Compile Data Set for Download or QSAR

Found 19 hits of Enzyme Inhibition Constant Data   

TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50196528(CHEMBL3923120 | US10167270, Example 00161 | US1050...)copy SMILEScopy InChI
Affinity DataIC50: 8.30nMAssay Description:Inhibition of wild type recombinant human lysosomal beta-glucocerebrosidase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280562CPubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50196514(CHEMBL3950881 | US10167270, Example 00159)copy SMILEScopy InChI
Affinity DataIC50: 8.70nMAssay Description:Inhibition of wild type recombinant human lysosomal beta-glucocerebrosidase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280562CPubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50196622(CHEMBL3923147 | US10167270, Example 00160 | US1050...)copy SMILEScopy InChI
Affinity DataIC50: 9.90nMAssay Description:Inhibition of wild type recombinant human lysosomal beta-glucocerebrosidase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280562CPubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50196531(CHEMBL3964444 | US10167270, Compound 7a)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of wild type recombinant human lysosomal beta-glucocerebrosidase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280562CPubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50196530(CHEMBL3974789 | US10167270, Compound 7b)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibition of wild type recombinant human lysosomal beta-glucocerebrosidase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280562CPubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50033286(CHEMBL544818 | Phenethyl-(2-pyridin-3-yl-quinazoli...)copy SMILEScopy InChI
Affinity DataIC50: 97nMAssay Description:Inhibition of wild type recombinant human lysosomal beta-glucocerebrosidase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280562CPubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50196518(CHEMBL3920301 | US10167270, Compound 4)copy SMILEScopy InChI
Affinity DataIC50: 177nMAssay Description:Inhibition of wild type recombinant human lysosomal beta-glucocerebrosidase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280562CPubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM313305(US10167270, Example 84)copy SMILEScopy InChI
Affinity DataIC50: 430nMAssay Description:Inhibition of wild type recombinant human lysosomal beta-glucocerebrosidase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280562CPubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50196516(CHEMBL3968279 | US10167270, Compound 7c)copy SMILEScopy InChI
Affinity DataIC50: 720nMAssay Description:Inhibition of wild type recombinant human lysosomal beta-glucocerebrosidase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280562CPubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50196626(CHEMBL3972062 | US10167270, Compound 8e)copy SMILEScopy InChI
Affinity DataIC50: 1.28E+3nMAssay Description:Inhibition of wild type recombinant human lysosomal beta-glucocerebrosidase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280562CPubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50196630(CHEMBL3942452 | US10167270, Compound 8d)copy SMILEScopy InChI
Affinity DataIC50: 1.78E+3nMAssay Description:Inhibition of wild type recombinant human lysosomal beta-glucocerebrosidase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280562CPubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM313417(US10167270, Example 97)copy SMILEScopy InChI
Affinity DataIC50: 1.88E+3nMAssay Description:Inhibition of wild type recombinant human lysosomal beta-glucocerebrosidase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280562CPubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM313224(US10167270, Example 2)copy SMILEScopy InChI
Affinity DataIC50: 2.14E+3nMAssay Description:Inhibition of wild type recombinant human lysosomal beta-glucocerebrosidase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280562CPubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM313411(US10167270, Example 91)copy SMILEScopy InChI
Affinity DataIC50: 2.54E+3nMAssay Description:Inhibition of wild type recombinant human lysosomal beta-glucocerebrosidase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280562CPubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM313412(US10167270, Example 92)copy SMILEScopy InChI
Affinity DataIC50: 4.24E+3nMAssay Description:Inhibition of wild type recombinant human lysosomal beta-glucocerebrosidase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280562CPubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50525974(CHEMBL4444925)copy SMILEScopy InChI
Affinity DataIC50: 5.87E+3nMAssay Description:Inhibition of wild type recombinant human lysosomal beta-glucocerebrosidase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280562CPubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM313443(US10167270, Example 140)copy SMILEScopy InChI
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of wild type recombinant human lysosomal beta-glucocerebrosidase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280562CPubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50525975(CHEMBL4530904)copy SMILEScopy InChI
Affinity DataIC50: 8.38E+3nMAssay Description:Inhibition of wild type recombinant human lysosomal beta-glucocerebrosidase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280562CPubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM313430(US10167270, Example 121)copy SMILEScopy InChI
Affinity DataIC50: 9.94E+3nMAssay Description:Inhibition of wild type recombinant human lysosomal beta-glucocerebrosidase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280562CPubMed
* indicates data uncertainty>20%