Compile Data Set for Download or QSAR

Found 112 hits of Enzyme Inhibition Constant Data   

LigandPNGBDBM50512300(CHEMBL4575012)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed
LigandPNGBDBM50512313(CHEMBL4435694)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed
LigandPNGBDBM50512302(CHEMBL4441262)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed
LigandPNGBDBM50512303(CHEMBL4582480)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed
LigandPNGBDBM50512301(CHEMBL4570812)copy SMILEScopy InChI
Affinity DataIC50: 3.90nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed
LigandPNGBDBM50512309(CHEMBL4546631)copy SMILEScopy InChI
Affinity DataIC50: 4.30nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed
LigandPNGBDBM50512310(CHEMBL4468074)copy SMILEScopy InChI
Affinity DataIC50: 5.20nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed
LigandPNGBDBM333914(6-{[(3S)-1- (cyclopropylcarbonyl)pyrrolidin- 3-yl]...)copy SMILEScopy InChI
Affinity DataIC50: 5.30nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed
LigandPNGBDBM50512295(CHEMBL4447337)copy SMILEScopy InChI
Affinity DataIC50: 6.30nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
LigandPNGBDBM50512307(CHEMBL4483321)copy SMILEScopy InChI
Affinity DataIC50: 9.20nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed
LigandPNGBDBM50512305(CHEMBL4462856)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed
LigandPNGBDBM50512313(CHEMBL4435694)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of PI3Kdelta in human Ramos cells assessed as reduction in anti-IgM-antibody-induced phosphorylation of AKT at Ser473 residue preincubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed
LigandPNGBDBM50512308(CHEMBL4474475)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed
LigandPNGBDBM50512300(CHEMBL4575012)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of PI3Kdelta in human Ramos cells assessed as reduction in anti-IgM-antibody-induced phosphorylation of AKT at Ser473 residue preincubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed
LigandPNGBDBM50512311(CHEMBL4483370)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed
LigandPNGBDBM50512303(CHEMBL4582480)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of PI3Kdelta in human Ramos cells assessed as reduction in anti-IgM-antibody-induced phosphorylation of AKT at Ser473 residue preincubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed
LigandPNGBDBM50512298(CHEMBL4583776)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed
LigandPNGBDBM50512302(CHEMBL4441262)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of PI3Kdelta in human Ramos cells assessed as reduction in anti-IgM-antibody-induced phosphorylation of AKT at Ser473 residue preincubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed
LigandPNGBDBM50512296(CHEMBL4445755)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed
LigandPNGBDBM50512314(CHEMBL4591038)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed
LigandPNGBDBM50512313(CHEMBL4435694)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110alpha/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed
LigandPNGBDBM50512300(CHEMBL4575012)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110alpha/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed
LigandPNGBDBM50512313(CHEMBL4435694)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of PI3Kdelta in human whole blood assessed as reduction in anti-CD79b antibody-induced CD69 expression preincubated for 60 mins followed b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed
LigandPNGBDBM50512312(CHEMBL4522133)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed
LigandPNGBDBM50512309(CHEMBL4546631)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Inhibition of PI3Kdelta in human Ramos cells assessed as reduction in anti-IgM-antibody-induced phosphorylation of AKT at Ser473 residue preincubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed
LigandPNGBDBM50512306(CHEMBL4528393)copy SMILEScopy InChI
Affinity DataIC50: 57nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed
LigandPNGBDBM50512301(CHEMBL4570812)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Inhibition of PI3Kdelta in human Ramos cells assessed as reduction in anti-IgM-antibody-induced phosphorylation of AKT at Ser473 residue preincubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed
LigandPNGBDBM50512295(CHEMBL4447337)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibition of PI3Kdelta in human Ramos cells assessed as reduction in anti-IgM-antibody-induced phosphorylation of AKT at Ser473 residue preincubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
LigandPNGBDBM50512297(CHEMBL4435158)copy SMILEScopy InChI
Affinity DataIC50: 68nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed
LigandPNGBDBM50512305(CHEMBL4462856)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110alpha/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed
LigandPNGBDBM50512302(CHEMBL4441262)copy SMILEScopy InChI
Affinity DataIC50: 94nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110alpha/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed
LigandPNGBDBM50512310(CHEMBL4468074)copy SMILEScopy InChI
Affinity DataIC50: 106nMAssay Description:Inhibition of PI3Kdelta in human Ramos cells assessed as reduction in anti-IgM-antibody-induced phosphorylation of AKT at Ser473 residue preincubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed
LigandPNGBDBM50512309(CHEMBL4546631)copy SMILEScopy InChI
Affinity DataIC50: 121nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110alpha/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed
LigandPNGBDBM50512303(CHEMBL4582480)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of PI3Kdelta in human whole blood assessed as reduction in antihuman IgE antibody-stimulated CD63 expression preincubated for 30 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed
LigandPNGBDBM50512305(CHEMBL4462856)copy SMILEScopy InChI
Affinity DataIC50: 153nMAssay Description:Inhibition of PI3Kdelta in human Ramos cells assessed as reduction in anti-IgM-antibody-induced phosphorylation of AKT at Ser473 residue preincubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed
LigandPNGBDBM333914(6-{[(3S)-1- (cyclopropylcarbonyl)pyrrolidin- 3-yl]...)copy SMILEScopy InChI
Affinity DataIC50: 169nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110alpha/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed
LigandPNGBDBM50512296(CHEMBL4445755)copy SMILEScopy InChI
Affinity DataIC50: 187nMAssay Description:Inhibition of PI3Kdelta in human Ramos cells assessed as reduction in anti-IgM-antibody-induced phosphorylation of AKT at Ser473 residue preincubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed
LigandPNGBDBM333914(6-{[(3S)-1- (cyclopropylcarbonyl)pyrrolidin- 3-yl]...)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Inhibition of PI3Kdelta in human Ramos cells assessed as reduction in anti-IgM-antibody-induced phosphorylation of AKT at Ser473 residue preincubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed
LigandPNGBDBM50512303(CHEMBL4582480)copy SMILEScopy InChI
Affinity DataIC50: 262nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110alpha/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed
LigandPNGBDBM50512301(CHEMBL4570812)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110alpha/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed
LigandPNGBDBM50512310(CHEMBL4468074)copy SMILEScopy InChI
Affinity DataIC50: 274nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110alpha/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed
LigandPNGBDBM334245((3-((8-(1-ethyl-5-methyl-1H- pyrazol-4-yl)-9-methy...)copy SMILEScopy InChI
Affinity DataIC50: 294nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed
LigandPNGBDBM50512307(CHEMBL4483321)copy SMILEScopy InChI
Affinity DataIC50: 309nMAssay Description:Inhibition of PI3Kdelta in human Ramos cells assessed as reduction in anti-IgM-antibody-induced phosphorylation of AKT at Ser473 residue preincubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed
LigandPNGBDBM50512313(CHEMBL4435694)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:Inhibition of PI3Kdelta in human whole blood assessed as reduction in antihuman IgE antibody-stimulated CD63 expression preincubated for 30 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed
LigandPNGBDBM50512307(CHEMBL4483321)copy SMILEScopy InChI
Affinity DataIC50: 338nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110alpha/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed
LigandPNGBDBM50512301(CHEMBL4570812)copy SMILEScopy InChI
Affinity DataIC50: 360nMAssay Description:Inhibition of PI3Kdelta in human whole blood assessed as reduction in anti-CD79b antibody-induced CD69 expression preincubated for 60 mins followed b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed
LigandPNGBDBM50512298(CHEMBL4583776)copy SMILEScopy InChI
Affinity DataIC50: 406nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110alpha/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed
LigandPNGBDBM50512301(CHEMBL4570812)copy SMILEScopy InChI
Affinity DataIC50: 415nMAssay Description:Inhibition of PI3Kdelta in human whole blood assessed as reduction in antihuman IgE antibody-stimulated CD63 expression preincubated for 30 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed
LigandPNGBDBM50512295(CHEMBL4447337)copy SMILEScopy InChI
Affinity DataIC50: 450nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110alpha/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed
LigandPNGBDBM50512311(CHEMBL4483370)copy SMILEScopy InChI
Affinity DataIC50: 453nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110alpha/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed
Displayed 1 to 50 (of 112 total ) | Next | Last >>* indicates data uncertainty>20%