Compile Data Set for Download or QSAR

Found 21 hits of Enzyme Inhibition Constant Data   

TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50538670(CHEMBL4642579)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human Src expressed in Escherichia coli BL21 using Abltide peptide as substrate incubated for 20 to 40 mins by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C21CTPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50538668(CHEMBL4634455 | US11518761, Example 159)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human Src expressed in Escherichia coli BL21 using Abltide peptide as substrate incubated for 20 to 40 mins by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C21CTPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50538669(CHEMBL4646408)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human Src expressed in Escherichia coli BL21 using Abltide peptide as substrate incubated for 20 to 40 mins by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C21CTPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50538670(CHEMBL4642579)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells by patch-clamp electrophysiology assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C21CTPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50538669(CHEMBL4646408)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells by patch-clamp electrophysiology assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C21CTPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50538668(CHEMBL4634455 | US11518761, Example 159)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells by patch-clamp electrophysiology assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C21CTPubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50538670(CHEMBL4642579)copy SMILEScopy InChI
Affinity DataEC50:  2.08E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate measured after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C21CTPubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50538668(CHEMBL4634455 | US11518761, Example 159)copy SMILEScopy InChI
Affinity DataEC50:  5.78E+3nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using S-mephenytoin as substrate measured after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C21CTPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50538669(CHEMBL4646408)copy SMILEScopy InChI
Affinity DataEC50:  5.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate measured after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C21CTPubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50538669(CHEMBL4646408)copy SMILEScopy InChI
Affinity DataEC50:  5.00E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using S-mephenytoin as substrate measured after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C21CTPubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50538669(CHEMBL4646408)copy SMILEScopy InChI
Affinity DataEC50:  5.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate measured after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C21CTPubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50538670(CHEMBL4642579)copy SMILEScopy InChI
Affinity DataEC50:  5.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate measured after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C21CTPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50538668(CHEMBL4634455 | US11518761, Example 159)copy SMILEScopy InChI
Affinity DataEC50:  5.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate measured after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C21CTPubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50538668(CHEMBL4634455 | US11518761, Example 159)copy SMILEScopy InChI
Affinity DataEC50:  460nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate measured after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C21CTPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50538670(CHEMBL4642579)copy SMILEScopy InChI
Affinity DataEC50:  5.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate measured after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C21CTPubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50538670(CHEMBL4642579)copy SMILEScopy InChI
Affinity DataEC50:  5.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate measured after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C21CTPubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50538670(CHEMBL4642579)copy SMILEScopy InChI
Affinity DataEC50:  5.00E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using S-mephenytoin as substrate measured after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C21CTPubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50538668(CHEMBL4634455 | US11518761, Example 159)copy SMILEScopy InChI
Affinity DataEC50:  5.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate measured after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C21CTPubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50538669(CHEMBL4646408)copy SMILEScopy InChI
Affinity DataEC50:  5.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate measured after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C21CTPubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50538668(CHEMBL4634455 | US11518761, Example 159)copy SMILEScopy InChI
Affinity DataEC50:  5.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate measured after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C21CTPubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50538669(CHEMBL4646408)copy SMILEScopy InChI
Affinity DataEC50:  5.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate measured after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C21CTPubMed
* indicates data uncertainty>20%