Compile Data Set for Download or QSAR

Found 22 hits of Enzyme Inhibition Constant Data   

TargetCasein kinase II subunit alpha 3(Homo sapiens)
Universidad San Pablo-CEU

Curated by ChEMBL
LigandPNGBDBM50539771(CHEMBL4649511)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human recombinant CK2 using RRRDDDSDDD peptide as substrate preincubated for 30 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3BCWPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Universidad San Pablo-CEU

Curated by ChEMBL
LigandPNGBDBM50539774(CHEMBL4648157)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3BCWPubMed
TargetCasein kinase II subunit alpha 3(Homo sapiens)
Universidad San Pablo-CEU

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human recombinant CK2 using RRRDDDSDDD peptide as substrate preincubated for 30 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Universidad San Pablo-CEU

Curated by ChEMBL
LigandPNGBDBM50539773(CHEMBL4637274)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3BCWPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Universidad San Pablo-CEU

Curated by ChEMBL
LigandPNGBDBM50539771(CHEMBL4649511)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human recombinant HDAC1 using fluorogenic substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3BCWPubMed
TargetCasein kinase II subunit alpha 3(Homo sapiens)
Universidad San Pablo-CEU

Curated by ChEMBL
LigandPNGBDBM50539769(CHEMBL4637423)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human recombinant CK2 using RRRDDDSDDD peptide as substrate preincubated for 30 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3BCWPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Universidad San Pablo-CEU

Curated by ChEMBL
LigandPNGBDBM50539773(CHEMBL4637274)copy SMILEScopy InChI
Affinity DataIC50: 4.40nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3BCWPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Universidad San Pablo-CEU

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)copy SMILEScopy InChI
Affinity DataIC50: 5.60nMAssay Description:Inhibition of human recombinant HDAC1 using fluorogenic substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3BCWPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Universidad San Pablo-CEU

Curated by ChEMBL
LigandPNGBDBM50539771(CHEMBL4649511)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant HDAC6 using fluorogenic substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3BCWPubMed
TargetCasein kinase II subunit alpha 3(Homo sapiens)
Universidad San Pablo-CEU

Curated by ChEMBL
LigandPNGBDBM50539770(CHEMBL4645915)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant CK2 using RRRDDDSDDD peptide as substrate preincubated for 30 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3BCWPubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Universidad San Pablo-CEU

Curated by ChEMBL
LigandPNGBDBM50539773(CHEMBL4637274)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of HER2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3BCWPubMed
TargetCasein kinase II subunit alpha 3(Homo sapiens)
Universidad San Pablo-CEU

Curated by ChEMBL
LigandPNGBDBM50539772(CHEMBL4637976)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant CK2 using RRRDDDSDDD peptide as substrate preincubated for 30 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3BCWPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Universidad San Pablo-CEU

Curated by ChEMBL
LigandPNGBDBM50539774(CHEMBL4648157)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3BCWPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Universidad San Pablo-CEU

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of human recombinant HDAC6 expressed in Escherichia coli BL21(DE3) cells using Boc-Lys(Ac)-AMC as substrate preincubated for 5 followed by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3BCWPubMedDrugBank
TargetHistone deacetylase 1(Homo sapiens (Human))
Universidad San Pablo-CEU

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of human recombinant HDAC1 expressed in Escherichia coli BL21(DE3) cells using KL177 as substrate preincubated for 5 followed by substrate...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Universidad San Pablo-CEU

Curated by ChEMBL
LigandPNGBDBM50539772(CHEMBL4637976)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of human recombinant HDAC1 using fluorogenic substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3BCWPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Universidad San Pablo-CEU

Curated by ChEMBL
LigandPNGBDBM50539770(CHEMBL4645915)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of human recombinant HDAC1 using fluorogenic substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3BCWPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Universidad San Pablo-CEU

Curated by ChEMBL
LigandPNGBDBM50539769(CHEMBL4637423)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Inhibition of human recombinant HDAC1 using fluorogenic substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3BCWPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Universidad San Pablo-CEU

Curated by ChEMBL
LigandPNGBDBM50470579(4sc-202 | Domatinostat)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Inhibition of KDM1A/LSD1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3BCWPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Universidad San Pablo-CEU

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 776nMAssay Description:Inhibition of human recombinant HDAC8 expressed in Escherichia coli BL21(DE3) cells using Boc-Lys(TFA)-AMC as substrate preincubated for 5 followed b...More data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Universidad San Pablo-CEU

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant HDAC4 expressed in Escherichia coli BL21(DE3) cells using Boc-Lys(TFA)-AMC as substrate preincubated for 5 followed b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3BCWPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Universidad San Pablo-CEU

Curated by ChEMBL
LigandPNGBDBM50470579(4sc-202 | Domatinostat)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3BCWPubMed
* indicates data uncertainty>20%