Compile Data Set for Download or QSAR

Found 8 hits of Enzyme Inhibition Constant Data   

TargetSubstance-K receptor(HAMSTER)
TBA

Curated by ChEMBL
LigandPNGBDBM50366377(CHEMBL334721 | MEN-10627)copy SMILEScopy InChI
Affinity DataIC50: 0.0790nMAssay Description:Tested for binding affinity of compound against [125I]NKA binding to neurokinin-2 (NK-2) receptor in hamster urinary bladderMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1ZDC
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50366377(CHEMBL334721 | MEN-10627)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Tested for binding affinity against [125I]BH-SP binding to neurokinin-1 (NK-1) receptor in human IM-9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1ZDC
TargetNeuromedin-K receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284763(1-(3-Benzyl-pyrrolidin-1-yl)-2-(1H-indol-3-yl)-eth...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+3nMAssay Description:Concentration producing half-maximal inhibition of specific binding of [3H]senktide to Tachykinin receptor 3 in the guinea pig cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1ZDC
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284763(1-(3-Benzyl-pyrrolidin-1-yl)-2-(1H-indol-3-yl)-eth...)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+3nMAssay Description:Tested for binding affinity against [125I]BH-SP binding to neurokinin-1 (NK-1) receptor in human IM-9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1ZDC
TargetSubstance-K receptor(HAMSTER)
TBA

Curated by ChEMBL
LigandPNGBDBM50289293(1N-[1-carbamoyl-2-phenyl-(1S)-ethyl]-2-amino-3-(1H...)copy SMILEScopy InChI
Affinity DataIC50: 5.20E+3nMAssay Description:Tested for binding affinity of compound against [125I]NKA binding to neurokinin-2 (NK-2) receptor in hamster urinary bladderMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1ZDC
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289294(3-Benzyl-2-aza-bicyclo[2.2.1]heptane-2-carboxylic ...)copy SMILEScopy InChI
Affinity DataIC50: 6.70E+3nMAssay Description:Tested for binding affinity against [125I]BH-SP binding to neurokinin-1 (NK-1) receptor in human IM-9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1ZDC
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289293(1N-[1-carbamoyl-2-phenyl-(1S)-ethyl]-2-amino-3-(1H...)copy SMILEScopy InChI
Affinity DataIC50: 9.30E+3nMAssay Description:Tested for binding affinity against [125I]BH-SP binding to neurokinin-1 (NK-1) receptor in human IM-9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1ZDC
TargetNeuromedin-K receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289295(3-{[(3-Benzyl-2-aza-bicyclo[2.2.1]heptane-2-carbon...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Tested for binding affinity of compound against [125I][MePhe]-NKB binding to Tachykinin receptor 3 in stably expressed CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1ZDC
* indicates data uncertainty>20%