Compile Data Set for Download or QSAR

Found 33 hits of Enzyme Inhibition Constant Data   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM1774(US10894048, Ref. Ex Comp. 1 | US8476284, 13)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of BTK (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9SZ0PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50161162(AVL-292 | CC-292 | Spebrutinib | US10596172, Compo...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9SZ0PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50369720(CHEMBL3979355)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9SZ0PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM36516(4-(tert-Butyl)-N-(2-methyl-3-(4-methyl-6-((4-(morp...)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50369721(CHEMBL3702836)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9SZ0PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50369718(CHEMBL4172284)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9SZ0PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50369722(CHEMBL4175428)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9SZ0PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50175583(ACP-196 | Acalabrutinib | US10239883, Example 6 | ...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50369723(CHEMBL4167139)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9SZ0PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50388189(CHEMBL2057918)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
LigandPNGBDBM50369720(CHEMBL3979355)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of JAK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9SZ0PubMed
TargetTyrosine-protein kinase Tec(Homo sapiens (Human))
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50369722(CHEMBL4175428)copy SMILEScopy InChI
Affinity DataIC50: 5.30nMAssay Description:Inhibition of TEC (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9SZ0PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50369719(CHEMBL4162057)copy SMILEScopy InChI
Affinity DataIC50: 5.90nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9SZ0PubMed
TargetTyrosine-protein kinase Tec(Homo sapiens (Human))
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50161162(AVL-292 | CC-292 | Spebrutinib | US10596172, Compo...)copy SMILEScopy InChI
Affinity DataIC50: 6.20nMAssay Description:Inhibition of TEC (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9SZ0PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50388189(CHEMBL2057918)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of BTK (unknown origin) assessed as reduction in TNF productionMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50012060(CHEMBL3263640)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9SZ0PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50369720(CHEMBL3979355)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of ErbB4/HER4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9SZ0PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM1774(US10894048, Ref. Ex Comp. 1 | US8476284, 13)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of ITK (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9SZ0PubMed
TargetTyrosine-protein kinase Tec(Homo sapiens (Human))
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50012060(CHEMBL3263640)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of TEC (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9SZ0PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50160871(BI 1482694 | HM61713 | Olmutinib)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of EGFR exon 19 deletion and L858R mutant phosphorylation in human NCI-H1975 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9SZ0PubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50369718(CHEMBL4172284)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of BMX (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9SZ0PubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50012060(CHEMBL3263640)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of BMX (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9SZ0PubMed
TargetSTE20-like serine/threonine-protein kinase(Homo sapiens (Human))
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50388189(CHEMBL2057918)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Inhibition of SLK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9SZ0PubMed
TargetTyrosine-protein kinase Tec(Homo sapiens (Human))
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50369718(CHEMBL4172284)copy SMILEScopy InChI
Affinity DataIC50: 57nMAssay Description:Inhibition of TEC (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9SZ0PubMed
TargetTyrosine-protein kinase Tec(Homo sapiens (Human))
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50388189(CHEMBL2057918)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:Inhibition of TEC (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9SZ0PubMed
TargetTyrosine-protein kinase Tec(Homo sapiens (Human))
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM1774(US10894048, Ref. Ex Comp. 1 | US8476284, 13)copy SMILEScopy InChI
Affinity DataIC50: 78nMAssay Description:Inhibition of TEC (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9SZ0PubMed
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM1774(US10894048, Ref. Ex Comp. 1 | US8476284, 13)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of LYN (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9SZ0PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50369724(HM71224 | Ly3337641 | Poseltinib)copy SMILEScopy InChI
Affinity DataIC50: 652nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9SZ0PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50160871(BI 1482694 | HM61713 | Olmutinib)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of wild type EGFR phosphorylation in human H358 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9SZ0PubMed
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50161162(AVL-292 | CC-292 | Spebrutinib | US10596172, Compo...)copy SMILEScopy InChI
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of LYN (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9SZ0PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50369723(CHEMBL4167139)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9SZ0PubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM1774(US10894048, Ref. Ex Comp. 1 | US8476284, 13)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SYK (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9SZ0PubMed
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50369721(CHEMBL3702836)copy SMILEScopy InChI
Affinity DataKd:  0.540nMAssay Description:Binding affinity to RPS6KA3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9SZ0PubMed
* indicates data uncertainty>20%