Compile Data Set for Download or QSAR

Found 21 hits of Enzyme Inhibition Constant Data   

TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
University of Napoli Federico II

Curated by ChEMBL
LigandPNGBDBM50335390(CHEMBL1651630 | N-Hexoxypentyl-1-deoxynojirimycin)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of NLGase in human SH-SY5Y cells using MUG-Gluc as fluorogenic substrate preincubated for 30 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BBHPubMed
TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
University of Napoli Federico II

Curated by ChEMBL
LigandPNGBDBM50524479(CHEMBL4459011)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of NLGase in human SH-SY5Y cells using MUG-Gluc as fluorogenic substrate preincubated for 30 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BBHPubMed
TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
University of Napoli Federico II

Curated by ChEMBL
LigandPNGBDBM18358((2R,3R,4R,5S)-2-(hydroxymethyl)-1-nonylpiperidine-...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of NLGase in human SH-SY5Y cells using MUG-Gluc as fluorogenic substrate preincubated for 30 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BBHPubMed
TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
University of Napoli Federico II

Curated by ChEMBL
LigandPNGBDBM50299749((2R,3R,4R,5S)-1-[5-(Adamantan-1-ylmethoxy)-pentyl]...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of NLGase in human SH-SY5Y cells using MUG-Gluc as fluorogenic substrate preincubated for 30 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BBHPubMed
TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
University of Napoli Federico II

Curated by ChEMBL
LigandPNGBDBM50524480(CHEMBL4559665)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of NLGase in human SH-SY5Y cells using MUG-Gluc as fluorogenic substrate preincubated for 30 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BBHPubMed
TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
University of Napoli Federico II

Curated by ChEMBL
LigandPNGBDBM18355((2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of NLGase in human SH-SY5Y cells using MUG-Gluc as fluorogenic substrate preincubated for 30 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BBHPubMed
TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
University of Napoli Federico II

Curated by ChEMBL
LigandPNGBDBM50335387(CHEMBL1651633 | N-Nonoxypentyl-1-deoxynojirimycin)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of NLGase in human SH-SY5Y cells using MUG-Gluc as fluorogenic substrate preincubated for 30 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BBHPubMed
TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
University of Napoli Federico II

Curated by ChEMBL
LigandPNGBDBM50156357(2-Hydroxymethyl-1-nonyl-piperidine-3,4,5-triol | C...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of NLGase in human SH-SY5Y cells using MUG-Gluc as fluorogenic substrate preincubated for 30 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BBHPubMed
TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
University of Napoli Federico II

Curated by ChEMBL
LigandPNGBDBM50524486(CHEMBL4577406)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibition of NLGase in human SH-SY5Y cells using MUG-Gluc as fluorogenic substrate preincubated for 30 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BBHPubMed
TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
University of Napoli Federico II

Curated by ChEMBL
LigandPNGBDBM50524485(CHEMBL4435506)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:Inhibition of NLGase in human SH-SY5Y cells using MUG-Gluc as fluorogenic substrate preincubated for 30 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BBHPubMed
TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
University of Napoli Federico II

Curated by ChEMBL
LigandPNGBDBM50524481(CHEMBL4459494)copy SMILEScopy InChI
Affinity DataIC50: 137nMAssay Description:Inhibition of NLGase in human SH-SY5Y cells using MUG-Gluc as fluorogenic substrate preincubated for 30 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BBHPubMed
TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
University of Napoli Federico II

Curated by ChEMBL
LigandPNGBDBM50524484(CHEMBL187262)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Inhibition of NLGase in human SH-SY5Y cells using MUG-Gluc as fluorogenic substrate preincubated for 30 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BBHPubMed
TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
University of Napoli Federico II

Curated by ChEMBL
LigandPNGBDBM50524482(CHEMBL4460711)copy SMILEScopy InChI
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of NLGase in human SH-SY5Y cells using MUG-Gluc as fluorogenic substrate preincubated for 30 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BBHPubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University of Napoli Federico II

Curated by ChEMBL
LigandPNGBDBM50335390(CHEMBL1651630 | N-Hexoxypentyl-1-deoxynojirimycin)copy SMILEScopy InChI
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of GCase in human SH-SY5Y cells using MUG-Gluc as fluorogenic substrate preincubated for 30 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BBHPubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University of Napoli Federico II

Curated by ChEMBL
LigandPNGBDBM18358((2R,3R,4R,5S)-2-(hydroxymethyl)-1-nonylpiperidine-...)copy SMILEScopy InChI
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of GCase in human SH-SY5Y cells using MUG-Gluc as fluorogenic substrate preincubated for 30 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
University of Napoli Federico II

Curated by ChEMBL
LigandPNGBDBM50243651(CHEMBL4061367)copy SMILEScopy InChI
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of NLGase in human SH-SY5Y cells using MUG-Gluc as fluorogenic substrate preincubated for 30 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BBHPubMed
TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
University of Napoli Federico II

Curated by ChEMBL
LigandPNGBDBM50524483(CHEMBL4435540)copy SMILEScopy InChI
Affinity DataIC50: 3.67E+4nMAssay Description:Inhibition of NLGase in human SH-SY5Y cells using MUG-Gluc as fluorogenic substrate preincubated for 30 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BBHPubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University of Napoli Federico II

Curated by ChEMBL
LigandPNGBDBM50243651(CHEMBL4061367)copy SMILEScopy InChI
Affinity DataIC50: 6.20E+4nMAssay Description:Inhibition of GCase in human SH-SY5Y cells using MUG-Gluc as fluorogenic substrate preincubated for 30 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BBHPubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University of Napoli Federico II

Curated by ChEMBL
LigandPNGBDBM18355((2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-...)copy SMILEScopy InChI
Affinity DataIC50: 1.18E+5nMAssay Description:Inhibition of GCase in human SH-SY5Y cells using MUG-Gluc as fluorogenic substrate preincubated for 30 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University of Napoli Federico II

Curated by ChEMBL
LigandPNGBDBM50524482(CHEMBL4460711)copy SMILEScopy InChI
Affinity DataIC50: 1.36E+5nMAssay Description:Inhibition of GCase in human SH-SY5Y cells using MUG-Gluc as fluorogenic substrate preincubated for 30 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BBHPubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University of Napoli Federico II

Curated by ChEMBL
LigandPNGBDBM50524483(CHEMBL4435540)copy SMILEScopy InChI
Affinity DataIC50: 6.03E+5nMAssay Description:Inhibition of GCase in human SH-SY5Y cells using MUG-Gluc as fluorogenic substrate preincubated for 30 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BBHPubMed
* indicates data uncertainty>20%