Compile Data Set for Download or QSAR

Found 193 hits of Enzyme Inhibition Constant Data   

TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50172079(CHEMBL3809489)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of wild-type human partial length AXL (R497 to Y821 residues) expressed in bacterial expression system using poly [Glu, Try] 4:1 as substr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QKCPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50172079(CHEMBL3809489)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Inhibition of wild-type human partial length FLT3 (V592 to Y969 residues) expressed in bacterial expression system using poly [Glu, Try] 4:1 as subst...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QKCPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50455346(CHEMBL4218175)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of wild-type human partial length FLT3 (V592 to Y969 residues) expressed in bacterial expression system using poly [Glu, Try] 4:1 as subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QKCPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50172079(CHEMBL3809489)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human partial length FLT3 D835Y mutant (Q580 to Y969 residues) expressed in bacterial expression system using poly [Glu, Try] 4:1 as su...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QKCPubMed
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50384576(CHEMBL2036808)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Inhibition of MER (unknown origin)More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50172079(CHEMBL3809489)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of wild-type human partial length RET (E713 to D1014 residues) expressed in bacterial expression system using poly [Glu, Try] 4:1 as subst...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QKCPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50455346(CHEMBL4218175)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human partial length FLT3 D835Y mutant (Q580 to Y969 residues) expressed in bacterial expression system using poly [Glu, Try] 4:1 as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QKCPubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50455346(CHEMBL4218175)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of wild-type human partial length RET (E713 to D1014 residues) expressed in bacterial expression system using poly [Glu, Try] 4:1 as subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QKCPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50172079(CHEMBL3809489)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of human partial length FLT3 ITD mutant expressed in bacterial expression system using poly [Glu, Try] 4:1 as substrate in presence of [ga...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QKCPubMed
TargetAurora kinase A(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50455346(CHEMBL4218175)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of human partial length Aurora A (E122 to K401 residues) expressed in mammalian expression system using poly [Glu, Try] 4:1 as substrate i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QKCPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50455354(CHEMBL4208852)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of wild-type human partial length FLT3 (V592 to Y969 residues) expressed in bacterial expression system using poly [Glu, Try] 4:1 as subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QKCPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50172079(CHEMBL3809489)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of wild-type human partial length VEGFR2 (R787 to P1253 residues) expressed in mammalian expression system using poly [Glu, Try] 4:1 as su...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QKCPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50455346(CHEMBL4218175)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of human partial length FLT3 ITD mutant expressed in bacterial expression system using poly [Glu, Try] 4:1 as substrate in presence of [ga...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QKCPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50455354(CHEMBL4208852)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of human partial length FLT3 D835Y mutant (Q580 to Y969 residues) expressed in bacterial expression system using poly [Glu, Try] 4:1 as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QKCPubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50455346(CHEMBL4218175)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of wild-type human partial length AXL (R497 to Y821 residues) expressed in bacterial expression system using poly [Glu, Try] 4:1 as substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QKCPubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50384600(CHEMBL2036792 | US9744172, Compound UNC00000563A)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of AXL (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QKCPubMed
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50172079(CHEMBL3809489)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of wild-type human partial length MER (R557 to L884 residues) expressed in bacterial expression system using poly [Glu, Try] 4:1 as substr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QKCPubMed
TargetTyrosine-protein kinase receptor TYRO3(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50172079(CHEMBL3809489)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of wild-type human partial length TYRO3 (S497 to T814 residues) expressed in bacterial expression system using poly [Glu, Try] 4:1 as subs...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QKCPubMed
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50384600(CHEMBL2036792 | US9744172, Compound UNC00000563A)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of MER (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QKCPubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50172079(CHEMBL3809489)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of wild-type human partial length PDGFRA (V575 to D1002 residues) expressed in mammalian expression system using poly [Glu, Try] 4:1 as su...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QKCPubMed
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50172079(CHEMBL3809489)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of wild-type human partial length DDR1 (R565 to V876 residues) expressed in bacterial expression system using poly [Glu, Try] 4:1 as subst...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QKCPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50455348(CHEMBL4213003)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of wild-type human partial length FLT3 (V592 to Y969 residues) expressed in bacterial expression system using poly [Glu, Try] 4:1 as subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QKCPubMed
TargetAurora kinase A(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50172079(CHEMBL3809489)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of human partial length Aurora A (E122 to K401 residues) expressed in mammalian expression system using poly [Glu, Try] 4:1 as substrate i...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QKCPubMed
TargetAurora kinase A(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50455354(CHEMBL4208852)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of human partial length Aurora A (E122 to K401 residues) expressed in mammalian expression system using poly [Glu, Try] 4:1 as substrate i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QKCPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50455354(CHEMBL4208852)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of human partial length FLT3 ITD mutant expressed in bacterial expression system using poly [Glu, Try] 4:1 as substrate in presence of [ga...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QKCPubMed
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50455346(CHEMBL4218175)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of wild-type human partial length DDR1 (R565 to V876 residues) expressed in bacterial expression system using poly [Glu, Try] 4:1 as subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QKCPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50172079(CHEMBL3809489)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Inhibition of wild-type human partial length SRC (L240 to L536 residues) expressed in bacterial expression system using poly [Glu, Try] 4:1 as substr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QKCPubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50384576(CHEMBL2036808)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Inhibition of AXL (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QKCPubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50455348(CHEMBL4213003)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of wild-type human partial length RET (E713 to D1014 residues) expressed in bacterial expression system using poly [Glu, Try] 4:1 as subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QKCPubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50455346(CHEMBL4218175)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of wild-type human partial length ALK (I1088 to E1409 residues) expressed in mammalian expression system using poly [Glu, Try] 4:1 as subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QKCPubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50455354(CHEMBL4208852)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of wild-type human partial length RET (E713 to D1014 residues) expressed in bacterial expression system using poly [Glu, Try] 4:1 as subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QKCPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50455346(CHEMBL4218175)copy SMILEScopy InChI
Affinity DataIC50: 66nMAssay Description:Inhibition of wild-type human partial length VEGFR2 (R787 to P1253 residues) expressed in mammalian expression system using poly [Glu, Try] 4:1 as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QKCPubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50455346(CHEMBL4218175)copy SMILEScopy InChI
Affinity DataIC50: 68nMAssay Description:Inhibition of wild-type human partial length KIT (I571 to D952 residues) expressed in bacterial expression system using poly [Glu, Try] 4:1 as substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QKCPubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50455354(CHEMBL4208852)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of wild-type human partial length AXL (R497 to Y821 residues) expressed in bacterial expression system using poly [Glu, Try] 4:1 as substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QKCPubMed
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50455346(CHEMBL4218175)copy SMILEScopy InChI
Affinity DataIC50: 92nMAssay Description:Inhibition of wild-type human partial length MER (R557 to L884 residues) expressed in bacterial expression system using poly [Glu, Try] 4:1 as substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QKCPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50455346(CHEMBL4218175)copy SMILEScopy InChI
Affinity DataIC50: 93nMAssay Description:Inhibition of wild-type human partial length SRC (L240 to L536 residues) expressed in bacterial expression system using poly [Glu, Try] 4:1 as substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QKCPubMed
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50455354(CHEMBL4208852)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of wild-type human partial length DDR1 (R565 to V876 residues) expressed in bacterial expression system using poly [Glu, Try] 4:1 as subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QKCPubMed
TargetAurora kinase B(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50172079(CHEMBL3809489)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of wild-type human partial length AURKB (D25 to A303 residues) expressed in mammalian expression system using poly [Glu, Try] 4:1 as subst...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QKCPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50455345(CHEMBL4214476)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of wild-type human partial length FLT3 (V592 to Y969 residues) expressed in bacterial expression system using poly [Glu, Try] 4:1 as subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QKCPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50455350(CHEMBL4213775)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of wild-type human partial length FLT3 (V592 to Y969 residues) expressed in bacterial expression system using poly [Glu, Try] 4:1 as subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QKCPubMed
TargetAurora kinase B(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50455346(CHEMBL4218175)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of wild-type human partial length AURKB (D25 to A303 residues) expressed in mammalian expression system using poly [Glu, Try] 4:1 as subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QKCPubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50455348(CHEMBL4213003)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of wild-type human partial length AXL (R497 to Y821 residues) expressed in bacterial expression system using poly [Glu, Try] 4:1 as substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QKCPubMed
TargetAurora kinase A(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50455348(CHEMBL4213003)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of human partial length Aurora A (E122 to K401 residues) expressed in mammalian expression system using poly [Glu, Try] 4:1 as substrate i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QKCPubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50455345(CHEMBL4214476)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of wild-type human partial length RET (E713 to D1014 residues) expressed in bacterial expression system using poly [Glu, Try] 4:1 as subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QKCPubMed
TargetAurora kinase B(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50455354(CHEMBL4208852)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibition of wild-type human partial length AURKB (D25 to A303 residues) expressed in mammalian expression system using poly [Glu, Try] 4:1 as subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QKCPubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50455354(CHEMBL4208852)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Inhibition of wild-type human partial length ALK (I1088 to E1409 residues) expressed in mammalian expression system using poly [Glu, Try] 4:1 as subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QKCPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50455351(CHEMBL4209569)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Inhibition of wild-type human partial length FLT3 (V592 to Y969 residues) expressed in bacterial expression system using poly [Glu, Try] 4:1 as subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QKCPubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50455350(CHEMBL4213775)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Inhibition of wild-type human partial length AXL (R497 to Y821 residues) expressed in bacterial expression system using poly [Glu, Try] 4:1 as substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QKCPubMed
TargetAurora kinase A(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50455350(CHEMBL4213775)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Inhibition of human partial length Aurora A (E122 to K401 residues) expressed in mammalian expression system using poly [Glu, Try] 4:1 as substrate i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QKCPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50455352(CHEMBL4204515)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of wild-type human partial length FLT3 (V592 to Y969 residues) expressed in bacterial expression system using poly [Glu, Try] 4:1 as subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QKCPubMed
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