Compile Data Set for Download or QSAR

Found 90 hits of Enzyme Inhibition Constant Data   

TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4078(6,7,13,14-tetrahydroxy-2,9-dioxatetracyclo[6.6.2.0...)copy SMILEScopy InChI
Affinity DataIC50: 300nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0648PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4117(3-phenyl-1-(1,2,6,7-tetrahydroxy-9H-carbazol-9-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0648PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4100(4-[(1,2,6,7-tetrahydroxy-9H-carbazol-9-yl)methyl]b...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0648PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4115(9-[(4-methanesulfonylphenyl)carbonyl]-9H-carbazole...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0648PubMed
LigandPNGBDBM4099(9-(3-phenylpropyl)-9H-carbazole-1,2,6,7-tetrol | C...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of PKA activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] label...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0648PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4109(9-(naphthalen-2-ylcarbonyl)-9H-carbazole-1,2,6,7-t...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0648PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4099(9-(3-phenylpropyl)-9H-carbazole-1,2,6,7-tetrol | C...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0648PubMed
LigandPNGBDBM4078(6,7,13,14-tetrahydroxy-2,9-dioxatetracyclo[6.6.2.0...)copy SMILEScopy InChI
Affinity DataIC50: 600nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of PKA activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] label...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0648PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4106(9-{[4-(benzenesulfonyl)phenyl]methyl}-9H-carbazole...)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0648PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4093(4-bromo-9H-carbazole-1,2,6,7-tetrol | Carbazole de...)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0648PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4108(9-[(4-phenylphenyl)carbonyl]-9H-carbazole-1,2,6,7-...)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0648PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4110(9-[(3-nitrophenyl)carbonyl]-9H-carbazole-1,2,6,7-t...)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0648PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4113(9-[(4-tert-butylphenyl)carbonyl]-9H-carbazole-1,2,...)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0648PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4111(9-{[4-(trifluoromethyl)phenyl]carbonyl}-9H-carbazo...)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0648PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4092(9H-carbazole-1,2,6,7-tetrol | Carbazole deriv. 9b)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0648PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4085(2,3,8,9-tetrahydroxy-5-[(4-nitrophenyl)methyl]-5,6...)copy SMILEScopy InChI
Affinity DataIC50: 900nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0648PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4080(2,3,7,8-tetrahydroxy-5,6-dihydrophenanthridin-6-on...)copy SMILEScopy InChI
Affinity DataIC50: 900nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0648PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4103(9-[(2,6-dichlorophenyl)methyl]-9H-carbazole-1,2,6,...)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0648PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4101(4-[(4-bromo-1,2,6,7-tetrahydroxy-9H-carbazol-9-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0648PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4097(9-benzoyl-9H-carbazole-1,2,6,7-tetrol | Carbazole ...)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0648PubMed
LigandPNGBDBM4109(9-(naphthalen-2-ylcarbonyl)-9H-carbazole-1,2,6,7-t...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of PKA activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] label...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0648PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4079(2,3,8,9-tetrahydroxy-5,6-dihydrophenanthridin-6-on...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0648PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4087(5-[(3,4-dichlorophenyl)methyl]-2,3,8,9-tetrahydrox...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0648PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4107(9-[(4-bromophenyl)carbonyl]-9H-carbazole-1,2,6,7-t...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0648PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4091(9H-carbazole-2,3,6,7-tetrol | Carbazole deriv. 9a)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0648PubMed
LigandPNGBDBM4110(9-[(3-nitrophenyl)carbonyl]-9H-carbazole-1,2,6,7-t...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of PKA activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] label...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0648PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4105(9-[(3-methylphenyl)methyl]-9H-carbazole-1,2,6,7-te...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0648PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4095(9-benzyl-9H-carbazole-1,2,6,7-tetrol | Carbazole d...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0648PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4112(4-bromo-9-{[4-(trifluoromethyl)phenyl]carbonyl}-9H...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0648PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4089(5-{[4-(benzenesulfonyl)phenyl]methyl}-2,3,8,9-tetr...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0648PubMed
LigandPNGBDBM4117(3-phenyl-1-(1,2,6,7-tetrahydroxy-9H-carbazol-9-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+3nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of PKA activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] label...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0648PubMed
LigandPNGBDBM4108(9-[(4-phenylphenyl)carbonyl]-9H-carbazole-1,2,6,7-...)copy SMILEScopy InChI
Affinity DataIC50: 3.20E+3nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of PKA activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] label...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0648PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4104(9-[(4-bromophenyl)methyl]-9H-carbazole-1,2,6,7-tet...)copy SMILEScopy InChI
Affinity DataIC50: 3.40E+3nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0648PubMed
LigandPNGBDBM4116(4-bromo-9-[(4-methanesulfonylphenyl)carbonyl]-9H-c...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of PKA activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] label...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0648PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4096(9-benzoyl-9H-carbazole-2,3,6,7-tetrol | Carbazole ...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0648PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4081(5-ethyl-2,3,8,9-tetrahydroxy-5,6-dihydrophenanthri...)copy SMILEScopy InChI
Affinity DataIC50: 4.10E+3nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0648PubMed
LigandPNGBDBM4107(9-[(4-bromophenyl)carbonyl]-9H-carbazole-1,2,6,7-t...)copy SMILEScopy InChI
Affinity DataIC50: 4.20E+3nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of PKA activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] label...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0648PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4083(5-(Phenylmethyl)-2,3,8,9-tetrahydroxy-6(5H)-phenan...)copy SMILEScopy InChI
Affinity DataIC50: 5.40E+3nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0648PubMed
LigandPNGBDBM4101(4-[(4-bromo-1,2,6,7-tetrahydroxy-9H-carbazol-9-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 6.60E+3nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of PKA activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] label...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0648PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4094(9-benzyl-9H-carbazole-2,3,6,7-tetrol | Carbazole d...)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+3nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0648PubMed
LigandPNGBDBM4112(4-bromo-9-{[4-(trifluoromethyl)phenyl]carbonyl}-9H...)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+3nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of PKA activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] label...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0648PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4090(5-{[4-(benzenesulfonyl)phenyl]methyl}-2,3,7,8-tetr...)copy SMILEScopy InChI
Affinity DataIC50: 7.20E+3nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0648PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4120(9-[(2,5-dichlorobenzene)sulfonyl]-9H-carbazole-1,2...)copy SMILEScopy InChI
Affinity DataIC50: 7.70E+3nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0648PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4098(9-(pyridin-3-ylmethyl)-9H-carbazole-2,3,6,7-tetrol...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0648PubMed
LigandPNGBDBM4085(2,3,8,9-tetrahydroxy-5-[(4-nitrophenyl)methyl]-5,6...)copy SMILEScopy InChI
Affinity DataIC50: 8.40E+3nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of PKA activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] label...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0648PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4102(9-{[4-(trifluoromethyl)phenyl]methyl}-9H-carbazole...)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+3nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0648PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4116(4-bromo-9-[(4-methanesulfonylphenyl)carbonyl]-9H-c...)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+3nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0648PubMed
LigandPNGBDBM4111(9-{[4-(trifluoromethyl)phenyl]carbonyl}-9H-carbazo...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of PKA activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] label...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0648PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4082(5-ethyl-2,3,7,8-tetrahydroxy-5,6-dihydrophenanthri...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+4nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0648PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

LigandPNGBDBM4122(9-[(4-nitrobenzene)sulfonyl]-9H-carbazole-1,2,6,7-...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0648PubMed
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