Compile Data Set for Download or QSAR

Found 10 hits of Enzyme Inhibition Constant Data   

TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292475(CHEMBL510130 | hypophyllanthin)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+4nMAssay Description:Displacement of [125I]endothelin-1 from human recombinant ETA receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7PV5
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292476(CHEMBL453822 | nirtetralin)copy SMILEScopy InChI
Affinity DataIC50: 7.50E+4nMAssay Description:Displacement of [125I]endothelin-1 from human recombinant ETA receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7PV5
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292478((2S,4S)-5,8-dimethoxy-6-methyl-4-phenyl-1,2,3,4-te...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+5nMAssay Description:Displacement of [125I]endothelin-1 from human recombinant ETA receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7PV5
TargetEndothelin-1 receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50292476(CHEMBL453822 | nirtetralin)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+5nMAssay Description:Displacement of [125I]endothelin-1 from ETA receptor in rat A10 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7PV5
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292475(CHEMBL510130 | hypophyllanthin)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+5nMAssay Description:Displacement of [125I]endothelin-1 from human recombinant ETB receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7PV5
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292477(CHEMBL453568 | phyllanthin)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+5nMAssay Description:Displacement of [125I]endothelin-1 from human recombinant ETB receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7PV5
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292476(CHEMBL453822 | nirtetralin)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+5nMAssay Description:Displacement of [125I]endothelin-1 from human recombinant ETB receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7PV5
TargetEndothelin-1 receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50292475(CHEMBL510130 | hypophyllanthin)copy SMILEScopy InChI
Affinity DataIC50: 5.80E+5nMAssay Description:Displacement of [125I]endothelin-1 from ETA receptor in rat A10 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7PV5
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292477(CHEMBL453568 | phyllanthin)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+6nMAssay Description:Displacement of [125I]endothelin-1 from human recombinant ETA receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7PV5
TargetEndothelin-1 receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50292477(CHEMBL453568 | phyllanthin)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+6nMAssay Description:Displacement of [125I]endothelin-1 from ETA receptor in rat A10 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7PV5
* indicates data uncertainty>20%