepG2 cells by receptor transactivation assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862K0ZPubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452808(CHEMBL4216643)copy SMILEScopy InChI
Affinity DataEC50:  3.12E+3nMAssay Description:Agonist activity at GAL4-tagged human LXRbeta assessed as receptor activation expressed in African green monkey CV1 cells by luciferase reporter gene...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862K0ZPubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452810(CHEMBL4207135)copy SMILEScopy InChI
Affinity DataEC50:  1.26E+3nMAssay Description:Inverse agonist activity at Gal4-tagged human RORgammat ligand binding domain expressed in human Jurkat cells by native IL17 promoter driven lucifera...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862K0ZPubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452788(CHEMBL4206412)copy SMILEScopy InChI
Affinity DataEC50:  36nMAssay Description:Transactivation of PXR in human HepG2 cells by receptor transactivation assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862K0ZPubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM327745((�) 2-(4-((4-fluorophenyl)sulfonyl)-7-(1,1,...)copy SMILEScopy InChI
Affinity DataEC50:  1.10E+3nMAssay Description:Transactivation of PXR in human HepG2 cells by receptor transactivation assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862K0ZPubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452788(CHEMBL4206412)copy SMILEScopy InChI
Affinity DataEC50:  550nMAssay Description:Agonist activity at GAL4-tagged human LXRbeta assessed as receptor activation expressed in African green monkey CV1 cells by luciferase reporter gene...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862K0ZPubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452793(CHEMBL4214210)copy SMILEScopy InChI
Affinity DataEC50: >7.50E+3nMAssay Description:Agonist activity at GAL4-tagged human LXRbeta assessed as receptor activation expressed in African green monkey CV1 cells by luciferase reporter gene...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862K0ZPubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452791(CHEMBL4205428)copy SMILEScopy InChI
Affinity DataEC50:  2.45E+3nMAssay Description:Agonist activity at GAL4-tagged human LXRbeta assessed as receptor activation expressed in African green monkey CV1 cells by luciferase reporter gene...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862K0ZPubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM327473(N—((S)-2-fluoro-3-hydroxy-3-methylbutyl)-2-((...)copy SMILEScopy InChI
Affinity DataEC50:  39nMAssay Description:Inverse agonist activity at Gal4-tagged human RORgammat ligand binding domain expressed in human Jurkat cells by native IL17 promoter driven lucifera...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862K0ZPubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452784(CHEMBL4214711)copy SMILEScopy InChI
Affinity DataEC50:  175nMAssay Description:Transactivation of PXR in human HepG2 cells by receptor transactivation assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452793(CHEMBL4214210)copy SMILEScopy InChI
Affinity DataEC50:  2.82E+3nMAssay Description:Agonist activity at GAL4-tagged human LXRalpha assessed as receptor activation expressed in African green monkey CV1 cells by luciferase reporter gen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862K0ZPubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM327745((�) 2-(4-((4-fluorophenyl)sulfonyl)-7-(1,1,...)copy SMILEScopy InChI
Affinity DataEC50:  792nMAssay Description:Agonist activity at GAL4-tagged human LXRalpha assessed as receptor activation expressed in African green monkey CV1 cells by luciferase reporter gen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862K0ZPubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452795(CHEMBL4208087)copy SMILEScopy InChI
Affinity DataEC50:  445nMAssay Description:Agonist activity at GAL4-tagged human LXRbeta assessed as receptor activation expressed in African green monkey CV1 cells by luciferase reporter gene...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862K0ZPubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452803(CHEMBL4212014)copy SMILEScopy InChI
Affinity DataEC50:  230nMAssay Description:Inverse agonist activity at Gal4-tagged human RORgammat ligand binding domain expressed in human Jurkat cells by native IL17 promoter driven lucifera...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862K0ZPubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452805(CHEMBL4211051)copy SMILEScopy InChI
Affinity DataEC50:  15nMAssay Description:Inverse agonist activity at Gal4-tagged human RORgammat ligand binding domain expressed in human Jurkat cells by native IL17 promoter driven lucifera...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862K0ZPubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452796(CHEMBL4217418)copy SMILEScopy InChI
Affinity DataEC50:  18nMAssay Description:Transactivation of PXR in human HepG2 cells by receptor transactivation assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862K0ZPubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452782(CHEMBL4210791)copy SMILEScopy InChI
Affinity DataEC50:  190nMAssay Description:Agonist activity at GAL4-tagged human LXRalpha assessed as receptor activation expressed in African green monkey CV1 cells by luciferase reporter gen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862K0ZPubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452807(CHEMBL4217890)copy SMILEScopy InChI
Affinity DataEC50:  93nMAssay Description:Inverse agonist activity at Gal4-tagged human RORgammat ligand binding domain expressed in human Jurkat cells by native IL17 promoter driven lucifera...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862K0ZPubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452809(CHEMBL4205663)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Inverse agonist activity at Gal4-tagged human RORgammat ligand binding domain expressed in human Jurkat cells by native IL17 promoter driven lucifera...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862K0ZPubMed
TargetNuclear receptor ROR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452782(CHEMBL4210791)copy SMILEScopy InChI
Affinity DataEC50: >4.00E+3nMAssay Description:Agonist activity at Gal4-tagged human RORalpha ligand binding domain expressed in human Jurkat cells by native IL17 promoter driven luciferase report...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862K0ZPubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452808(CHEMBL4216643)copy SMILEScopy InChI
Affinity DataEC50:  250nMAssay Description:Transactivation of PXR in human HepG2 cells by receptor transactivation assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862K0ZPubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452790(CHEMBL4209091)copy SMILEScopy InChI
Affinity DataEC50:  254nMAssay Description:Transactivation of PXR in human HepG2 cells by receptor transactivation assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862K0ZPubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452782(CHEMBL4210791)copy SMILEScopy InChI
Affinity DataEC50:  165nMAssay Description:Inverse agonist activity at Gal4-tagged human RORgammat ligand binding domain expressed in human Jurkat cells by native IL17 promoter driven lucifera...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862K0ZPubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452783(CHEMBL4212458)copy SMILEScopy InChI
Affinity DataEC50:  25nMAssay Description:Transactivation of PXR in human HepG2 cells by receptor transactivation assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862K0ZPubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM327745((�) 2-(4-((4-fluorophenyl)sulfonyl)-7-(1,1,...)copy SMILEScopy InChI
Affinity DataEC50:  792nMAssay Description:Agonist activity at GAL4-tagged human LXRalpha assessed as receptor activation expressed in African green monkey CV1 cells by luciferase reporter gen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862K0ZPubMed
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