Compile Data Set for Download or QSAR

Found 62 hits of Enzyme Inhibition Constant Data   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM164638(BDBM166759 | US10604504, Example 223 | US11623921,...)copy SMILES
Affinity DataKi:  116nMAssay Description:Inhibition of His-tagged BTK (unknown origin) after 1.5 hrs by HTRF analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M66PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...)copy SMILEScopy InChI
Affinity DataKi:  425nMAssay Description:Inhibition of His-tagged BTK (unknown origin) after 1.5 hrs by HTRF analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM166831(US10604504, Example 242 | US11623921, Example 242 ...)copy SMILES
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of recombinant human BTK using fluoresceinated peptide as substrate after 60 mins fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M66PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...)copy SMILEScopy InChI
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of recombinant human BTK using fluoresceinated peptide as substrate after 60 mins fluorescence assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM164638(BDBM166759 | US10604504, Example 223 | US11623921,...)copy SMILES
Affinity DataIC50: 0.100nMAssay Description:Inhibition of recombinant human BTK using fluoresceinated peptide as substrate after 60 mins fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M66PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM165319(US10604504, Example 115 | US11623921, Example 115 ...)copy SMILES
Affinity DataIC50: 0.140nMAssay Description:Inhibition of recombinant human BTK using fluoresceinated peptide as substrate after 60 mins fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M66PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM164638(BDBM166759 | US10604504, Example 223 | US11623921,...)copy SMILES
Affinity DataIC50: 0.300nMAssay Description:Inhibition of BTK in human peripheral B cells assessed as reduction in CD86 surface expressionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M66PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM164638(BDBM166759 | US10604504, Example 223 | US11623921,...)copy SMILES
Affinity DataIC50: 0.300nMAssay Description:Inhibition of BTK in human PBMC assessed as reduction in TNFalpha expressionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M66PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM165320(US10604504, Example 116 | US11623921, Example 116 ...)copy SMILES
Affinity DataIC50: 0.520nMAssay Description:Inhibition of recombinant human BTK using fluoresceinated peptide as substrate after 60 mins fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M66PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM165463(US10604504, Example 141 | US11623921, Example 141 ...)copy SMILES
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant human BTK using fluoresceinated peptide as substrate after 60 mins fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M66PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM165318(US10604504, Example 114 | US11623921, Example 114 ...)copy SMILEScopy InChI
Affinity DataIC50: 0.850nMAssay Description:Inhibition of recombinant human BTK using fluoresceinated peptide as substrate after 60 mins fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M66PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM164638(BDBM166759 | US10604504, Example 223 | US11623921,...)copy SMILES
Affinity DataIC50: 0.900nMAssay Description:Inhibition of BTK in human memory B cells assessed as reduction in CD86 surface expressionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M66PubMed
TargetTyrosine-protein kinase Tec(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM164638(BDBM166759 | US10604504, Example 223 | US11623921,...)copy SMILES
Affinity DataIC50: 0.900nMAssay Description:Inhibition of TEC (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M66PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM165465(US10604504, Example 143 | US11623921, Example 143 ...)copy SMILES
Affinity DataIC50: 1.20nMAssay Description:Inhibition of recombinant human BTK using fluoresceinated peptide as substrate after 60 mins fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M66PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM165461(US10604504, Example 139 | US11623921, Example 139 ...)copy SMILES
Affinity DataIC50: 1.40nMAssay Description:Inhibition of recombinant human BTK using fluoresceinated peptide as substrate after 60 mins fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M66PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM165321(US10604504, Example 117 | US11623921, Example 117 ...)copy SMILES
Affinity DataIC50: 1.40nMAssay Description:Inhibition of recombinant human BTK using fluoresceinated peptide as substrate after 60 mins fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M66PubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM164638(BDBM166759 | US10604504, Example 223 | US11623921,...)copy SMILES
Affinity DataIC50: 1.5nMAssay Description:Inhibition of BMX (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M66PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50540957(CHEMBL4640555)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of recombinant human BTK using fluoresceinated peptide as substrate after 60 mins fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M66PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM166831(US10604504, Example 242 | US11623921, Example 242 ...)copy SMILES
Affinity DataIC50: 1.60nMAssay Description:Inhibition of BTK in human Ramos B cells assessed as reduction in BCR-stimulated calcium flux after 1 hr in dark condition measured for 180 secMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M66PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50540958(CHEMBL4649284)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Inhibition of recombinant human BTK using fluoresceinated peptide as substrate after 60 mins fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M66PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM165283(US10604504, Example 93 | US11623921, Example 79 | ...)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Inhibition of recombinant human BTK using fluoresceinated peptide as substrate after 60 mins fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M66PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM165287(US10604504, Example 83 | US11623921, Example 83 | ...)copy SMILES
Affinity DataIC50: 3.30nMAssay Description:Inhibition of recombinant human BTK using fluoresceinated peptide as substrate after 60 mins fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M66PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM165462(US10604504, Example 140 | US11623921, Example 140 ...)copy SMILES
Affinity DataIC50: 3.5nMAssay Description:Inhibition of recombinant human BTK using fluoresceinated peptide as substrate after 60 mins fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M66PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM165286(US10604504, Example 82 | US11623921, Example 82 | ...)copy SMILES
Affinity DataIC50: 4.20nMAssay Description:Inhibition of recombinant human BTK using fluoresceinated peptide as substrate after 60 mins fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M66PubMed
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM164638(BDBM166759 | US10604504, Example 223 | US11623921,...)copy SMILES
Affinity DataIC50: 5nMAssay Description:Inhibition of TXK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M66PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM165323(US10604504, Example 119 | US11623921, Example 119 ...)copy SMILES
Affinity DataIC50: 6.5nMAssay Description:Inhibition of recombinant human BTK using fluoresceinated peptide as substrate after 60 mins fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M66PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50540957(CHEMBL4640555)copy SMILEScopy InChI
Affinity DataIC50: 6.90nMAssay Description:Inhibition of BTK in human Ramos B cells assessed as reduction in BCR-stimulated calcium flux after 1 hr in dark condition measured for 180 secMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M66PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM164638(BDBM166759 | US10604504, Example 223 | US11623921,...)copy SMILES
Affinity DataIC50: 7.20nMAssay Description:Inhibition of BTK in human Ramos B cells assessed as reduction in BCR-stimulated calcium flux after 1 hr in dark condition measured for 180 secMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M66PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM165323(US10604504, Example 119 | US11623921, Example 119 ...)copy SMILES
Affinity DataIC50: 7.20nMAssay Description:Inhibition of BTK in human Ramos B cells assessed as reduction in BCR-stimulated calcium flux after 1 hr in dark condition measured for 180 secMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M66PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM165291(US10604504, Example 87 | US11623921, Example 87 | ...)copy SMILES
Affinity DataIC50: 8.40nMAssay Description:Inhibition of recombinant human BTK using fluoresceinated peptide as substrate after 60 mins fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M66PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50540958(CHEMBL4649284)copy SMILEScopy InChI
Affinity DataIC50: 9.40nMAssay Description:Inhibition of BTK in human Ramos B cells assessed as reduction in BCR-stimulated calcium flux after 1 hr in dark condition measured for 180 secMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M66PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM164638(BDBM166759 | US10604504, Example 223 | US11623921,...)copy SMILES
Affinity DataIC50: 11nMAssay Description:Inhibition of BTK in human peripheral B cells assessed as reduction in CD69 surface expression by whole blood assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M66PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of BTK in human Ramos B cells assessed as reduction in BCR-stimulated calcium flux after 1 hr in dark condition measured for 180 secMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM165463(US10604504, Example 141 | US11623921, Example 141 ...)copy SMILES
Affinity DataIC50: 15nMAssay Description:Inhibition of BTK in human Ramos B cells assessed as reduction in BCR-stimulated calcium flux after 1 hr in dark condition measured for 180 secMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M66PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM165318(US10604504, Example 114 | US11623921, Example 114 ...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of BTK in human Ramos B cells assessed as reduction in BCR-stimulated calcium flux after 1 hr in dark condition measured for 180 secMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M66PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM165319(US10604504, Example 115 | US11623921, Example 115 ...)copy SMILES
Affinity DataIC50: 18nMAssay Description:Inhibition of BTK in human Ramos B cells assessed as reduction in BCR-stimulated calcium flux after 1 hr in dark condition measured for 180 secMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M66PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM165463(US10604504, Example 141 | US11623921, Example 141 ...)copy SMILES
Affinity DataIC50: 22nMAssay Description:Inhibition of BTK in human whole blood cells after 120 mins by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M66PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM165321(US10604504, Example 117 | US11623921, Example 117 ...)copy SMILES
Affinity DataIC50: 26nMAssay Description:Inhibition of BTK in human Ramos B cells assessed as reduction in BCR-stimulated calcium flux after 1 hr in dark condition measured for 180 secMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M66PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM165465(US10604504, Example 143 | US11623921, Example 143 ...)copy SMILES
Affinity DataIC50: 28nMAssay Description:Inhibition of BTK in human Ramos B cells assessed as reduction in BCR-stimulated calcium flux after 1 hr in dark condition measured for 180 secMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M66PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM165310(US10604504, Example 106 | US11623921, Example 106 ...)copy SMILES
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant human BTK using fluoresceinated peptide as substrate after 60 mins fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M66PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of HER4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M66PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of HER1 (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM165461(US10604504, Example 139 | US11623921, Example 139 ...)copy SMILES
Affinity DataIC50: 30nMAssay Description:Inhibition of BTK in human Ramos B cells assessed as reduction in BCR-stimulated calcium flux after 1 hr in dark condition measured for 180 secMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M66PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM165320(US10604504, Example 116 | US11623921, Example 116 ...)copy SMILES
Affinity DataIC50: 40nMAssay Description:Inhibition of BTK in human Ramos B cells assessed as reduction in BCR-stimulated calcium flux after 1 hr in dark condition measured for 180 secMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M66PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM165283(US10604504, Example 93 | US11623921, Example 79 | ...)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Inhibition of BTK in human Ramos B cells assessed as reduction in BCR-stimulated calcium flux after 1 hr in dark condition measured for 180 secMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M66PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM165463(US10604504, Example 141 | US11623921, Example 141 ...)copy SMILES
Affinity DataIC50: 47nMAssay Description:Inhibition of BTK in human whole blood cells after 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M66PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...)copy SMILEScopy InChI
Affinity DataIC50: 58nMAssay Description:Inhibition of BTK in human whole blood cells after 120 mins by ELISAMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM165295(US10604504, Example 91 | US11623921, Example 91 | ...)copy SMILES
Affinity DataIC50: 59nMAssay Description:Inhibition of recombinant human BTK using fluoresceinated peptide as substrate after 60 mins fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M66PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM165463(US10604504, Example 141 | US11623921, Example 141 ...)copy SMILES
Affinity DataIC50: 90nMAssay Description:Inhibition of BTK in human whole blood cells after 30 mins by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M66PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM165287(US10604504, Example 83 | US11623921, Example 83 | ...)copy SMILES
Affinity DataIC50: 100nMAssay Description:Inhibition of BTK in human Ramos B cells assessed as reduction in BCR-stimulated calcium flux after 1 hr in dark condition measured for 180 secMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5M66PubMed
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