Compile Data Set for Download or QSAR

Found 84 hits of Enzyme Inhibition Constant Data   

TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50247556(CHEMBL4104117)copy SMILEScopy InChI
Affinity DataIC50: 0.290nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50274998(CHEMBL4126811)copy SMILEScopy InChI
Affinity DataIC50: 0.330nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 (1 to 1215 residues) expressed in baculovirus infected sf9 insect cells using p53 (379 to...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50252391(CHEMBL4080014)copy SMILEScopy InChI
Affinity DataIC50: 0.810nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 (1 to 1215 residues) expressed in baculovirus infected sf9 insect cells using RHK-K(Ac)-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50513915(CHEMBL4447715)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human HDAC6 expressed in HEK293T/17 cells using Ac-GAK(Ac)-AMC as substrate preincubated for 10 mins followed by substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 (1 to 1215 residues) expressed in baculovirus infected sf9 insect cells using p53 (379 to...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM417049(4-((6-chloro-3,4-dihydroquinolin-1(2H)-yl)methyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 (1 to 1215 residues) expressed in baculovirus infected sf9 insect cells using p53 (379 to...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM110036(US8609678, 2-((2-chlorophenyl)(phenyl)amino)-N-(7-...)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged HDAC6 expressed in baculovirus infected Sf9 insect cells assessed as decrease in re...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50261816(CHEMBL511749 | tert-butyl 4-(3-((7-(hydroxyamino)-...)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of recombinant full length C-terminal His/FLAG tagged human HDAC1 (1 to 482 residues) expressed in baculovirus infected sf9 insect cells u...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50398716(CHEMBL2179618 | US10227295, Compound 5g | US940985...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant human HDAC6 expressed in HEK293T/17 cells using Ac-GAK(Ac)-AMC as substrate preincubated for 10 mins followed by substrate ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50439674(RICOLINOSTAT | US10858323, Compound 2 | US11207431...)copy SMILEScopy InChI
Affinity DataIC50: 4.70nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged HDAC6 expressed in baculovirus infected Sf9 insect cells assessed as decrease in re...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50398716(CHEMBL2179618 | US10227295, Compound 5g | US940985...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 (1 to 1215 residues) expressed in baculovirus infected sf9 insect cells using p53 (379 to...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50513919(CHEMBL4457162)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50513920(CHEMBL4554511)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 (1 to 1215 residues) expressed in baculovirus infected sf9 insect cells using p53 (379 to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50252392(CHEMBL4069287)copy SMILEScopy InChI
Affinity DataIC50: 8.20nMAssay Description:Inhibition of recombinant full-length human HDAC6 expressed in baculovirus infected sf9 insect cells using Fluor de Lys as substrate preincubated for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant full length C-terminal His/FLAG tagged human HDAC1 (1 to 482 residues) expressed in baculovirus infected sf9 insect cells u...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50513925(CHEMBL4556111)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 (1 to 1215 residues) expressed in baculovirus infected sf9 insect cells using p53 (379 to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50513916(CHEMBL4469488)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human HDAC6 expressed in HEK293T/17 cells using Ac-GAK(Ac)-AMC as substrate preincubated for 10 mins followed by substrate ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50513918(CHEMBL4462652)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant HDAC6 using fluorogenic substrate incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50261816(CHEMBL511749 | tert-butyl 4-(3-((7-(hydroxyamino)-...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 (1 to 1215 residues) expressed in baculovirus infected sf9 insect cells using p53 (379 to...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50513926(CHEMBL4483795)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 (1 to 1215 residues) expressed in baculovirus infected sf9 insect cells using p53 (379 to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50513915(CHEMBL4447715)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 (1 to 1215 residues) expressed in baculovirus infected sf9 insect cells using p53 (379 to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50513917(CHEMBL4520424)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 (1 to 1215 residues) expressed in baculovirus infected sf9 insect cells using p53 (379 to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50252388(CHEMBL4079541)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged HDAC6 expressed in baculovirus infected Sf9 insect cells assessed as decrease in re...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50513915(CHEMBL4447715)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of recombinant human HDAC1 expressed in HEK293T/17 cells using Ac-GAK(Ac)-AMC as substrate preincubated for 10 mins followed by substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM110036(US8609678, 2-((2-chlorophenyl)(phenyl)amino)-N-(7-...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant human full length C-terminal His/FLAG-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells assessed as decrease ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50439674(RICOLINOSTAT | US10858323, Compound 2 | US11207431...)copy SMILEScopy InChI
Affinity DataIC50: 58nMAssay Description:Inhibition of recombinant human full length C-terminal His/FLAG-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells assessed as decrease ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50369345(CHEMBL4165724 | US11207431, Example 1 | US11890356...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant HDAC6 using fluorogenic HDAC substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50513916(CHEMBL4469488)copy SMILEScopy InChI
Affinity DataIC50: 75nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 (1 to 1215 residues) expressed in baculovirus infected sf9 insect cells using p53 (379 to...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM417049(4-((6-chloro-3,4-dihydroquinolin-1(2H)-yl)methyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of HDAC6 CD2 (unknown origin) expressed in HEK293 cells cotransfected with nano-luciferase incubated for 2 hrs followed by NanoBRET NanoGl...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 122nMAssay Description:Inhibition of HDAC1 (unknown origin) expressed in HEK293 cells cotransfected with nano-luciferase incubated for 2 hrs followed by NanoBRET NanoGlo Su...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50513921(CHEMBL4584312)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 (1 to 1215 residues) expressed in baculovirus infected sf9 insect cells using p53 (379 to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50513915(CHEMBL4447715)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant full length C-terminal His/FLAG tagged human HDAC1 (1 to 482 residues) expressed in baculovirus infected sf9 insect cells u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50513928(CHEMBL4470946)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 (1 to 1215 residues) expressed in baculovirus infected sf9 insect cells using p53 (379 to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 241nMAssay Description:Inhibition of HDAC6 CD2 (unknown origin) expressed in HEK293 cells cotransfected with nano-luciferase incubated for 2 hrs followed by NanoBRET NanoGl...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMedDrugBank
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50513917(CHEMBL4520424)copy SMILEScopy InChI
Affinity DataIC50: 307nMAssay Description:Inhibition of recombinant full length C-terminal His/FLAG tagged human HDAC1 (1 to 482 residues) expressed in baculovirus infected sf9 insect cells u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50398716(CHEMBL2179618 | US10227295, Compound 5g | US940985...)copy SMILEScopy InChI
Affinity DataIC50: 360nMAssay Description:Inhibition of recombinant human HDAC1 expressed in HEK293T/17 cells using Ac-GAK(Ac)-AMC as substrate preincubated for 10 mins followed by substrate ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50274998(CHEMBL4126811)copy SMILEScopy InChI
Affinity DataIC50: 436nMAssay Description:Inhibition of recombinant full length C-terminal His/FLAG tagged human HDAC1 (1 to 482 residues) expressed in baculovirus infected sf9 insect cells u...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50513915(CHEMBL4447715)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant human HDAC7 expressed in HEK293T/17 cells using Boc-Lys(TFA)-AMC as substrate preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50513916(CHEMBL4469488)copy SMILEScopy InChI
Affinity DataIC50: 504nMAssay Description:Inhibition of HDAC6 CD2 (unknown origin) expressed in HEK293 cells cotransfected with nano-luciferase incubated for 2 hrs followed by NanoBRET NanoGl...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50513924(CHEMBL4551620)copy SMILEScopy InChI
Affinity DataIC50: 690nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 (1 to 1215 residues) expressed in baculovirus infected sf9 insect cells using p53 (379 to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50513915(CHEMBL4447715)copy SMILEScopy InChI
Affinity DataIC50: 920nMAssay Description:Inhibition of recombinant human HDAC8 expressed in HEK293T/17 cells using Boc-Lys(TFA)-AMC as substrate preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50369345(CHEMBL4165724 | US11207431, Example 1 | US11890356...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant HDAC1 using fluorogenic HDAC substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
TargetHistone deacetylase 11(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50513915(CHEMBL4447715)copy SMILEScopy InChI
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of recombinant human HDAC11 expressed in HEK293T/17 cells using Boc-Lys(TFA)-AMC as substrate preincubated for 10 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50252388(CHEMBL4079541)copy SMILEScopy InChI
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of recombinant human full length C-terminal His/FLAG-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells assessed as decrease ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50513916(CHEMBL4469488)copy SMILEScopy InChI
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibition of recombinant human HDAC8 expressed in HEK293T/17 cells using Boc-Lys(TFA)-AMC as substrate preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50513927(CHEMBL4526191)copy SMILEScopy InChI
Affinity DataIC50: 1.35E+3nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 (1 to 1215 residues) expressed in baculovirus infected sf9 insect cells using p53 (379 to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50513916(CHEMBL4469488)copy SMILEScopy InChI
Affinity DataIC50: 1.39E+3nMAssay Description:Inhibition of recombinant human HDAC1 expressed in HEK293T/17 cells using Ac-GAK(Ac)-AMC as substrate preincubated for 10 mins followed by substrate ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50398716(CHEMBL2179618 | US10227295, Compound 5g | US940985...)copy SMILEScopy InChI
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibition of recombinant human HDAC8 expressed in HEK293T/17 cells using Boc-Lys(TFA)-AMC as substrate preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50513922(CHEMBL4589770)copy SMILEScopy InChI
Affinity DataIC50: 1.98E+3nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 (1 to 1215 residues) expressed in baculovirus infected sf9 insect cells using p53 (379 to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50513923(CHEMBL4473037)copy SMILEScopy InChI
Affinity DataIC50: 1.99E+3nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 (1 to 1215 residues) expressed in baculovirus infected sf9 insect cells using p53 (379 to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542RXHPubMed
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