Compile Data Set for Download or QSAR

Found 13 hits of Enzyme Inhibition Constant Data   

TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50292371(CHEMBL4171617)copy SMILEScopy InChI
Affinity DataIC50: 5.60nMAssay Description:Ability to inhibit HMG-CoA reductase (HMGR) by CoA reductase inhibition screen (COR) in ratsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ643KPubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50291874(CHEMBL4159805)copy SMILEScopy InChI
Affinity DataIC50: 5.60nMAssay Description:Inhibition of Chk2 (unknown origin) assessed as decrease in Cdc25C phosphorylation at Ser216 by ELISA based spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ643KPubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50287578(CHEMBL4167715)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of Chk2 (unknown origin) assessed as decrease in Cdc25C phosphorylation at Ser216 by ELISA based spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ643KPubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50291880(CHEMBL4164161)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of Chk2 (unknown origin) assessed as decrease in Cdc25C phosphorylation at Ser216 by ELISA based spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ643KPubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50291876(CHEMBL4165274)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in rat frontal cortex using [3H]8-OH-DPAT as a radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ643KPubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50291882(CHEMBL4160772)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of Chk2 (unknown origin) assessed as decrease in Cdc25C phosphorylation at Ser216 by ELISA based spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ643KPubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50291877(CHEMBL4175894)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Binding affinity against 5-HT1B receptor in rat brain membrane using [3H]8-OH-DPAT as a selective ligand.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ643KPubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50163251(2-(4-(4-hydroxyphenylthio)phenyl)-1H-benzo[d]imida...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of Chk2 (unknown origin) assessed as decrease in Cdc25C phosphorylation at Ser216 by ELISA based spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ643KPubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50291878(CHEMBL4161839)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of Chk2 (unknown origin) assessed as decrease in Cdc25C phosphorylation at Ser216 by ELISA based spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ643KPubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50291881(CHEMBL4168692)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibitory activity against purified human plasma renin at pH 6.0More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ643KPubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50291879(CHEMBL4172486)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of Chk2 (unknown origin) assessed as decrease in Cdc25C phosphorylation at Ser216 by ELISA based spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ643KPubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50292365(CHEMBL4160383)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of Chk2 (unknown origin) assessed as decrease in Cdc25C phosphorylation at Ser216 by ELISA based spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ643KPubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50292370(CHEMBL4170989)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Inhibition of Chk2 (unknown origin) assessed as decrease in Cdc25C phosphorylation at Ser216 by ELISA based spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ643KPubMed
* indicates data uncertainty>20%