Compile Data Set for Download or QSAR

Found 24 hits of Enzyme Inhibition Constant Data   

TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50532176(CHEMBL4542928)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human N-terminal FLAG/His-tagged KDM5B (2 to 751 residues) expressed in baculovirus infected Sf9 insect cells using H3(1-21)K4(Me3)-GGK...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668HPRPubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50532176(CHEMBL4542928)copy SMILEScopy InChI
Affinity DataIC50: 4.40nMAssay Description:Inhibition of human C-terminal FLAG-tagged KDM5A (1 to 1090 residues) expressed in baculovirus infected Sf9 insect cells using H3(1-21)K4(Me3)-GGK(Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668HPRPubMed
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50532173(CHEMBL4536443)copy SMILEScopy InChI
Affinity DataIC50: 5.80nMAssay Description:Inhibition of full-length human N-terminal FLAG/His-tagged KDM5C (2 to 1560 residues) expressed in baculovirus infected Sf9 insect cells using H3(1-2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668HPRPubMed
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50532176(CHEMBL4542928)copy SMILEScopy InChI
Affinity DataIC50: 6.20nMAssay Description:Inhibition of full-length human N-terminal FLAG/His-tagged KDM5C (2 to 1560 residues) expressed in baculovirus infected Sf9 insect cells using H3(1-2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668HPRPubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50532173(CHEMBL4536443)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of human C-terminal FLAG-tagged KDM5A (1 to 1090 residues) expressed in baculovirus infected Sf9 insect cells using H3(1-21)K4(Me3)-GGK(Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668HPRPubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50532173(CHEMBL4536443)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Inhibition of human N-terminal FLAG/His-tagged KDM5B (2 to 751 residues) expressed in baculovirus infected Sf9 insect cells using H3(1-21)K4(Me3)-GGK...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668HPRPubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50532175(CHEMBL4436444)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:Inhibition of human C-terminal FLAG-tagged KDM5A (1 to 1090 residues) expressed in baculovirus infected Sf9 insect cells using H3(1-21)K4(Me3)-GGK(Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668HPRPubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50532174(CHEMBL4446067)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibition of human C-terminal FLAG-tagged KDM5A (1 to 1090 residues) expressed in baculovirus infected Sf9 insect cells using H3(1-21)K4(Me3)-GGK(Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668HPRPubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50532177(CHEMBL4556977)copy SMILEScopy InChI
Affinity DataIC50: 179nMAssay Description:Inhibition of human C-terminal FLAG-tagged KDM5A (1 to 1090 residues) expressed in baculovirus infected Sf9 insect cells using H3(1-21)K4(Me3)-GGK(Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668HPRPubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM195608(CPI-455)copy SMILEScopy InChI
Affinity DataIC50: 337nMAssay Description:Inhibition of human N-terminal FLAG/His-tagged KDM5B (2 to 751 residues) expressed in baculovirus infected Sf9 insect cells using H3(1-21)K4(Me3)-GGK...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668HPRPubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM195608(CPI-455)copy SMILEScopy InChI
Affinity DataIC50: 506nMAssay Description:Inhibition of human C-terminal FLAG-tagged KDM5A (1 to 1090 residues) expressed in baculovirus infected Sf9 insect cells using H3(1-21)K4(Me3)-GGK(Bi...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50095446(CHEMBL3590426)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human C-terminal FLAG-tagged KDM5A (1 to 1090 residues) expressed in baculovirus infected Sf9 insect cells using H3(1-21)K4(Me3)-GGK(Bi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668HPRPubMed
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM195608(CPI-455)copy SMILEScopy InChI
Affinity DataIC50: 3.01E+3nMAssay Description:Inhibition of full-length human N-terminal FLAG/His-tagged KDM5C (2 to 1560 residues) expressed in baculovirus infected Sf9 insect cells using H3(1-2...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668HPRPubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50095446(CHEMBL3590426)copy SMILEScopy InChI
Affinity DataIC50: 9.24E+3nMAssay Description:Inhibition of human N-terminal FLAG/His-tagged KDM5B (2 to 751 residues) expressed in baculovirus infected Sf9 insect cells using H3(1-21)K4(Me3)-GGK...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668HPRPubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM195608(CPI-455)copy SMILEScopy InChI
Affinity DataIC50: 1.43E+4nMAssay Description:Inhibition of human C-terminal FLAG-tagged KDM6B (1043 to end residues) expressed in baculovirus infected Sf9 insect cells using H3(21-44)-K27(Me3)-G...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668HPRPubMed
TargetLysine-specific demethylase 4A(Homo sapiens (Human))
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50532173(CHEMBL4536443)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human N-terminal His-tagged KDM4A (1 to 350 residues) expressed in Escherichia coli using H3(21-44)-K36(Me3)-GK(Biotin)/2-OG as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668HPRPubMed
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50095446(CHEMBL3590426)copy SMILEScopy InChI
Affinity DataIC50: 2.89E+4nMAssay Description:Inhibition of full-length human N-terminal FLAG/His-tagged KDM5C (2 to 1560 residues) expressed in baculovirus infected Sf9 insect cells using H3(1-2...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668HPRPubMed
TargetLysine-specific demethylase 2A(Homo sapiens (Human))
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50532173(CHEMBL4536443)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human N-terminal FLAG/Avi-tagged KDM2A (2 to 700 residues) expressed in baculovirus infected Sf9 insect cells using H3(21-44)-K36(Me2)-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668HPRPubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50532173(CHEMBL4536443)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human C-terminal FLAG-tagged KDM6B (1043 to end residues) expressed in baculovirus infected Sf9 insect cells using H3(21-44)-K27(Me3)-G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668HPRPubMed
TargetLysine-specific demethylase 2A(Homo sapiens (Human))
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50532176(CHEMBL4542928)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human N-terminal FLAG/Avi-tagged KDM2A (2 to 700 residues) expressed in baculovirus infected Sf9 insect cells using H3(21-44)-K36(Me2)-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668HPRPubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50532176(CHEMBL4542928)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human C-terminal FLAG-tagged KDM6B (1043 to end residues) expressed in baculovirus infected Sf9 insect cells using H3(21-44)-K27(Me3)-G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668HPRPubMed
TargetHistone lysine demethylase PHF8(Homo sapiens (Human))
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50532173(CHEMBL4536443)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human N-terminal FLAG-tagged KDM7B (2 to 525 residues) expressed in baculovirus infected Sf9 insect cells using H3(1-21)K9(Me2)-GGK(Bio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668HPRPubMed
TargetHistone lysine demethylase PHF8(Homo sapiens (Human))
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50532176(CHEMBL4542928)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human N-terminal FLAG-tagged KDM7B (2 to 525 residues) expressed in baculovirus infected Sf9 insect cells using H3(1-21)K9(Me2)-GGK(Bio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668HPRPubMed
TargetLysine-specific demethylase 3A(Homo sapiens (Human))
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50532176(CHEMBL4542928)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human N-terminal FLAG-tagged KDM3A (2 to 1321 residues) expressed in baculovirus infected Sf9 insect cells using H3(1-21)K9(Me1)-GGK(Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668HPRPubMed
* indicates data uncertainty>20%