Compile Data Set for Download or QSAR

Found 14 hits of Enzyme Inhibition Constant Data   

TargetType-1 angiotensin II receptor A(RAT)
Centre Hospitalier Universitaire Vaudois (CHUV) and University of Lausanne (UNIL)

Curated by ChEMBL
LigandPNGBDBM50049189(3-[4-(2-Ethyl-57-dimethyl-imidazo[45-b]pyridin-3-y...)copy SMILEScopy InChI
Affinity DataKi:  3.90nMAssay Description:Displacement of [125I]Ang II from AT1 receptor in rat liver membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20868NGPubMed
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
Centre Hospitalier Universitaire Vaudois (CHUV) and University of Lausanne (UNIL)

Curated by ChEMBL
LigandPNGBDBM50282396((S)-1-(4-Dimethylamino-3-methyl-benzyl)-5-diphenyl...)copy SMILEScopy InChI
Affinity DataKi:  12nMAssay Description:Inhibition of human AT1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20868NGPubMed
TargetType-1 angiotensin II receptor A(RAT)
Centre Hospitalier Universitaire Vaudois (CHUV) and University of Lausanne (UNIL)

Curated by ChEMBL
LigandPNGBDBM50514581(CHEMBL1885579)copy SMILEScopy InChI
Affinity DataKi:  1.70E+3nMAssay Description:Displacement of [125I]Ang II from AT1 receptor in rat SMC membranes incubated for 60 mins by gamma counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20868NGPubMed
TargetType-1 angiotensin II receptor A(RAT)
Centre Hospitalier Universitaire Vaudois (CHUV) and University of Lausanne (UNIL)

Curated by ChEMBL
LigandPNGBDBM50156173((1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]Ang II from AT1 receptor in rat liver membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20868NGPubMed
TargetType-2 angiotensin II receptor(Homo sapiens (Human))
Centre Hospitalier Universitaire Vaudois (CHUV) and University of Lausanne (UNIL)

Curated by ChEMBL
LigandPNGBDBM50282396((S)-1-(4-Dimethylamino-3-methyl-benzyl)-5-diphenyl...)copy SMILEScopy InChI
Affinity DataKi:  1.20E+5nMAssay Description:Inhibition of human AT2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20868NGPubMed
TargetProto-oncogene Mas(Homo sapiens)
Centre Hospitalier Universitaire Vaudois (CHUV) and University of Lausanne (UNIL)

Curated by ChEMBL
LigandPNGBDBM50514583(CHEMBL4578721)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Antagonist activity at N-terminal c-Myc tagged human MasR expressed in HEK293T cells by cAMP accumulation based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20868NGPubMed
TargetAngiotensin-converting enzyme 2(Homo sapiens (Human))
Centre Hospitalier Universitaire Vaudois (CHUV) and University of Lausanne (UNIL)

Curated by ChEMBL
LigandPNGBDBM21489((2S)-2-{[(1S)-1-carboxy-2-{1-[(3,5-dichlorophenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 0.440nMAssay Description:Inhibition of ACE2 (unknown origin)More data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor A(RAT)
Centre Hospitalier Universitaire Vaudois (CHUV) and University of Lausanne (UNIL)

Curated by ChEMBL
LigandPNGBDBM50369183(CHEMBL290214 | L-163491)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Displacement of [125I]Ang II from AT1 receptor in rat liver membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20868NGPubMed
TargetProto-oncogene Mas(Homo sapiens)
Centre Hospitalier Universitaire Vaudois (CHUV) and University of Lausanne (UNIL)

Curated by ChEMBL
LigandPNGBDBM50514584(CHEMBL4303593)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Agonist activity at N-terminal c-Myc tagged human MasR expressed in HEK293T cells assessed as reduction in forskolin-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20868NGPubMed
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
Centre Hospitalier Universitaire Vaudois (CHUV) and University of Lausanne (UNIL)

Curated by ChEMBL
LigandPNGBDBM50049182((S)-5-Benzyloxy-2-diphenylacetyl-6-methoxy-1,2,3,4...)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Inhibition of human AT1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20868NGPubMed
TargetType-2 angiotensin II receptor(RAT)
Centre Hospitalier Universitaire Vaudois (CHUV) and University of Lausanne (UNIL)

Curated by ChEMBL
LigandPNGBDBM50514582(CHEMBL155836)copy SMILEScopy InChI
Affinity DataIC50: 75nMAssay Description:Inhibition of rat AT2 receptorMore data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
Centre Hospitalier Universitaire Vaudois (CHUV) and University of Lausanne (UNIL)

Curated by ChEMBL
LigandPNGBDBM50514585(CHEMBL4448705)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human AT1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20868NGPubMed
TargetType-2 angiotensin II receptor(Homo sapiens (Human))
Centre Hospitalier Universitaire Vaudois (CHUV) and University of Lausanne (UNIL)

Curated by ChEMBL
LigandPNGBDBM50049182((S)-5-Benzyloxy-2-diphenylacetyl-6-methoxy-1,2,3,4...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human AT2 receptorMore data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor A(RAT)
Centre Hospitalier Universitaire Vaudois (CHUV) and University of Lausanne (UNIL)

Curated by ChEMBL
LigandPNGBDBM50514582(CHEMBL155836)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+6nMAssay Description:Inhibition of rat AT1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20868NGPubMed
* indicates data uncertainty>20%