Compile Data Set for Download or QSAR

Found 24 hits of Enzyme Inhibition Constant Data   

TargetCoagulation factor XI(Homo sapiens (Human))
Bristol Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50541586(CHEMBL4638245)copy SMILEScopy InChI
Affinity DataKi:  0.260nMAssay Description:Inhibition of human factor11a using pyro-Glu-Pro-Arg-pNA(para-nitroaniline) substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50541581(CHEMBL4646341)copy SMILEScopy InChI
Affinity DataKi:  0.5nMAssay Description:Inhibition of human factor11a using pyro-Glu-Pro-Arg-pNA(para-nitroaniline) substrate by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MHGPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50541577(CHEMBL4646441)copy SMILEScopy InChI
Affinity DataKi:  0.600nMAssay Description:Inhibition of human factor11a using pyro-Glu-Pro-Arg-pNA(para-nitroaniline) substrate by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MHGPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50541576(CHEMBL4644510)copy SMILEScopy InChI
Affinity DataKi:  0.700nMAssay Description:Inhibition of human factor11a using pyro-Glu-Pro-Arg-pNA(para-nitroaniline) substrate by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MHGPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50541582(CHEMBL4636247)copy SMILEScopy InChI
Affinity DataKi:  0.900nMAssay Description:Inhibition of human factor11a using pyro-Glu-Pro-Arg-pNA(para-nitroaniline) substrate by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MHGPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50541579(CHEMBL4637480)copy SMILEScopy InChI
Affinity DataKi:  1.60nMAssay Description:Inhibition of human factor11a using pyro-Glu-Pro-Arg-pNA(para-nitroaniline) substrate by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MHGPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50541578(CHEMBL4638837)copy SMILEScopy InChI
Affinity DataKi:  1.80nMAssay Description:Inhibition of human factor11a using pyro-Glu-Pro-Arg-pNA(para-nitroaniline) substrate by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MHGPubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Bristol Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50541586(CHEMBL4638245)copy SMILEScopy InChI
Affinity DataKi:  1.90nMAssay Description:Inhibition of human activated protein C using pyro-Glu-Pro-Arg-pNA(para-nitroaniline) substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MHGPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50541580(CHEMBL4639313)copy SMILEScopy InChI
Affinity DataKi:  2.70nMAssay Description:Inhibition of human factor11a using pyro-Glu-Pro-Arg-pNA(para-nitroaniline) substrate by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MHGPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50541583(CHEMBL4633639)copy SMILEScopy InChI
Affinity DataKi:  4.5nMAssay Description:Inhibition of human factor11a using pyro-Glu-Pro-Arg-pNA(para-nitroaniline) substrate by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MHGPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50541585(CHEMBL4635155)copy SMILEScopy InChI
Affinity DataKi:  4.90nMAssay Description:Inhibition of human factor11a using pyro-Glu-Pro-Arg-pNA(para-nitroaniline) substrate by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MHGPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50541584(CHEMBL4639498)copy SMILEScopy InChI
Affinity DataKi:  14nMAssay Description:Inhibition of human factor11a using pyro-Glu-Pro-Arg-pNA(para-nitroaniline) substrate by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MHGPubMed
TargetChymotrypsinogen B2(Homo sapiens)
Bristol Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50541586(CHEMBL4638245)copy SMILEScopy InChI
Affinity DataKi:  20nMAssay Description:Inhibition of human chymotrypsin by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MHGPubMed
TargetCoagulation factor XII(Homo sapiens (Human))
Bristol Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50541586(CHEMBL4638245)copy SMILEScopy InChI
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of human factor-12a using H-(D)-CHT-Gly-ArgpNA substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MHGPubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Bristol Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50541586(CHEMBL4638245)copy SMILEScopy InChI
Affinity DataKi:  2.40E+3nMAssay Description:Inhibition of human factor-7a using H-(D)-Ile-Pro-Arg-pNA substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MHGPubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Bristol Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50541586(CHEMBL4638245)copy SMILEScopy InChI
Affinity DataKi:  4.10E+3nMAssay Description:Inhibition of human tissue-type plasminogen activator using methyl-sulfonyl-D-cyclohexylalanyl-Gly-Arg-pNA substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MHGPubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Bristol Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50541586(CHEMBL4638245)copy SMILEScopy InChI
Affinity DataKi: >6.00E+3nMAssay Description:Inhibition of human plasma kallikrein using H-(D)-Pro-Phe-Arg-pNA substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MHGPubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50541586(CHEMBL4638245)copy SMILEScopy InChI
Affinity DataKi: >9.00E+3nMAssay Description:Inhibition of human factor-10a using N-benzoyl-Ile-Glu-(OH,OMe)-Gly-Arg-pNA substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MHGPubMed
TargetProthrombin(Homo sapiens (Human))
Bristol Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50541586(CHEMBL4638245)copy SMILEScopy InChI
Affinity DataKi: >1.30E+4nMAssay Description:Inhibition of human thrombin using pyro-Glu-Pro-Arg-pNA(para-nitroaniline substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MHGPubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Bristol Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50541586(CHEMBL4638245)copy SMILEScopy InChI
Affinity DataKi: >1.50E+4nMAssay Description:Inhibition of human urokinase using pyro-Glu-Gly-Arg-pNA substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MHGPubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Bristol Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50541586(CHEMBL4638245)copy SMILEScopy InChI
Affinity DataKi: >1.50E+4nMAssay Description:Inhibition of human tissue-type plasminogen activator using H-(D)-Val-Leu-Lys-pNA substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MHGPubMed
TargetPlasminogen(Homo sapiens (Human))
Bristol Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50541586(CHEMBL4638245)copy SMILEScopy InChI
Affinity DataKi: >2.10E+4nMAssay Description:Inhibition of human plasmin using H-(D)-Val-Leu-Lys-pNA substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MHGPubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Bristol Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50541586(CHEMBL4638245)copy SMILEScopy InChI
Affinity DataKi: >2.70E+4nMAssay Description:Inhibition of human factor-9a using Methyl-sulfonyl-D-cyclohexylglycyl-Gly-Arg-AMC substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MHGPubMed
TargetKallikrein-1(Homo sapiens (Human))
Bristol Myers Squibb Company

Curated by ChEMBL
LigandPNGBDBM50541586(CHEMBL4638245)copy SMILEScopy InChI
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of human tissue kallikrein-1 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MHGPubMed
* indicates data uncertainty>20%