Compile Data Set for Download or QSAR

Found 25 hits of Enzyme Inhibition Constant Data   

TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50467749(CHEMBL4281478)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human kidneyl SGLT2 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-AMG uptake preincubated for 10 mins followed b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB779GPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50467757(CHEMBL4294285)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human kidneyl SGLT2 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-AMG uptake preincubated for 10 mins followed b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB779GPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50467755(CHEMBL4291795)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human kidneyl SGLT2 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-AMG uptake preincubated for 10 mins followed b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB779GPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50467754(CHEMBL4286399)copy SMILEScopy InChI
Affinity DataIC50: 5.30nMAssay Description:Inhibition of human kidneyl SGLT2 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-AMG uptake preincubated for 10 mins followed b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB779GPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50467751(CHEMBL4293989)copy SMILEScopy InChI
Affinity DataIC50: 7.5nMAssay Description:Inhibition of human kidneyl SGLT2 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-AMG uptake preincubated for 10 mins followed b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB779GPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50467756(CHEMBL4289884)copy SMILEScopy InChI
Affinity DataIC50: 8.30nMAssay Description:Inhibition of human kidneyl SGLT2 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-AMG uptake preincubated for 10 mins followed b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB779GPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50467750(CHEMBL4279519)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of human kidneyl SGLT2 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-AMG uptake preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB779GPubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50467755(CHEMBL4291795)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of human small intestinal SGLT1 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-AMG uptake preincubated for 10 mins f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB779GPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50467753(CHEMBL4279564)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of human kidneyl SGLT2 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-AMG uptake preincubated for 10 mins followed b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB779GPubMed
TargetSodium/glucose cotransporter 2(Rattus norvegicus)
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50467750(CHEMBL4279519)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of rat SGLT2 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-AMG uptake preincubated for 10 mins followed by [14C]-AM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB779GPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50467759(CHEMBL4285963)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of human kidneyl SGLT2 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-AMG uptake preincubated for 10 mins followed b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB779GPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50467758(CHEMBL4285800)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of human kidneyl SGLT2 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-AMG uptake preincubated for 10 mins followed b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB779GPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50467752(CHEMBL4287888)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of human kidneyl SGLT2 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-AMG uptake preincubated for 10 mins followed b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB779GPubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50467753(CHEMBL4279564)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of human small intestinal SGLT1 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-AMG uptake preincubated for 10 mins f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB779GPubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50467750(CHEMBL4279519)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Inhibition of human small intestinal SGLT1 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-AMG uptake preincubated for 10 mins f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB779GPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50467760(CHEMBL4282708)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Inhibition of human kidneyl SGLT2 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-AMG uptake preincubated for 10 mins followed b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB779GPubMed
TargetSodium/glucose cotransporter 1(Rattus norvegicus)
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50467750(CHEMBL4279519)copy SMILEScopy InChI
Affinity DataIC50: 68nMAssay Description:Inhibition of rat SGLT1 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-AMG uptake preincubated for 10 mins followed by [14C]-AM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB779GPubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50467757(CHEMBL4294285)copy SMILEScopy InChI
Affinity DataIC50: 86nMAssay Description:Inhibition of human small intestinal SGLT1 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-AMG uptake preincubated for 10 mins f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB779GPubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50467751(CHEMBL4293989)copy SMILEScopy InChI
Affinity DataIC50: 96nMAssay Description:Inhibition of human small intestinal SGLT1 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-AMG uptake preincubated for 10 mins f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB779GPubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50467758(CHEMBL4285800)copy SMILEScopy InChI
Affinity DataIC50: 101nMAssay Description:Inhibition of human small intestinal SGLT1 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-AMG uptake preincubated for 10 mins f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB779GPubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50467752(CHEMBL4287888)copy SMILEScopy InChI
Affinity DataIC50: 156nMAssay Description:Inhibition of human small intestinal SGLT1 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-AMG uptake preincubated for 10 mins f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB779GPubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50467756(CHEMBL4289884)copy SMILEScopy InChI
Affinity DataIC50: 163nMAssay Description:Inhibition of human small intestinal SGLT1 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-AMG uptake preincubated for 10 mins f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB779GPubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50467760(CHEMBL4282708)copy SMILEScopy InChI
Affinity DataIC50: 187nMAssay Description:Inhibition of human small intestinal SGLT1 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-AMG uptake preincubated for 10 mins f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB779GPubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50467759(CHEMBL4285963)copy SMILEScopy InChI
Affinity DataIC50: 376nMAssay Description:Inhibition of human small intestinal SGLT1 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-AMG uptake preincubated for 10 mins f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB779GPubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50467754(CHEMBL4286399)copy SMILEScopy InChI
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibition of human small intestinal SGLT1 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-AMG uptake preincubated for 10 mins f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB779GPubMed
* indicates data uncertainty>20%