Compile Data Set for Download or QSAR

Found 24 hits of Enzyme Inhibition Constant Data   

TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50505262(CHEMBL4559408)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Inhibition of ROMK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9N7JPubMed
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50505262(CHEMBL4559408)copy SMILEScopy InChI
Affinity DataKi:  8.20nMAssay Description:Inhibition GIRK1/4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9N7JPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Rattus norvegicus (Rat))
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM350315(US10208064, Example 30)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of rat ROMK1 expressed in HEK293 cells by Tl+ flux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9N7JPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50505266(CHEMBL4548110)copy SMILEScopy InChI
Affinity DataIC50: 6.20nMAssay Description:Inhibition of human ROMK1 expressed in CHO cells by Tl+ flux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9N7JPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50505267(CHEMBL4563446)copy SMILEScopy InChI
Affinity DataIC50: 6.60nMAssay Description:Inhibition of human ROMK1 expressed in CHO cells by Tl+ flux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9N7JPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50505268(CHEMBL4549009)copy SMILEScopy InChI
Affinity DataIC50: 6.60nMAssay Description:Inhibition of human ROMK1 expressed in CHO cells by Tl+ flux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9N7JPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50505271(CHEMBL4462473)copy SMILEScopy InChI
Affinity DataIC50: 8.80nMAssay Description:Inhibition of human ROMK1 expressed in CHO cells by Tl+ flux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9N7JPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Rattus norvegicus (Rat))
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM350282(US10208064, Example 2)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of rat ROMK1 expressed in HEK293 cells by Tl+ flux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9N7JPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Rattus norvegicus (Rat))
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM350300(US10208064, Example 19)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of rat ROMK1 expressed in HEK293 cells by Tl+ flux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9N7JPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Rattus norvegicus (Rat))
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50505263(CHEMBL4586813)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of rat ROMK1 expressed in HEK293 cells by Tl+ flux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9N7JPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50505265(CHEMBL4465260)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of human ROMK1 expressed in CHO cells by Tl+ flux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9N7JPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50505270(CHEMBL4447159)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of human ROMK1 expressed in CHO cells by Tl+ flux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9N7JPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Rattus norvegicus (Rat))
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50505261(CHEMBL4456474)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Inhibition of rat ROMK1 expressed in HEK293 cells by Tl+ flux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9N7JPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50204280(CHEMBL3987135 | US9573961, Example 15)copy SMILEScopy InChI
Affinity DataIC50: 57nMAssay Description:Inhibition of human ROMK1 expressed in HEK293 cells by Tl+ flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9N7JPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM290057(US9573961, Example 42)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of human ROMK1 expressed in HEK293 cells by Tl+ flux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9N7JPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50505264(CHEMBL4544141)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:Inhibition of human ROMK1 expressed in HEK293 cells by Tl+ flux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9N7JPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50204281(CHEMBL3933749)copy SMILEScopy InChI
Affinity DataIC50: 73nMAssay Description:Inhibition of human ROMK1 expressed in HEK293 cells by Tl+ flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9N7JPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Rattus norvegicus (Rat))
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50287521(CHEMBL2146753)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Inhibition of rat ROMK1 expressed in HEK293 cells by Tl+ flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9N7JPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Rattus norvegicus (Rat))
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM73215(7,13-bis(4-nitrobenzyl)-1,4,10-trioxa-7,13-diazacy...)copy SMILEScopy InChI
Affinity DataIC50: 294nMAssay Description:Inhibition of rat ROMK1 expressed in HEK293 cells by Tl+ flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9N7JPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Rattus norvegicus (Rat))
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50505269(CHEMBL1470194)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of rat ROMK1 expressed in HEK293 cells by Tl+ flux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9N7JPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM290057(US9573961, Example 42)copy SMILEScopy InChI
Affinity DataIC50: 1.48E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9N7JPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50204281(CHEMBL3933749)copy SMILEScopy InChI
Affinity DataIC50: 2.03E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9N7JPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50505264(CHEMBL4544141)copy SMILEScopy InChI
Affinity DataIC50: 2.11E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9N7JPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50204280(CHEMBL3987135 | US9573961, Example 15)copy SMILEScopy InChI
Affinity DataIC50: 7.59E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9N7JPubMed
* indicates data uncertainty>20%