Compile Data Set for Download or QSAR

Found 17 hits of Enzyme Inhibition Constant Data   

TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286220(2-[(2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-2...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Displacement of [125I]- Substance P from human Neurokinin 1 (hNK1) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP463J
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50000041((+) (2-Methoxy-benzyl)-(2-phenyl-piperidin-3-yl)-a...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Displacement of [125I]- Substance P from human Neurokinin 1 (hNK1) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286216(2-[(2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-2...)copy SMILEScopy InChI
Affinity DataIC50: 0.630nMAssay Description:Displacement of [125I]- Substance P from human Neurokinin 1 (hNK1) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP463J
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50049468((2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-2-ph...)copy SMILEScopy InChI
Affinity DataIC50: 0.870nMAssay Description:Displacement of [125I]- Substance P from human Neurokinin 1 (hNK1) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP463J
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50052283(2-[(2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Displacement of [125I]- Substance P from human Neurokinin 1 (hNK1) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP463J
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286215(3-[(2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Displacement of [125I]- Substance P from human Neurokinin 1 (hNK1) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP463J
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286214(4-[(2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-2...)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Displacement of [125I]- Substance P from human Neurokinin 1 (hNK1) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP463J
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286218(CHEMBL67612 | [(2S,3S)-3-(3,5-Bis-trifluoromethyl-...)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Displacement of [125I]- Substance P from human Neurokinin 1 (hNK1) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP463J
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284632((2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-1-me...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Displacement of [125I]- Substance P from human Neurokinin 1 (hNK1) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP463J
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286217(2-[(2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-2...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Displacement of [125I]- Substance P from human Neurokinin 1 (hNK1) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP463J
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286223(1-[(2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-2...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Displacement of [125I]- Substance P from human Neurokinin 1 (hNK1) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP463J
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286213(CHEMBL302315 | [(2S,3S)-3-(3,5-Bis-trifluoromethyl...)copy SMILEScopy InChI
Affinity DataIC50: 68nMAssay Description:Displacement of [125I]- Substance P from human Neurokinin 1 (hNK1) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP463J
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286221(CHEMBL292496 | [(2S,3S)-3-(3,5-Bis-trifluoromethyl...)copy SMILEScopy InChI
Affinity DataIC50: 85nMAssay Description:Displacement of [125I]- Substance P from human Neurokinin 1 (hNK1) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP463J
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286219((2S,3S)-1-Benzyl-3-(3,5-bis-trifluoromethyl-benzyl...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Displacement of [125I]- Substance P from human Neurokinin 1 (hNK1) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP463J
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286222(2-[(2S,3S)-3-(2-Methoxy-benzylamino)-2-phenyl-pipe...)copy SMILEScopy InChI
Affinity DataIC50: 227nMAssay Description:Displacement of [125I]- Substance P from human Neurokinin 1 (hNK1) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP463J
TargetNeuromedin-K receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50049468((2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-2-ph...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Tested for inhibition of human Tachykinin receptor 3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP463J
TargetSubstance-K receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50049468((2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-2-ph...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Tested for inhibition of human Neurokinin Tachykinin receptor 2.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP463J
* indicates data uncertainty>20%