Compile Data Set for Download or QSAR

Found 37 hits of Enzyme Inhibition Constant Data   

TargetEndothelin-1 receptor(Homo sapiens (Human))
ZENECA Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50422267(CHEMBL263079)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7HKTPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
ZENECA Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50422250(CHEMBL268174)copy SMILEScopy InChI
Affinity DataIC50: 7.90nMAssay Description:Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7HKTPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
ZENECA Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50422234(CHEMBL6412)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7HKTPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
ZENECA Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50422254(CHEMBL6785)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of specific binding of [125-I] ET-1 to human Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7HKTPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
ZENECA Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50422257(CHEMBL6555)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7HKTPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
ZENECA Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50034435(5-Dimethylamino-naphthalene-1-sulfonic acid (3,4-d...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7HKTPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
ZENECA Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50422248(CHEMBL6800)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7HKTPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
ZENECA Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50422244(CHEMBL268339)copy SMILEScopy InChI
Affinity DataIC50: 126nMAssay Description:Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7HKTPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
ZENECA Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50422246(CHEMBL6553)copy SMILEScopy InChI
Affinity DataIC50: 158nMAssay Description:Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7HKTPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
ZENECA Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50422264(CHEMBL6761)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7HKTPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
ZENECA Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50422243(CHEMBL6297)copy SMILEScopy InChI
Affinity DataIC50: 251nMAssay Description:Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7HKTPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
ZENECA Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50422249(CHEMBL266277)copy SMILEScopy InChI
Affinity DataIC50: 251nMAssay Description:Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7HKTPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
ZENECA Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50422265(CHEMBL268116)copy SMILEScopy InChI
Affinity DataIC50: 316nMAssay Description:Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7HKTPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
ZENECA Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50422233(CHEMBL6624)copy SMILEScopy InChI
Affinity DataIC50: 316nMAssay Description:Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7HKTPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
ZENECA Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50422241(CHEMBL415106)copy SMILEScopy InChI
Affinity DataIC50: 398nMAssay Description:Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7HKTPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
ZENECA Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50422245(CHEMBL6588)copy SMILEScopy InChI
Affinity DataIC50: 501nMAssay Description:Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7HKTPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
ZENECA Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50422266(CHEMBL7019)copy SMILEScopy InChI
Affinity DataIC50: 631nMAssay Description:Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7HKTPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
ZENECA Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50422263(CHEMBL6382)copy SMILEScopy InChI
Affinity DataIC50: 631nMAssay Description:Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7HKTPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
ZENECA Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50422258(CHEMBL6399)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7HKTPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
ZENECA Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50422261(CHEMBL415292)copy SMILEScopy InChI
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7HKTPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
ZENECA Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50422253(CHEMBL6583)copy SMILEScopy InChI
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7HKTPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
ZENECA Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50422262(CHEMBL6433)copy SMILEScopy InChI
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7HKTPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
ZENECA Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50422240(CHEMBL6411)copy SMILEScopy InChI
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7HKTPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
ZENECA Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50422256(CHEMBL268387)copy SMILEScopy InChI
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7HKTPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
ZENECA Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50422236(CHEMBL6463)copy SMILEScopy InChI
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7HKTPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
ZENECA Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50422255(CHEMBL6630)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7HKTPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
ZENECA Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50422237(CHEMBL266315)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7HKTPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
ZENECA Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50422238(CHEMBL6576)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7HKTPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
ZENECA Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50422247(CHEMBL6543)copy SMILEScopy InChI
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7HKTPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
ZENECA Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50422242(CHEMBL6400)copy SMILEScopy InChI
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7HKTPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
ZENECA Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50422232(CHEMBL269237)copy SMILEScopy InChI
Affinity DataIC50: 3.98E+3nMAssay Description:Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7HKTPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
ZENECA Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50422251(CHEMBL6660)copy SMILEScopy InChI
Affinity DataIC50: 5.01E+3nMAssay Description:Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7HKTPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
ZENECA Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50422259(CHEMBL266684)copy SMILEScopy InChI
Affinity DataIC50: 5.01E+3nMAssay Description:Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7HKTPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
ZENECA Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50422235(CHEMBL6647)copy SMILEScopy InChI
Affinity DataIC50: 5.01E+3nMAssay Description:Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7HKTPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
ZENECA Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50422239(CHEMBL6468)copy SMILEScopy InChI
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7HKTPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
ZENECA Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50422252(CHEMBL6778)copy SMILEScopy InChI
Affinity DataIC50: 7.94E+3nMAssay Description:Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7HKTPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
ZENECA Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50422260(CHEMBL6566)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7HKTPubMed
* indicates data uncertainty>20%