Compile Data Set for Download or QSAR

Found 46 hits of Enzyme Inhibition Constant Data   

LigandPNGBDBM50031491(2-propyl-4-(methythio)-1-[[[2'-[(propylamino)carbo...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Displacement of [125I]- Ang II from angiotensin II AT1 receptor in rat adrenal cortical microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37W78
LigandPNGBDBM50283002(3-(2'-Butyloxycarbonylsulfamoyl-3-chloro-biphenyl-...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Displacement of [125I]- Ang II from angiotensin II AT1 receptor in rat adrenal cortical microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37W78
LigandPNGBDBM50283000(4'-(4-Ethyl-5-formyl-2-propyl-imidazol-1-ylmethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Displacement of [125I]- Ang II from angiotensin II AT1 receptor in rat adrenal cortical microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37W78
LigandPNGBDBM50032364(4'-(5-Acetyl-4-ethyl-2-propyl-imidazol-1-ylmethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Displacement of [125I]- Ang II from angiotensin II AT1 receptor in rat adrenal cortical microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37W78
LigandPNGBDBM50032362(3-(2'-Isopentyloxycarbonylsulfamoyl-3-fluoro-biphe...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Displacement of [125I]- Ang II from angiotensin II AT1 receptor in rat adrenal cortical microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37W78
TargetType-2 angiotensin II receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50032362(3-(2'-Isopentyloxycarbonylsulfamoyl-3-fluoro-biphe...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Displacement of [125I]- Ang II from angiotensin II AT2 receptor in rat adrenal cortical microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37W78
LigandPNGBDBM50283001(4'-(4-Ethyl-5-formyl-2-propyl-imidazol-1-ylmethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Displacement of [125I]- Ang II from angiotensin II AT1 receptor in rat adrenal cortical microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37W78
LigandPNGBDBM50283006(3-(2'-Butyloxycarbonylsulfamoyl-biphenyl-4-ylmethy...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Displacement of [125I]- Ang II from angiotensin II AT1 receptor in rat adrenal cortical microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37W78
TargetType-2 angiotensin II receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50283000(4'-(4-Ethyl-5-formyl-2-propyl-imidazol-1-ylmethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Displacement of [125I]- Ang II from angiotensin II AT2 receptor in rat adrenal cortical microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37W78
LigandPNGBDBM50283008(4'-(5-Acetyl-4-ethyl-2-propyl-imidazol-1-ylmethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Displacement of [125I]- Ang II from angiotensin II AT1 receptor in rat adrenal cortical microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37W78
LigandPNGBDBM36645(CHEMBL291582 | L-707,581)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Displacement of [125I]- Ang II from angiotensin II AT1 receptor in rat adrenal cortical microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37W78
LigandPNGBDBM50283005(3-(2'-Butyloxycarbonylsulfamoyl-3-bromo-biphenyl-4...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Displacement of [125I]- Ang II from angiotensin II AT1 receptor in rat adrenal cortical microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37W78
LigandPNGBDBM50283003(4'-(5-Acetyl-4-ethyl-2-propyl-imidazol-1-ylmethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Displacement of [125I]- Ang II from angiotensin II AT1 receptor in rat adrenal cortical microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37W78
LigandPNGBDBM50049179(4'-(4-Ethyl-5-formyl-2-propyl-imidazol-1-ylmethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Displacement of [125I]- Ang II from angiotensin II AT1 receptor in rat adrenal cortical microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37W78
LigandPNGBDBM82428(CAS_124750-95-4 | CB91356279 | CHEMBL443269 | DuP ...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Displacement of [125I]- Ang II from angiotensin II AT1 receptor in rat adrenal cortical microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37W78
TargetType-2 angiotensin II receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50032364(4'-(5-Acetyl-4-ethyl-2-propyl-imidazol-1-ylmethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Displacement of [125I]- Ang II from angiotensin II AT2 receptor in rat adrenal cortical microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37W78
LigandPNGBDBM50032351(3-(2'-Butyloxycarbonylsulfamoyl-3-chloro-biphenyl-...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Displacement of [125I]- Ang II from angiotensin II AT1 receptor in rat adrenal cortical microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37W78
LigandPNGBDBM50049196(3-[3-Bromo-2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmeth...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Displacement of [125I]- Ang II from angiotensin II AT1 receptor in rat adrenal cortical microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37W78
LigandPNGBDBM50283009(4'-(4-Ethyl-5-formyl-2-propyl-imidazol-1-ylmethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Displacement of [125I]- Ang II from angiotensin II AT1 receptor in rat adrenal cortical microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37W78
LigandPNGBDBM50283007(3-(2'-Butyloxycarbonylsulfamoyl-3-methyl-biphenyl-...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Displacement of [125I]- Ang II from angiotensin II AT1 receptor in rat adrenal cortical microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37W78
TargetType-2 angiotensin II receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50283002(3-(2'-Butyloxycarbonylsulfamoyl-3-chloro-biphenyl-...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Displacement of [125I]- Ang II from angiotensin II AT2 receptor in rat adrenal cortical microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37W78
LigandPNGBDBM50282999(4'-(5-Acetyl-4-ethyl-2-propyl-imidazol-1-ylmethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Displacement of [125I]- Ang II from angiotensin II AT1 receptor in rat adrenal cortical microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37W78
LigandPNGBDBM50283012(3-(2'-Butyloxycarbonylsulfamoyl-3-nitro-biphenyl-4...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Displacement of [125I]- Ang II from angiotensin II AT1 receptor in rat adrenal cortical microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37W78
TargetType-2 angiotensin II receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50032351(3-(2'-Butyloxycarbonylsulfamoyl-3-chloro-biphenyl-...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Displacement of [125I]- Ang II from angiotensin II AT2 receptor in rat adrenal cortical microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37W78
LigandPNGBDBM50283004(5-Ethyl-3-[3-fluoro-2'-(1H-tetrazol-5-yl)-biphenyl...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Displacement of [125I]- Ang II from angiotensin II AT1 receptor in rat adrenal cortical microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37W78
TargetType-2 angiotensin II receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50283009(4'-(4-Ethyl-5-formyl-2-propyl-imidazol-1-ylmethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Displacement of [125I]- Ang II from angiotensin II AT2 receptor in rat adrenal cortical microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37W78
TargetType-2 angiotensin II receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50283001(4'-(4-Ethyl-5-formyl-2-propyl-imidazol-1-ylmethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Displacement of [125I]- Ang II from angiotensin II AT2 receptor in rat adrenal cortical microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37W78
LigandPNGBDBM50283013(3-[3-Chloro-2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmet...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Displacement of [125I]- Ang II from angiotensin II AT1 receptor in rat adrenal cortical microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37W78
TargetType-2 angiotensin II receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50283007(3-(2'-Butyloxycarbonylsulfamoyl-3-methyl-biphenyl-...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Displacement of [125I]- Ang II from angiotensin II AT2 receptor in rat adrenal cortical microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37W78
TargetType-2 angiotensin II receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50282999(4'-(5-Acetyl-4-ethyl-2-propyl-imidazol-1-ylmethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Displacement of [125I]- Ang II from angiotensin II AT2 receptor in rat adrenal cortical microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37W78
TargetType-2 angiotensin II receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50283005(3-(2'-Butyloxycarbonylsulfamoyl-3-bromo-biphenyl-4...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Displacement of [125I]- Ang II from angiotensin II AT2 receptor in rat adrenal cortical microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37W78
TargetType-2 angiotensin II receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50283012(3-(2'-Butyloxycarbonylsulfamoyl-3-nitro-biphenyl-4...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Displacement of [125I]- Ang II from angiotensin II AT2 receptor in rat adrenal cortical microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37W78
LigandPNGBDBM50283010(3-[3-Bromo-2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmeth...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Displacement of [125I]- Ang II from angiotensin II AT1 receptor in rat adrenal cortical microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37W78
TargetType-2 angiotensin II receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50283003(4'-(5-Acetyl-4-ethyl-2-propyl-imidazol-1-ylmethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Displacement of [125I]- Ang II from angiotensin II AT2 receptor in rat adrenal cortical microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37W78
LigandPNGBDBM50283011(5-Ethyl-3-[3-methyl-2'-(1H-tetrazol-5-yl)-biphenyl...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Displacement of [125I]- Ang II from angiotensin II AT1 receptor in rat adrenal cortical microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37W78
TargetType-2 angiotensin II receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50283006(3-(2'-Butyloxycarbonylsulfamoyl-biphenyl-4-ylmethy...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Displacement of [125I]- Ang II from angiotensin II AT2 receptor in rat adrenal cortical microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37W78
TargetType-2 angiotensin II receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50049196(3-[3-Bromo-2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmeth...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Compound was tested for the inhibition of angiotensin II AT2 receptor by displacement of [125I]- Ang II to rat adrenal cortical microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37W78
TargetType-2 angiotensin II receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50283008(4'-(5-Acetyl-4-ethyl-2-propyl-imidazol-1-ylmethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Displacement of [125I]- Ang II from angiotensin II AT2 receptor in rat adrenal cortical microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37W78
TargetType-2 angiotensin II receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50283013(3-[3-Chloro-2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmet...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Displacement of [125I]- Ang II from angiotensin II AT2 receptor in rat adrenal cortical microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37W78
TargetType-2 angiotensin II receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50049179(4'-(4-Ethyl-5-formyl-2-propyl-imidazol-1-ylmethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Displacement of [125I]- Ang II from angiotensin II AT2 receptor in rat adrenal cortical microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37W78
TargetType-2 angiotensin II receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50283010(3-[3-Bromo-2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmeth...)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Displacement of [125I]- Ang II from angiotensin II AT2 receptor in rat adrenal cortical microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37W78
TargetType-2 angiotensin II receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50031491(2-propyl-4-(methythio)-1-[[[2'-[(propylamino)carbo...)copy SMILEScopy InChI
Affinity DataIC50: 775nMAssay Description:Displacement of [125I]- Ang II from angiotensin II AT2 receptor in rat adrenal cortical microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37W78
TargetType-2 angiotensin II receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50283011(5-Ethyl-3-[3-methyl-2'-(1H-tetrazol-5-yl)-biphenyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]- Ang II from angiotensin II AT2 receptor in rat adrenal cortical microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37W78
TargetType-2 angiotensin II receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50283004(5-Ethyl-3-[3-fluoro-2'-(1H-tetrazol-5-yl)-biphenyl...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Displacement of [125I]- Ang II from angiotensin II AT2 receptor in rat adrenal cortical microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37W78
TargetType-2 angiotensin II receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM36645(CHEMBL291582 | L-707,581)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [125I]- Ang II from angiotensin II AT2 receptor in rat adrenal cortical microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37W78
TargetType-2 angiotensin II receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM82428(CAS_124750-95-4 | CB91356279 | CHEMBL443269 | DuP ...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [125I]- Ang II from angiotensin II AT2 receptor in rat adrenal cortical microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37W78
* indicates data uncertainty>20%