Compile Data Set for Download or QSAR

Found 32 hits of Enzyme Inhibition Constant Data   

TargetD(2) dopamine receptor(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)copy SMILEScopy InChI
Affinity DataKi:  0.5nMAssay Description:Tested for binding affinity towards human D2L receptor using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5M68PubMedDrugBank
TargetD(3) dopamine receptor(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)copy SMILEScopy InChI
Affinity DataKi:  0.690nMAssay Description:Tested for binding affinity towards human D3 receptor using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5M68PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)copy SMILEScopy InChI
Affinity DataKi:  1.86nMAssay Description:Tested for binding affinity towards rat striatal D2 receptor using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5M68PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50001955((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...)copy SMILEScopy InChI
Affinity DataKi:  2.20nMAssay Description:Tested for binding affinity towards rat striatal D2 receptor using [3H]-NPA as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5M68PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50048299(4-Phenyl-1-((R)-3-phenyl-cyclohex-3-enylmethyl)-1,...)copy SMILEScopy InChI
Affinity DataKi:  3.30nMAssay Description:Tested for binding affinity towards rat striatal D2 receptor using [3H]-NPA as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5M68PubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50001955((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...)copy SMILEScopy InChI
Affinity DataKi:  7.80nMAssay Description:Tested for binding affinity towards human D3 receptor using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5M68PubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50048299(4-Phenyl-1-((R)-3-phenyl-cyclohex-3-enylmethyl)-1,...)copy SMILEScopy InChI
Affinity DataKi:  17nMAssay Description:Tested for binding affinity towards human D3 receptor using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5M68PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50001955((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...)copy SMILEScopy InChI
Affinity DataKi:  17nMAssay Description:Tested for binding affinity towards rat striatal D2 receptor using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5M68PubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50048299(4-Phenyl-1-((R)-3-phenyl-cyclohex-3-enylmethyl)-1,...)copy SMILEScopy InChI
Affinity DataKi:  26nMAssay Description:Tested for binding affinity towards human D2L receptor using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5M68PubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50001955((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...)copy SMILEScopy InChI
Affinity DataKi:  28nMAssay Description:Tested for binding affinity towards human D2L receptor using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5M68PubMedDrugBank
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50048299(4-Phenyl-1-((R)-3-phenyl-cyclohex-3-enylmethyl)-1,...)copy SMILEScopy InChI
Affinity DataKi:  53nMAssay Description:Tested for binding affinity towards rat striatal D2 receptor using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5M68PubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50048299(4-Phenyl-1-((R)-3-phenyl-cyclohex-3-enylmethyl)-1,...)copy SMILEScopy InChI
Affinity DataKi:  91nMAssay Description:Tested for binding affinity towards human Dopamine receptor D4.2 using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5M68PubMed
TargetD(1A) dopamine receptor(RAT)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50001955((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...)copy SMILEScopy InChI
Affinity DataKi: >221nMAssay Description:Tested for binding affinity towards rat striatal dopamine receptor D1 using [3H]-SCH- 23390 as radioligandMore data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(RAT)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)copy SMILEScopy InChI
Affinity DataKi:  467nMAssay Description:Tested for binding affinity towards rat striatal dopamine receptor D1 using [3H]-SCH- 23390 as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5M68PubMed
TargetD(1A) dopamine receptor(RAT)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50048299(4-Phenyl-1-((R)-3-phenyl-cyclohex-3-enylmethyl)-1,...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Tested for binding affinity towards rat striatal dopamine receptor D1 using [3H]-SCH- 23390 as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5M68PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50048299(4-Phenyl-1-((R)-3-phenyl-cyclohex-3-enylmethyl)-1,...)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:In vitro inhibition of [3H]-spiperone binding to Dopamine D2 receptor in rat striatum.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5M68PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50037669(1-[(R)-3-(4-Fluoro-phenyl)-cyclohex-3-enylmethyl]-...)copy SMILEScopy InChI
Affinity DataIC50: 76nMAssay Description:In vitro inhibition of [3H]-spiperone binding to Dopamine D2 receptor in rat striatum.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5M68PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50037671(1-[(R)-3-(4-Methoxy-phenyl)-cyclohex-3-enylmethyl]...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:In vitro inhibition of [3H]-spiperone binding to Dopamine D2 receptor in rat striatum.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5M68PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50037670(4-Phenyl-1-(3-phenyl-cyclohex-3-enylmethyl)-1,2,3,...)copy SMILEScopy InChI
Affinity DataIC50: 112nMAssay Description:In vitro inhibition of [3H]-spiperone binding to Dopamine D2 receptor in rat striatum.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5M68PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50453436(CHEMBL2111778)copy SMILEScopy InChI
Affinity DataIC50: 113nMAssay Description:In vitro inhibition of [3H]-spiperone binding to Dopamine D2 receptor in rat striatum.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5M68PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50037674(1-(3-Phenyl-cyclohex-3-enylmethyl)-4-pyridin-2-yl-...)copy SMILEScopy InChI
Affinity DataIC50: 141nMAssay Description:In vitro inhibition of [3H]-spiperone binding to Dopamine D2 receptor in rat striatum.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5M68PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50037668(1-(3-Phenyl-cyclohex-3-enylmethyl)-4-thiophen-2-yl...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:In vitro inhibition of [3H]-spiperone binding to Dopamine D2 receptor in rat striatum.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5M68PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50037672(4-Phenyl-1-((R)-3-p-tolyl-cyclohex-3-enylmethyl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 328nMAssay Description:In vitro inhibition of [3H]-spiperone binding to Dopamine D2 receptor in rat striatum.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5M68PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50037667(2-[4-(3-Phenyl-cyclohex-3-enylmethyl)-piperazin-1-...)copy SMILEScopy InChI
Affinity DataIC50: 354nMAssay Description:In vitro inhibition of [3H]-spiperone binding to Dopamine D2 receptor in rat striatum.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5M68PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50037673(4-Phenyl-1-(3-phenyl-cyclohex-2-enylmethyl)-1,2,3,...)copy SMILEScopy InChI
Affinity DataIC50: 420nMAssay Description:In vitro inhibition of [3H]-spiperone binding to Dopamine D2 receptor in rat striatum.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5M68PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50037680(1-Phenyl-4-(3-phenyl-cyclohex-3-enylmethyl)-pipera...)copy SMILEScopy InChI
Affinity DataIC50: 424nMAssay Description:In vitro inhibition of [3H]-spiperone binding to Dopamine D2 receptor in rat striatum.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5M68PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50037679(4-Phenyl-1-[2-(3-phenyl-cyclohex-3-enyl)-ethyl]-1,...)copy SMILEScopy InChI
Affinity DataIC50: 635nMAssay Description:In vitro inhibition of [3H]-spiperone binding to Dopamine D2 receptor in rat striatum.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5M68PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50037681(4-Phenyl-1-(4-phenyl-cyclohex-3-enylmethyl)-1,2,3,...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibition of [3H]-spiperone binding to Dopamine D2 receptor in rat striatum.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5M68PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50037678(4-Phenyl-1-[(R)-3-(4-trifluoromethyl-phenyl)-cyclo...)copy SMILEScopy InChI
Affinity DataIC50: 2.55E+3nMAssay Description:In vitro inhibition of [3H]-spiperone binding to Dopamine D2 receptor in rat striatum.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5M68PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50037676(4-Phenyl-1-(2-phenyl-cyclohex-2-enylmethyl)-1,2,3,...)copy SMILEScopy InChI
Affinity DataIC50: 3.94E+3nMAssay Description:In vitro inhibition of [3H]-spiperone binding to Dopamine D2 receptor in rat striatum.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5M68PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50037675(1-[(R)-3-(4-Chloro-phenyl)-cyclohex-3-enylmethyl]-...)copy SMILEScopy InChI
Affinity DataIC50: 4.63E+3nMAssay Description:In vitro inhibition of [3H]-spiperone binding to Dopamine D2 receptor in rat striatum.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5M68PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50037677(4-Phenyl-1-(3-phenyl-cyclohex-3-enyl)-1,2,3,6-tetr...)copy SMILEScopy InChI
Affinity DataIC50: 9.21E+3nMAssay Description:In vitro inhibition of [3H]-spiperone binding to Dopamine D2 receptor in rat striatum.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5M68PubMed
* indicates data uncertainty>20%