Compile Data Set for Download or QSAR

Found 36 hits of Enzyme Inhibition Constant Data   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287545(4-[4-Ethoxy-3-(1-methyl-7-oxo-3-propyl-6,7-dihydro...)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Inhibition of Phosphodiesterase 5 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DQW
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of Phosphodiesterase 5 from human corpus cavernosumMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of Phosphodiesterase 5 from human corpus cavernosumMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287543(5-(2-ethoxy-5-(piperazin-1-ylsulfonyl)phenyl)-1-me...)copy SMILEScopy InChI
Affinity DataIC50: 5.70nMAssay Description:Inhibition of Phosphodiesterase 5 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DQW
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287550(5-(2-ethoxy-5-(4-(2-hydroxyethyl)piperazin-1-ylsul...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of Phosphodiesterase 5 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DQW
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50111899(5-(2-Ethoxy-phenyl)-1-methyl-3-propyl-1,6-dihydro-...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of Phosphodiesterase 5 from human corpus cavernosumMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DQW
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50111899(5-(2-Ethoxy-phenyl)-1-methyl-3-propyl-1,6-dihydro-...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of Phosphodiesterase 5 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DQW
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50169640(5-(2-Ethoxy-phenyl)-3-propyl-1,6-dihydro-pyrazolo[...)copy SMILEScopy InChI
Affinity DataIC50: 82nMAssay Description:Inhibition of Phosphodiesterase 5 from human corpus cavernosumMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DQW
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50169640(5-(2-Ethoxy-phenyl)-3-propyl-1,6-dihydro-pyrazolo[...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of Phosphodiesterase 3 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DQW
LigandPNGBDBM50287545(4-[4-Ethoxy-3-(1-methyl-7-oxo-3-propyl-6,7-dihydro...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of Phosphodiesterase 1 from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DQW
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Inhibition of Phosphodiesterase 1 from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DQW
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287546(5-(2-Ethoxy-phenyl)-1,3-dimethyl-1,6-dihydro-pyraz...)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:Inhibition of Phosphodiesterase 5 from human corpus cavernosumMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DQW
LigandPNGBDBM50287543(5-(2-ethoxy-5-(piperazin-1-ylsulfonyl)phenyl)-1-me...)copy SMILEScopy InChI
Affinity DataIC50: 390nMAssay Description:Inhibition of Phosphodiesterase 1 from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DQW
LigandPNGBDBM50287550(5-(2-ethoxy-5-(4-(2-hydroxyethyl)piperazin-1-ylsul...)copy SMILEScopy InChI
Affinity DataIC50: 460nMAssay Description:Inhibition of Phosphodiesterase 1 from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DQW
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287551(CHEMBL52245 | N-(2-(1-methyl-7-oxo-3-propyl-6,7-di...)copy SMILEScopy InChI
Affinity DataIC50: 780nMAssay Description:Inhibition of Phosphodiesterase 5 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DQW
LigandPNGBDBM50111899(5-(2-Ethoxy-phenyl)-1-methyl-3-propyl-1,6-dihydro-...)copy SMILEScopy InChI
Affinity DataIC50: 790nMAssay Description:Inhibition of Phosphodiesterase 1 from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DQW
LigandPNGBDBM50169640(5-(2-Ethoxy-phenyl)-3-propyl-1,6-dihydro-pyrazolo[...)copy SMILEScopy InChI
Affinity DataIC50: 860nMAssay Description:Inhibition of Phosphodiesterase 1 from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DQW
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287549(5-(2-(cyclopropylmethoxy)phenyl)-1-methyl-3-propyl...)copy SMILEScopy InChI
Affinity DataIC50: 960nMAssay Description:Inhibition of Phosphodiesterase 5 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DQW
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287544(5-(2-Hydroxy-phenyl)-3-propyl-1,6-dihydro-pyrazolo...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Phosphodiesterase 5 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DQW
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM14363(3-(2-propoxyphenyl)-2,4,7,8,9-pentazabicyclo[4.3.0...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Phosphodiesterase 5 from human corpus cavernosumMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DQW
LigandPNGBDBM50287546(5-(2-Ethoxy-phenyl)-1,3-dimethyl-1,6-dihydro-pyraz...)copy SMILEScopy InChI
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of Phosphodiesterase 5 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DQW
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287547(1-Methyl-5-(2-nitro-phenyl)-3-propyl-1,6-dihydro-p...)copy SMILEScopy InChI
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of Phosphodiesterase 5 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DQW
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287548(5-Phenyl-3-propyl-1,6-dihydro-pyrazolo[4,3-d]pyrim...)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of Phosphodiesterase 5 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DQW
LigandPNGBDBM14363(3-(2-propoxyphenyl)-2,4,7,8,9-pentazabicyclo[4.3.0...)copy SMILEScopy InChI
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of Phosphodiesterase 1 from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DQW
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287545(4-[4-Ethoxy-3-(1-methyl-7-oxo-3-propyl-6,7-dihydro...)copy SMILEScopy InChI
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of Phosphodiesterase 3 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DQW
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287549(5-(2-(cyclopropylmethoxy)phenyl)-1-methyl-3-propyl...)copy SMILEScopy InChI
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition of Phosphodiesterase 3 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DQW
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287550(5-(2-ethoxy-5-(4-(2-hydroxyethyl)piperazin-1-ylsul...)copy SMILEScopy InChI
Affinity DataIC50: 6.20E+4nMAssay Description:Inhibition of Phosphodiesterase 5 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DQW
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287548(5-Phenyl-3-propyl-1,6-dihydro-pyrazolo[4,3-d]pyrim...)copy SMILEScopy InChI
Affinity DataIC50: 6.30E+4nMAssay Description:Inhibition of Phosphodiesterase 3 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DQW
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)copy SMILEScopy InChI
Affinity DataIC50: 6.50E+4nMAssay Description:Inhibition of Phosphodiesterase 3 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DQW
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287551(CHEMBL52245 | N-(2-(1-methyl-7-oxo-3-propyl-6,7-di...)copy SMILEScopy InChI
Affinity DataIC50: 8.30E+4nMAssay Description:Inhibition of Phosphodiesterase 3 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DQW
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287544(5-(2-Hydroxy-phenyl)-3-propyl-1,6-dihydro-pyrazolo...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Phosphodiesterase 3 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DQW
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50111899(5-(2-Ethoxy-phenyl)-1-methyl-3-propyl-1,6-dihydro-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Phosphodiesterase 3 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DQW
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM14363(3-(2-propoxyphenyl)-2,4,7,8,9-pentazabicyclo[4.3.0...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Phosphodiesterase 3 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DQW
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287543(5-(2-ethoxy-5-(piperazin-1-ylsulfonyl)phenyl)-1-me...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Phosphodiesterase 3 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DQW
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287546(5-(2-Ethoxy-phenyl)-1,3-dimethyl-1,6-dihydro-pyraz...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Phosphodiesterase 3 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DQW
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287547(1-Methyl-5-(2-nitro-phenyl)-3-propyl-1,6-dihydro-p...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Phosphodiesterase 3 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DQW
* indicates data uncertainty>20%