Found 7 hits of Enzyme Inhibition Constant Data
TargetFolylpolyglutamate synthase, mitochondrial(Homo sapiens (Human))
University of Michigan
Curated by ChEMBL
University of Michigan
Curated by ChEMBL
Affinity DataKi: 200nMAssay Description:Inhibitory activity against mammalian Folyl-polyglutamate synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.820nMAssay Description:Inhibitory concentration against dihydrofolate reductase (DHFR) enzyme isolated from CCRF-CEM human leukemia cells.More data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
In DepthDetails
Article
BindingDB Entry DOI: 10.7270/Q2000158PubMedDrugBank
MMDB
PDB
3D Structure (crystal)
BindingDB Entry DOI: 10.7270/Q2000158PubMedDrugBank
MMDB
PDB
3D Structure (crystal)
Affinity DataIC50: 1nMAssay Description:Inhibitory concentration against dihydrofolate reductase enzyme (DHFR) enzyme isolated from CCRF-CEM human leukemia cells. value mentioned is from li...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibitory concentration against dihydrofolate reductase enzyme (DHFR) enzyme isolated from CCRF-CEM human leukemia cells.More data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibitory concentration against dihydrofolate reductase enzyme (DHFR) enzyme isolated from CCRF-CEM human leukemia cells.More data for this Ligand-Target Pair
TargetFolylpolyglutamate synthase, mitochondrial(Homo sapiens (Human))
University of Michigan
Curated by ChEMBL
University of Michigan
Curated by ChEMBL
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibitory concentration against human Folyl-polyglutamate synthase isolated from CCRF-CEM human leukemia cells.More data for this Ligand-Target Pair
TargetFolylpolyglutamate synthase, mitochondrial(Homo sapiens (Human))
University of Michigan
Curated by ChEMBL
University of Michigan
Curated by ChEMBL
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibitory concentration against human Folyl-polyglutamate synthase isolated from CCRF-CEM human leukemia cells.More data for this Ligand-Target Pair